Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Zehong Miao"'
Autor:
Yiyue Ge, Tingzhong Tian, Suling Huang, Fangping Wan, Jingxin Li, Shuya Li, Xiaoting Wang, Hui Yang, Lixiang Hong, Nian Wu, Enming Yuan, Yunan Luo, Lili Cheng, Chengliang Hu, Yipin Lei, Hantao Shu, Xiaolong Feng, Ziyuan Jiang, Yunfu Wu, Ying Chi, Xiling Guo, Lunbiao Cui, Liang Xiao, Zeng Li, Chunhao Yang, Zehong Miao, Ligong Chen, Haitao Li, Hainian Zeng, Dan Zhao, Fengcai Zhu, Xiaokun Shen, Jianyang Zeng
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-16 (2021)
Abstract The global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requires an urgent need to find effective therapeutics for the treatment of coronavirus disease 2019 (COVID-19). In this study, we developed an integrative dru
Externí odkaz:
https://doaj.org/article/4f3f4d21df9d4b8b88ef95b4b0a08a89
Publikováno v:
Molecules, Vol 24, Iss 16, p 3017 (2019)
Herein, a direct strategy to synthesize 3-(2-hydroxybenzoyl)-1-aza-anthraquinones with excellent efficiency, mild conditions, and benign functional group compatibility was reported. A variety of 3-formylchromone compounds were employed as compatible
Externí odkaz:
https://doaj.org/article/5706de60694d47b7b22802418cde535c
Autor:
Menglan Luo, Qian Wu, Yueyue Yang, Lin Sun, Xiajuan Huan, Changqing Tian, Bing Xiong, Zehong Miao, Yingqing Wang, Danqi Chen
Publikováno v:
European journal of medicinal chemistry. 239
Bromodomain and extraterminal domain (BET) subfamily members are intriguing targets for cancer treatment. Most of the reported BET inhibitors were monovalent inhibitors. Recently, some bivalent inhibitors were disclosed, which bound to two bromodomai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e3680d69260e753706ce5a53718273
https://pubmed.ncbi.nlm.nih.gov/35714446
https://pubmed.ncbi.nlm.nih.gov/35714446
Autor:
Ligong Chen, Liang Xiao, Chunhao Yang, Ziyuan Jiang, Haidong Tang, Huang S, Xiaokun Shen, Dan Zhao, Lixiang Hong, Fengcai Zhu, Lili Cheng, Hantao Shu, Xiaolong Feng, Xiling Guo, Zeng Li, Lunbiao Cui, Yipin Lei, Fangping Wan, Hui Yang, Jianyang Zeng, Zehong Miao, Enming Yuan, Ying Chi, Tingzhong Tian, J Li, Shuya Li, Yiyue Ge, Hainian Zeng, Nian Wu
The global spread of SARS-CoV-2 requires an urgent need to find effective therapeutics for the treatment of COVID-19. We developed a data-driven drug repositioning framework, which applies both machine learning and statistical analysis approaches to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2cab450467144bcd7a4cb6305eaa81
Publikováno v:
Journal of Clinical Oncology. 37:e13539-e13539
e13539 Background: Glioma is the most common, deadly, and difficult-to-treat intracranial tumor. Up to 70% of gliomas are found to carry isocitrate dehydrogenase (IDH) mutations, which induce a homologous recombination defect (HRD) that renders gliom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50ada8f082e50fa2b31dc7f0d5d43bb3
https://doi.org/10.1200/jco.2019.37.15_suppl.e13539
https://doi.org/10.1200/jco.2019.37.15_suppl.e13539
Autor:
Xiaopin Duan, Haijun Yu, Yaping Li, Qi Yin, Jisheng Xiao, Chunying Chen, Zhiwen Zhang, Zehong Miao, Jun Wang
Publikováno v:
Biomaterials. 34:5381-5390
Metastasis is one of the greatest challenges in cancer treatment. In this study, a bioreducible polymer, Tween 85-s-s-polyethyleneimine 2K (TSP), was synthesized and used as a non-viral gene vector for p65 shRNA to block NF-κB signaling pathway, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae3dc5b02972debf7fda4e0d5c84e972
https://doi.org/10.1016/j.biomaterials.2013.03.084
https://doi.org/10.1016/j.biomaterials.2013.03.084
Publikováno v:
Carbohydrate Research. 334:159-164
Nine glycosides bearing the disaccharide of OSW-1, namely 2-O-(4-methoxybenzoyl)-beta-D-xylopyranosyl-(1-->3)-2-O-acetyl-alpha-L-arabinopyranosides, were synthesized, and their antitumor activities were tested.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef57da2ffeceba2189088e9c60d1f87
https://doi.org/10.1016/s0008-6215(01)00171-9
https://doi.org/10.1016/s0008-6215(01)00171-9
Autor:
Chunyong Ding, Qianting Tian, Jie Li, Mingkun Jiao, Shanshan Song, Yingqing Wang, Zehong Miao, Ao Zhang
Publikováno v:
Journal of Medicinal Chemistry; 2/8/2018, Vol. 61 Issue 3, p760-776, 17p
Publikováno v:
ChemInform. 32
Nine glycosides bearing the disaccharide of OSW-1, namely 2-O-(4-methoxybenzoyl)-beta-D-xylopyranosyl-(1-->3)-2-O-acetyl-alpha-L-arabinopyranosides, were synthesized, and their antitumor activities were tested.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31dc2b2b4bbf2e6de8a7ae2aa4d38f6f
https://doi.org/10.1002/chin.200149159
https://doi.org/10.1002/chin.200149159
Autor:
Zehong Miao, Jian Ding, Qin Liu, Zijian Guo, Xiao-Zeng You, Junyong Zhang, Ying Shao, Chun-Ying Duan
Publikováno v:
Journal of the Chemical Society, Dalton Transactions. :591
The design of Pt(II) complexes with novel structural features is of great relevance in the search for new anticancer agents with innovative chemical and biological properties. In this work we have synthesised and structurally characterised three nove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::386d374ca7b91c3fc6a39adc4adc8736
https://doi.org/10.1039/b108378n
https://doi.org/10.1039/b108378n