Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Zedan Zhang"'
Autor:
Zedan Zhang, Yi Wang, Wuping Yang, Tao Liu, Chuandong Wang, Cong Huang, Yawei Xu, Xiaolin Chen, Jingcheng Zhou, Yizhou Wang, Xiaohua Zhou, Yanqing Gong, Kan Gong
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110357- (2024)
Summary: Von Hippel-Lindau (VHL) syndrome is a rare autosomal dominant disorder, where renal cell carcinoma (RCC) serves as a significant cause of mortality. We collected peripheral blood from 61 VHL-RCC patients and 31 healthy individuals, along wit
Externí odkaz:
https://doaj.org/article/c1c4c0d76a5c4ac3be500027dd9ddf13
Autor:
Yawei Xu, Lei Li, Wuping Yang, Kenan Zhang, Zedan Zhang, Chaojian Yu, Jianhui Qiu, Lin Cai, Yanqing Gong, Zheng Zhang, Jingcheng Zhou, Kan Gong
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)
Abstract Background The management of advanced clear cell renal cell carcinoma (ccRCC) remains a major challenge in clinical practice, and the construction of more reliable prognostic prediction models and the further elucidation of key molecular mec
Externí odkaz:
https://doaj.org/article/5e9aa579138d449faad4502a2269c6cb
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Objective Real-world data (RWD) and real-world evidence (RWE) have been paid more and more attention in recent years. We aimed to evaluate the reporting quality of cohort studies using real-world data (RWD) published between 2013 and 2021 an
Externí odkaz:
https://doaj.org/article/e44b9c97c0504973b0575431dd806e27
Autor:
Hongkai Zhuang, Zedan Zhang, Bo Chen, Chenwei Tang, Xinming Chen, Wenliang Tan, Lei Yang, Zhiqin Xie, Xiaowu Ma, Qingbin Wang, Bingkun Wang, Changzhen Shang, Yajin Chen
Publikováno v:
Journal of Big Data, Vol 10, Iss 1, Pp 1-18 (2023)
Abstract Hepatocellular carcinoma (HCC) has a desmoplastic and hypoxic tumor microenvironment (TME), resulting in poor prognosis and treatment resistance. This study aimed to construct a novel prognostic classifier to investigate the degree of hypoxi
Externí odkaz:
https://doaj.org/article/1c360d248b6544aca0016575ef4643bf
Autor:
Wuping Yang, Zedan Zhang, Lei Li, Kenan Zhang, Yawei Xu, Mancheng Xia, Jingcheng Zhou, Yanqing Gong, Jinchao Chen, Kan Gong
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-12 (2023)
Abstract Recent evidences have suggested that Zinc finger protein 582 (ZNF582) plays different important roles in various tumors, but its clinical role, biological function and regulatory mechanism in clear cell renal cell carcinoma (ccRCC) are still
Externí odkaz:
https://doaj.org/article/759be62d030f4caf89bd48484843067a
Autor:
Zhi-Can Li, Min Huang, Qing-Yang Yao, Cai-Hong Lin, Bing-Cong Hong, Jie-Hua Wang, Zedan Zhang
Publikováno v:
Journal of Integrative Neuroscience, Vol 23, Iss 1, p 3 (2024)
Background: The impact of the methylenetetrahydrofolate reductase (MTHFR) C677T mutation on the relationship between plasma homocysteine (Hcy) levels and stroke has been extensively studied and documented in previous study. However, it remains unclea
Externí odkaz:
https://doaj.org/article/dc3587d132d74b5eaca99c9c8f804dee
Autor:
Tianyi Zhao, Zedan Zhang, Yitao Li, Zhihua Sun, Liangbo Liu, Xingmei Deng, Jia Guo, Dexin Zhu, Shuzhu Cao, Yingjin Chai, Usevich Vera Nikolaevna, Suleimenov Maratbek, Zhen Wang, Hui Zhang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectivesThe mechanism of Brucella infection regulating macrophage phenotype has not been completely elucidated until now. This study aimed to determine the mechanism of Brucella abortus in the modulation of macrophage phenotype using RAW264.7 cells
Externí odkaz:
https://doaj.org/article/4a1a39fdc94e4adbae7192f395aa975b
Autor:
Hongkai Zhuang, Shanzhou Huang, Zixuan Zhou, Zuyi Ma, Zedan Zhang, Chuanzhao Zhang, Baohua Hou
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Pancreatic cancer (PC) is one of the most common cancers and the leading cause of cancer-related death worldwide. Exploring novel predictive biomarkers for PC patients’ prognosis is in urgent need. Methods In the present study,
Externí odkaz:
https://doaj.org/article/1d7108fd6a9a4a0fa6e0f2c141751505
Autor:
Zedan Zhang, Yanlin Tang, Lei Li, Wuping Yang, Yawei Xu, Jingcheng Zhou, Kaifang Ma, Kenan Zhang, Hongkai Zhuang, Yanqing Gong, Kan Gong
Publikováno v:
Journal of Immunology Research, Vol 2022 (2022)
Background. FXYD2, a gene coding for the γ subunit of Na+/K+-ATPase, was demonstrated to involve in carcinogenesis recently. However, the specific role of FXYD2 in clear cell renal cell carcinoma (ccRCC) remains unknown. The current study was conduc
Externí odkaz:
https://doaj.org/article/0b47f4c934f847dc87c6e8d842ecf064
Autor:
Hongkai Zhuang, Shujie Wang, Bo Chen, Zedan Zhang, Zuyi Ma, Zhenchong Li, Chunsheng Liu, Zixuan Zhou, Yuanfeng Gong, Shanzhou Huang, Baohua Hou, Yajin Chen, Chuanzhao Zhang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Pancreatic ductal adenocarcinoma (PDAC) has a hypoxic and desmoplastic tumor microenvironment (TME), leading to treatment failure. We aimed to develop a prognostic classifier to evaluate hypoxia status and hypoxia-related molecular characteristics of
Externí odkaz:
https://doaj.org/article/f01bb09807914c998608fb4ce4f0fc3a