Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Zeev Dvashi"'
Publikováno v:
Journal of Ophthalmology, Vol 2017 (2017)
Purpose. This study aimed to investigate the effect of OM-101 on the fibrotic response occurring in proliferative vitreoretinopathy (PVR) in an animal model. Methods. Antifibrotic effect of OM-101 was investigated in vivo. As control, eight weeks old
Externí odkaz:
https://doaj.org/article/9ae6b6fd48da4db99359cf7df736bf12
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122229 (2015)
BACKGROUND AND AIM:Proliferative vitreoretinopathy (PVR) is an active process that develops as a complication upon retinal detachment (RD), accompanied by formation of fibrotic tissue. The main cells involved in the development of fibrotic tissue dur
Externí odkaz:
https://doaj.org/article/bca4fcc8c5f54c959450abe77d82a2fd
Publikováno v:
Biochemistry and Cell Biology. 94:188-196
Autophagy is an evolutionarily conserved mechanism for degrading long-lived or malfunctioning proteins and organelles, such as those resulting from oxidative stress. Several publications have demonstrated the importance of the autophagy process in th
Autor:
Mordechai Rosner, Sara Lavi, Meytal Shohat, Ronit Satchi-Fainaro, Arieh S. Solomon, Hadas Sar Shalom, Daniella Ben-Meir, Ruth Ashery-Padan, Zeev Dvashi, Shiran Ferber
Publikováno v:
The American Journal of Pathology. 184:2936-2950
Protein phosphatase magnesium dependent 1A (PPM1A) has been implicated in fibrosis and skin wounding. We generated PPM1A knockout mice to study the role of PPM1A in the wound healing–inflammation–angiogenesis cross talk. The role of PPM1A in thes
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122229 (2015)
PLoS ONE
PLoS ONE
Background and Aim Proliferative vitreoretinopathy (PVR) is an active process that develops as a complication upon retinal detachment (RD), accompanied by formation of fibrotic tissue. The main cells involved in the development of fibrotic tissue dur
Publikováno v:
Investigative ophthalmologyvisual science. 55(9)
Purpose Oxidative stress and cellular senescence are known to contribute to the development of AMD; however, the mechanism is not fully understood. This study investigated the role of TGF-β-activated kinase 1 (TAK1) in the senescence of RPE cells as
Publikováno v:
Cellular & Molecular Biology Letters
Oocyte maturation in mammals is a multiple-stage process that generates fertilizable oocytes. Ovarian oocytes are arrested at prophase of the first meiotic division characterized by the presence of a germinal vesicle. Towards ovulation, the oocytes r