Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Zeinab Dalloul"'
Autor:
Nicolas Denis-Lagache, Christelle Oblet, Tiffany Marchiol, Audrey Baylet, Ophélie Têteau, Iman Dalloul, Zeinab Dalloul, Lina Zawil, Ophélie Dézé, Jeanne Cook-Moreau, Alexis Saintamand, Hend Boutouil, Ahmed Amine Khamlichi, Claire Carrion, Sophie Péron, Sandrine Le Noir, Brice Laffleur, Michel Cogné
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn mature B cells, activation-induced deaminase reshapes Ig genes through somatic hypermutation and class switch recombination of the Ig heavy chain (IgH) locus under control of its 3’ cis-regulatory region (3’RR). The 3’RR is itsel
Externí odkaz:
https://doaj.org/article/138b735a8308469d92f827d4c9644e6a
UnAIDed Class Switching in Activated B-Cells Reveals Intrinsic Features of a Self-Cleaving IgH Locus
Autor:
Iman Dalloul, Brice Laffleur, Zeinab Dalloul, Batoul Wehbi, Florence Jouan, Baptiste Brauge, Paco Derouault, Jeanne Moreau, Sven Kracker, Alain Fischer, Anne Durandy, Sandrine Le Noir, Michel Cogné
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Activation-induced deaminase (AID) is the major actor of immunoglobulin (Ig) gene diversification in germinal center B-cells. From its first description, it was considered as mandatory for class switch recombination (CSR), and this discovery initiate
Externí odkaz:
https://doaj.org/article/1d9f8414d03043ce9311e61b783fb76a
Autor:
Zeinab Dalloul, Marie Best, Pauline Chenuet, Iman Dalloul, Sandrine Le Noir, Dieudonnée Togbé, Mylène Gador, Bernhard Ryffel, Valerie FJ Quesniaux, Yolla El Makhour, François Boyer, Jean‐Claude Aldigier, Jeanne Cook‐Moreau, Nicolas Fazilleau, Michel Cogné
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 6, Pp n/a-n/a (2021)
Abstract Objectives Inhibitors of bromodomain and extra terminal domain (BET) proteins are a new and growing class of anti‐cancer drugs, which decrease oncogene expression by targeting superenhancers. Antibody production is another physiological pr
Externí odkaz:
https://doaj.org/article/7f4552b0dd5f47e48599bdbc8b3cbc6d
Autor:
Iman Dalloul, François Boyer, Zeinab Dalloul, Amandine Pignarre, Gersende Caron, Thierry Fest, Fabrice Chatonnet, Céline Delaloy, Anne Durandy, Robin Jeannet, Emilie Lereclus, Hend Boutouil, Jean-Claude Aldigier, Sophie Péron, Sandrine Le Noir, Jeanne Cook-Moreau, Michel Cogné
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1007721 (2019)
B-cell activation yields abundant cell death in parallel to clonal amplification and remodeling of immunoglobulin (Ig) genes by activation-induced deaminase (AID). AID promotes affinity maturation of Ig variable regions and class switch recombination
Externí odkaz:
https://doaj.org/article/b008f55c724e43988bbb8e81994f41ac
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Memory B cells and long-lived plasma cells are key elements of adaptive humoral immunity. Regardless of the immunoglobulin class produced, these cells can ensure long-lasting protection but also long-lasting immunopathology, thus requiring tight regu
Externí odkaz:
https://doaj.org/article/0595a923dc3d43cd844e2a0c1b2ba164
Publikováno v:
Gene. 861:147232
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29e0dcbf5f3e94c10d1b36611d2efae3
https://doi.org/10.1016/j.gene.2023.147232
https://doi.org/10.1016/j.gene.2023.147232
Autor:
Firas Kobeissy, Khalil Mallah, Kazem Zibara, Fatima Dakroub, Zeinab Dalloul, Mohammad Nasser, Leila Nasrallah, Zahraa Mallah, Ghewa A. El-Achkar, Naify Ramadan, Wael Mohamed, Stefania Mondello, Hala Darwish, Eva Hamade, Aida Habib
Publikováno v:
Neurochemistry international. 154
Traumatic Brain Injury (TBI) is one of the leading causes of death and disability worldwide. Aspirin (ASA) and clopidogrel (CLOP) are antiplatelet agents that inhibit platelet aggregation. They are implicated in worsening the intracerebral haemorrhag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f913c122836aca697700839a65c10e6e
https://pubmed.ncbi.nlm.nih.gov/35121011
https://pubmed.ncbi.nlm.nih.gov/35121011
Autor:
Bernhard Ryffel, Yolla Makhour, Zeinab Dalloul, Pauline Chenuet, Jean-Claude Aldigier, Michel Cogné, François Boyer, Marie Best, Valérie F. J. Quesniaux, Sandrine Le Noir, Dieudonnée Togbe, Jeanne Cook-Moreau, Mylène Gador, Nicolas Fazilleau, Iman Dalloul
Publikováno v:
Clinical and Translational Immunology
Clinical and Translational Immunology, 2021, 10 (6), pp.e1280. ⟨10.1002/cti2.1280⟩
Clinical and Translational Immunology, Nature Publishing Group, 2021, 10 (6), pp.e1280. ⟨10.1002/cti2.1280⟩
Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 10, Iss 6, Pp n/a-n/a (2021)
Clinical and Translational Immunology, 2021, 10 (6), pp.e1280. ⟨10.1002/cti2.1280⟩
Clinical and Translational Immunology, Nature Publishing Group, 2021, 10 (6), pp.e1280. ⟨10.1002/cti2.1280⟩
Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 10, Iss 6, Pp n/a-n/a (2021)
Objectives Inhibitors of bromodomain and extra terminal domain (BET) proteins are a new and growing class of anti‐cancer drugs, which decrease oncogene expression by targeting superenhancers. Antibody production is another physiological process rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fee329423492909008c682edd2c8e2e
https://doi.org/10.1002/cti2.1280
https://doi.org/10.1002/cti2.1280
Publikováno v:
The Journal of Immunology. 208:109.17-109.17
The number of people living with a chronic inflammatory lung disease, such as asthma, is constantly increasing. The development of resistance to existing therapies and the fact that exposure to air pollution and particular matter are continuously inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11018a81d51689c8af847f9b14ef55e4
https://doi.org/10.4049/jimmunol.208.supp.109.17
https://doi.org/10.4049/jimmunol.208.supp.109.17
Autor:
Erwan Scaon, Sophie Péron, Jeanne Cook-Moreau, Iman Dalloul, Michel Cogné, Jean-Claude Aldigier, Zeinab Dalloul, Bastien Hervé, François Boyer, Claire Carrion, Hend Boutouil
Publikováno v:
The Journal of Immunology. 198:4148-4155
B cells ensure humoral immune responses due to the production of Ag-specific memory B cells and Ab-secreting plasma cells. In secondary lymphoid organs, Ag-driven B cell activation induces terminal maturation and Ig isotype class switch (class switch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d75e06556c2c0f583e6ea5fc75e815
https://doi.org/10.4049/jimmunol.1601924
https://doi.org/10.4049/jimmunol.1601924