Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Zeinab Asgarian"'
Autor:
Matt S. Dawson, Kevin Gordon-Fleet, Lingxin Yan, Vera Tardos, Huanying He, Kwong Mui, Smriti Nawani, Zeinab Asgarian, Marco Catani, Cathy Fernandes, Uwe Drescher
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract A biological understanding of the apparent sex bias in autism is lacking. Here we have identified Cntnap2 KO mice as a model system to help better understand this dimorphism. Using this model, we observed social deficits in juvenile male KO
Externí odkaz:
https://doaj.org/article/ca32b9a7cffa47a9a578226203e68896
Autor:
Lorenza Magno, Zeinab Asgarian, Migle Apanaviciute, Yasmin Milner, Nora Bengoa-Vergniory, Anna Noren Rubin, Nicoletta Kessaris
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Cre transgene-based fate mapping in mice reveals that most septal neurons originate from progenitor domains in the septum and identifies Bsx as an embryonic marker and essential regulator of glutamatergic neuron development and locomotion behaviour.
Externí odkaz:
https://doaj.org/article/46ce62f914df4e1290d81a4df49037b2
Autor:
Zeinab Asgarian, Marcio Guiomar Oliveira, Agata Stryjewska, Ioannis Maragkos, Anna Noren Rubin, Lorenza Magno, Vassilis Pachnis, Mohammadmersad Ghorbani, Scott Wayne Hiebert, Myrto Denaxa, Nicoletta Kessaris
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
There is a large diversity of inhibitory interneurons in the mammalian cerebral cortex. How this emerges during embryogenesis remains unclear. Here, the authors identify MTG8 as a co-factor of LHX6 and a new regulator of cortical interneuron developm
Externí odkaz:
https://doaj.org/article/00979fa66fb446ab972a14461acf5a6a
Publikováno v:
Stem Cell Reports, Vol 13, Iss 5, Pp 793-802 (2019)
Summary: Oriens lacunosum-moleculare (O-LM) interneurons constitute 40% of hippocampal interneurons expressing Somatostatin (SST). Recent evidence has indicated a dual origin for these cells in the medial and caudal ganglionic eminences (MGE and CGE)
Externí odkaz:
https://doaj.org/article/169d175e91ea479dac6f2012566036a9
Autor:
Lorenza Magno, Zeinab Asgarian, Valentina Pendolino, Theodora Velona, Albert Mackintosh, Flora Lee, Agata Stryjewska, Celine Zimmer, François Guillemot, Mark Farrant, Beverley Clark, Nicoletta Kessaris
Publikováno v:
Cell Reports, Vol 35, Iss 11, Pp 109249- (2021)
Summary: Cortical GABAergic interneurons are generated in large numbers in the ganglionic eminences and migrate into the cerebral cortex during embryogenesis. At early postnatal stages, during neuronal circuit maturation, autonomous and activity-depe
Externí odkaz:
https://doaj.org/article/e2d0408bf0594de0a7200913d8bf8c4f
Autor:
John R. Counsell, Zeinab Asgarian, Jinhong Meng, Veronica Ferrer, Conrad A. Vink, Steven J. Howe, Simon N. Waddington, Adrian J. Thrasher, Francesco Muntoni, Jennifer E. Morgan, Olivier Danos
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Duchenne Muscular Dystrophy (DMD) is caused by a lack of dystrophin expression in patient muscle fibres. Current DMD gene therapy strategies rely on the expression of internally deleted forms of dystrophin, missing important functional domai
Externí odkaz:
https://doaj.org/article/a4e4bc5af0674a76abc106a806bbacbb
Autor:
François Guillemot, Beverley A. Clark, Lorenza Magno, Zeinab Asgarian, Mark Farrant, Theodora Velona, Albert Mackintosh, Flora Lee, Agata Stryjewska, Valentina Pendolino, Nicoletta Kessaris, Celine Zimmer
Publikováno v:
Cell Reports
Cell Reports, Vol 35, Iss 11, Pp 109249-(2021)
Cell Reports, Vol 35, Iss 11, Pp 109249-(2021)
Summary Cortical GABAergic interneurons are generated in large numbers in the ganglionic eminences and migrate into the cerebral cortex during embryogenesis. At early postnatal stages, during neuronal circuit maturation, autonomous and activity-depen
Autor:
Francesco Muntoni, Jinhong Meng, Simon N. Waddington, Adrian J. Thrasher, Olivier Danos, Conrad A. Vink, Veronica Ferrer, Jennifer E. Morgan, Steven J. Howe, John R. Counsell, Zeinab Asgarian
Publikováno v:
Scientific Reports. 7
Scientific Reports 7: Article number: 44775; published online: 17 March 2017; updated: 29 August 2017. This article was published twice in error during a change in production systems. The publisher apologizes to the authors and readers for the error.
Autor:
Olivier Danos, Simon N. Waddington, Zeinab Asgarian, Veronica Ferrer, Jinhong Meng, Francesco Muntoni, Adrian J. Thrasher, Steven J. Howe, Conrad A. Vink, John R. Counsell, Jennifer E. Morgan
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Duchenne Muscular Dystrophy (DMD) is caused by a lack of dystrophin expression in patient muscle fibres. Current DMD gene therapy strategies rely on the expression of internally deleted forms of dystrophin, missing important functional domains. Viral
Autor:
Jinhong Meng, Francesco Muntoni, Olivier Danos, Veronica Ferrer, Steven J. Howe, Jennifer E. Morgan, Zeinab Asgarian, John R. Counsell
Publikováno v:
Molecular Therapy. 23:S211-S212
Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin expression in patient muscle cells. Restoration of dystrophin expression could alleviate the symptoms of DMD, although the large size of full-length dystrophin cDNA (11.1kb) and the re