Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Zef Konst"'
Autor:
Daniel W. Robbins, Nivetha Brathaban, Dane E. Karr, Austin Tenn-McClellan, Arthur T. Sands, Jun Ma, May Tan, Gwenn M. Hansen, Timothy Ingallinera, Jenny McKinnell, Cristiana Guiducci, Ryan Rountree, Aileen Kelly, Zef Konst, Luz Perez, Mark Noviski
Publikováno v:
Blood. 138:2251-2251
Bruton's tyrosine kinase (BTK) plays a key role in cell survival in B cell malignancies, and covalent inhibitors of BTK, such as ibrutinib and acalabrutinib, have proven efficacious in chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f9e8e6d28add21cfafc5080ef439b17
https://doi.org/10.1182/blood-2021-147473
https://doi.org/10.1182/blood-2021-147473
Autor:
Liping Fang, Takao Suzuki, Kristian Jensen, Mats A. Svensson, Robert Pelleltier, Jeffrey A. Bell, Zef Konst, Hamish Wright, Wayne Tang, Katherine Amberg-Johnson, Shuping Xu, Xianhai Huang, Karen Dingley, Yan Zhang, Heng Qian, Markus K. Dahlgren, Michael Trzoss, Alan Futran, Karen Akinsanya, Xiaoxiao Yang, Sarah Boyce, Saidi He, Li Xing, Jiayi Xu, Tao Guo, David Madge, Tao Lu, Heidi Koldsoe, Fang-Yu Lin, Zhaowu Xu, Jie Xu, Engin Yapici
Publikováno v:
Cancer Research. 81:1338-1338
Introduction: Ubiquitin-specific protease 7 (USP7) is a deubiquitinase that regulates several proteins involved in cell cycle, DNA repair, genomic stability, and epigenetics and has been implicated in cancer progression. A key substrate of USP7 is MD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4c1ff969e5c86bbe7c27e29c7581d36
https://doi.org/10.1158/1538-7445.am2021-1338
https://doi.org/10.1158/1538-7445.am2021-1338
Autor:
Ryan Rountree, Dane E Karr, Luz Perez, Austin Tenn-McClellan, G. Hansen, Jenny McKinnell, Zef Konst, Mark Noviski, M. Tan, Aileen Kelly, Timothy Ingallinera, Daniel W. Robbins, Cristiana Guiducci
Publikováno v:
Annals of the Rheumatic Diseases. 80:204.1-205
Background:Aberrant activation of B cells and autoantibody mediated tissue damage are hallmarks of autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Therefore, novel treatments that prevent autoantibody gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8105690a77d5a499911df154f261b6c2
https://doi.org/10.1136/annrheumdis-2021-eular.1675
https://doi.org/10.1136/annrheumdis-2021-eular.1675
Autor:
Jennifer Tung, Luz Perez, Timothy Ingallinera, Jordan Ye, Aileen Kelly, May Tan, Ge Peng, Sasha Borodovsky, Zef Konst, Austin Tenn-McClellan, Ryan Rountree, Steve Basham, Jeffrey H. Wu, Jenny McKinnell, Dahlia Weiss, Arthur T. Sands, Cristiana Guiducci, Mark Noviski, Mcintosh Joel, Dane E Karr, Janine Powers, Daniel W. Robbins, Daisuke Kato, Anna Kolobova, Jeffrey T. Mihalic
Publikováno v:
Blood. 136:34-34
Bruton's tyrosine kinase (BTK) plays a key role in cell survival in B cell malignancies, such as chronic lymphocytic leukemia (CLL). Covalent inhibitors of BTK, such as ibrutinib and acalabrutinib, while effective, have been associated with the occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::492f0dbdb2ad9ad3c62ea1d2da14dc82
https://doi.org/10.1182/blood-2020-141461
https://doi.org/10.1182/blood-2020-141461
Autor:
Christoph W. Zapf, May Tan, Mario G. Cardozo, Ge Peng, Jennifer Tung, Mcintosh Joel, Arthur T. Sands, Ryan Rountree, Zef Konst, Jordan Ye, Aileen Kelly, Jeffrey H. Wu, Luz Perez, Neil Bence, Timothy Ingallinera, Dahlia Weiss, Mark Noviski, Steve Basham, Austin Tenn-McClellan, Jenny McKinnell, Daisuke Kato, Anna Kolobova, Jeffrey T. Mihalic, Daniel W. Robbins, Dane E Karr
Publikováno v:
Blood. 134:3805-3805
Bruton's tyrosine kinase (BTK) is a key component of B cell receptor signaling and is involved in B cell development and function. BTK plays a crucial role in cell survival in B cell malignancies such as Chronic Lymphocytic Leukemia (CLL), and covale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b95ae450ec2bc4afe8f06a32c74d624
https://doi.org/10.1182/blood-2019-129262
https://doi.org/10.1182/blood-2019-129262