Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Zeenat Asghar"'
Autor:
Jessica L. Saben, Anna L. Boudoures, Zeenat Asghar, Alysha Thompson, Andrea Drury, Wendy Zhang, Maggie Chi, Andrew Cusumano, Suzanne Scheaffer, Kelle H. Moley
Publikováno v:
Cell Reports, Vol 16, Iss 1, Pp 1-8 (2016)
Maternal obesity impairs offspring health, but the responsible mechanisms are not fully established. To address this question, we fed female mice a high-fat/high-sugar diet from before conception until weaning and then followed the outcomes in the ne
Externí odkaz:
https://doaj.org/article/fd3e0cd963c94c2d8858a94f397594ec
Autor:
Zeenat Asghar, Andrea M. Drury, Kelle H. Moley, Suzanne M. Scheaffer, Maggie M.-Y. Chi, Anna L. Boudoures, Andrew Cusumano, Jessica Saben, Alysha Thompson, Wendy Zhang
Publikováno v:
Cell Reports, Vol 16, Iss 1, Pp 1-8 (2016)
SummaryMaternal obesity impairs offspring health, but the responsible mechanisms are not fully established. To address this question, we fed female mice a high-fat/high-sugar diet from before conception until weaning and then followed the outcomes in
Autor:
Claire S Stephens, Zeenat Asghar, Maggie M.-Y. Chi, Jessica Saben, Allyson L. Mayer, J.S. Rhee, Kelle H. Moley, M. Schulte
Publikováno v:
Human Reproduction. 31:1315-1326
STUDY QUESTION What effect does diet-induced obesity have on endometrial stromal cell (ESC) decidualization? SUMMARY ANSWER Diet-induced obesity impairs ESC decidualization. WHAT IS KNOWN ALREADY Decidualization is important for successful implantati
Autor:
Kelle H. Moley, Zeenat Asghar, Jessica Saben, Suzanne M. Scheaffer, J.S. Rhee, Andrea M. Drury
Publikováno v:
Endocrinology. 157:956-968
The most significant increase in metabolic syndrome over the previous decade occurred in women of reproductive age, which is alarming given that metabolic syndrome is associated with reproductive problems including subfertility and early pregnancy lo
Increased sugar consumption, particularly fructose, in the form of sweetened beverages and sweeteners in our diet adversely affects metabolic health. Because these effects are associated with features of the metabolic syndrome in humans, the direct e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64769648280bbfd1722916e203449c80
https://europepmc.org/articles/PMC5336566/
https://europepmc.org/articles/PMC5336566/
Autor:
Suzanne M. Scheaffer, Kelle H. Moley, Zeenat Asghar, Noor Al-Hammadi, Alysha Thompson, Maggie M.-Y. Chi, Jessica Saben, Andrew Cusumano
Publikováno v:
Scientific Reports
Maternal metabolic diseases increase offspring risk for low birth weight and cardiometabolic diseases in adulthood. Excess fructose consumption may confer metabolic risks for both women and their offspring. However, the direct consequences of fructos
Autor:
Shoshana Yakar, Stephanie Pack, William Jou, Oksana Gavrilova, Zeenat Asghar, Yuka Toyoshima, Derek LeRoith, Michael B. Wheeler
Publikováno v:
Endocrinology. 146:4024-4035
Leptin has metabolic effects on peripheral tissues including muscle, liver, and pancreas, and it has been successfully used to treat lipodystrophic diabetes, a leptin-deficient state. To study whether leptin therapy can be used for treatment of more
Autor:
Martin Haluzik, Daphne Yau, Marc L. Reitman, Bethel Stannard, Michael B. Wheeler, Homeostasis Kim, Shoshana Yakar, Lisa Heron-Milhavet, Jamie W. Joseph, Zeenat Asghar, Derek LeRoith, Ana M. Fernandez
Publikováno v:
Scopus-Elsevier
Abnormalities in insulin action are the characteristics of type 2 diabetes. Dominant-negative muscle-specific IGF-I receptor (MKR) mice exhibit elevated lipid levels at an early age and eventually develop type 2 diabetes. To evaluate the role of elev
Publikováno v:
Reproduction Abstracts.
Autor:
William Jou, Shoshana Yakar, Michael B. Wheeler, Desmond Hunt, Jamie W. Joseph, Martin Haluzik, Lisa Heron-Milhavet, Daphne Yau, Hyunsook Kim, Stephanie Pack, Nada A. Abumrad, Zeenat Asghar, Azeddine Ibrahimi, Oksana Gavrilova, Derek LeRoith
Publikováno v:
Endocrinology. 145(10)
Insulin resistance is one of the primary characteristics of type 2 diabetes. Mice overexpressing a dominant-negative IGF-I receptor specifically in muscle (MKR mice) demonstrate severe insulin resistance with high levels of serum and tissue lipids an