Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Zebrafish/metabolism"'
Autor:
Gabriela Arias‐Alpizar, Panagiota Papadopoulou, Xabier Rios, Krishna Reddy Pulagam, Mohammad‐Amin Moradi, Roy Pattipeiluhu, Jeroen Bussmann, Nico Sommerdijk, Jordi Llop, Alexander Kros, Frederick Campbell
Publikováno v:
Advanced Healthcare Materials, 12(10):2202709. WILEY
Advanced Healthcare Materials, 12, 10
Advanced Healthcare Materials, 12(10):2202709. Wiley
Advanced Healthcare Materials, 12, 10
Advanced Healthcare Materials, 12(10):2202709. Wiley
Plasma lipid transport and metabolism is essential to ensure correct cellular function throughout the body. Dynamically regulated in time and space, the well characterized mechanisms underpinning plasma lipid transport and metabolism offer an enticin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ca2e2633662d767ca25a0f9a40017a
https://doi.org/10.1002/adhm.202202709
https://doi.org/10.1002/adhm.202202709
Autor:
Willekers, Sven, Tessadori, Federico, van der Vaart, Babet, Henning, Heiko H., Stucchi, Riccardo, Altelaar, Maarten, Roelen, Bernard A.J., Akhmanova, Anna, Bakkers, Jeroen, Sub Cell Biology, Voortplanting paard, Afd Biomol.Mass Spect. and Proteomics, Anatomie en fysiologie, Celbiologie, Al het onderzoek van de faculteit Diergeneeskunde, CS_Cancer
Publikováno v:
Development (Cambridge, England), 149(16), 1. Company of Biologists Ltd
Development (Cambridge), 149(16). Company of Biologists Ltd
Development (Cambridge), 149(16). Company of Biologists Ltd
In embryos of most animal species, the zygotic centrosome is assembled by the centriole derived from the sperm cell and pericentriolar proteins present in the oocyte. This zygotic centrosome acts as a microtubule organizing center (MTOC) to assemble
Autor:
Zayana M. Al-Dahmani, Xiaogang Li, Lucas M. Wiggenhauser, Hannes Ott, Paul D. Kruithof, Sergey Lunev, Fernando A. Batista, Yang Luo, Amalia M. Dolga, Nicholas M. Morton, Matthew R. Groves, Jens Kroll, Harry van Goor
Publikováno v:
Scientific Reports, 12(1):12077. Nature Publishing Group
Thiosulfate sulfurtransferase (TST, EC 2.8.1.1), also known as Rhodanese, was initially discovered as a cyanide detoxification enzyme. However, it was recently also found to be a genetic predictor of resistance to obesity-related type 2 diabetes. Dia
Autor:
Anja Holm, Marie-Laure Possovre, Mojtaba Bandarabadi, Kristine F. Moseholm, Jessica L. Justinussen, Ivan Bozic, René Lemcke, Yoan Arribat, Francesca Amati, Asli Silahtaroglu, Maxime Juventin, Antoine Adamantidis, Mehdi Tafti, Birgitte R. Kornum
Publikováno v:
Holm, Anja; Possovre, Marie-Laure; Bandarabadi, Mojtaba; Moseholm, Kristine F; Justinussen, Jessica L; Bozic, Ivan; Lemcke, René; Arribat, Yoan; Amati, Francesca; Silahtaroglu, Asli; Juventin, Maxime; Adamantidis, Antoine; Tafti, Mehdi; Kornum, Birgitte R (2022). The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio. Proceedings of the National Academy of Sciences of the United States of America-PNAS, 119(17), e2112225119. National Academy of Sciences NAS 10.1073/pnas.2112225119
Holm, A, Possovre, M-L, Bandarabadi, M, Moseholm, K F, Justinussen, J L, Bozic, I, Lemcke, R, Arribat, Y, Amati, F, Silahtaroglu, A, Juventin, M, Adamantidis, A, Tafti, M & Kornum, B R 2022, ' The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 17, e2112225119, pp. e2112225119 . https://doi.org/10.1073/pnas.2112225119
Holm, A, Possovre, M L, Bandarabadi, M, Moseholm, K F, Justinussen, J L, Bozic, I, Lemcke, R, Arribat, Y, Amati, F, Silahtaroglu, A, Juventin, M, Adamantidis, A, Tafti, M & Kornum, B R 2022, ' The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 17 . https://doi.org/10.1073/pnas.2112225119
Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 17, pp. e2112225119
Holm, A, Possovre, M-L, Bandarabadi, M, Moseholm, K F, Justinussen, J L, Bozic, I, Lemcke, R, Arribat, Y, Amati, F, Silahtaroglu, A, Juventin, M, Adamantidis, A, Tafti, M & Kornum, B R 2022, ' The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 17, e2112225119, pp. e2112225119 . https://doi.org/10.1073/pnas.2112225119
Holm, A, Possovre, M L, Bandarabadi, M, Moseholm, K F, Justinussen, J L, Bozic, I, Lemcke, R, Arribat, Y, Amati, F, Silahtaroglu, A, Juventin, M, Adamantidis, A, Tafti, M & Kornum, B R 2022, ' The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio ', Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 17 . https://doi.org/10.1073/pnas.2112225119
Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 17, pp. e2112225119
Hypocretin (Hcrt), also known as orexin, neuropeptide signaling stabilizes sleep and wakefulness in all vertebrates. A lack of Hcrt causes the sleep disorder narcolepsy, and increased Hcrt signaling has been speculated to cause insomnia, but while th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5daa4e77ffd8aa8cbc665cd9fc957acc
https://boris.unibe.ch/169463/1/pnas.2112225119.pdf
https://boris.unibe.ch/169463/1/pnas.2112225119.pdf
Autor:
Kin Ki Jim, Rieza Aprianto, Rutger Koning, Arnau Domenech, Jun Kurushima, Diederik van de Beek, Christina M.J.E. Vandenbroucke-Grauls, Wilbert Bitter, Jan-Willem Veening
Publikováno v:
Cell Reports, 41(12):111851, 1-22. Cell Press
Jim, K K, Aprianto, R, Koning, R, Domenech, A, Kurushima, J, van de Beek, D, Vandenbroucke-Grauls, C M J E, Bitter, W & Veening, J-W 2022, ' Pneumolysin promotes host cell necroptosis and bacterial competence during pneumococcal meningitis as shown by whole-animal dual RNA-seq ', Cell Reports, vol. 41, no. 12, 111851 . https://doi.org/10.1016/j.celrep.2022.111851
Cell reports, vol. 41, no. 12, pp. 111851
Cell reports, 41(12):111851. Cell Press
Jim, K K, Aprianto, R, Koning, R, Domenech, A, Kurushima, J, van de Beek, D, Vandenbroucke-Grauls, C M J E, Bitter, W & Veening, J W 2022, ' Pneumolysin promotes host cell necroptosis and bacterial competence during pneumococcal meningitis as shown by whole-animal dual RNA-seq ', Cell Reports, vol. 41, no. 12, 111851, pp. 1-22 . https://doi.org/10.1016/j.celrep.2022.111851
Cell Reports, 41(12):111851. Cell Press
Jim, K K, Aprianto, R, Koning, R, Domenech, A, Kurushima, J, van de Beek, D, Vandenbroucke-Grauls, C M J E, Bitter, W & Veening, J-W 2022, ' Pneumolysin promotes host cell necroptosis and bacterial competence during pneumococcal meningitis as shown by whole-animal dual RNA-seq ', Cell Reports, vol. 41, no. 12, 111851 . https://doi.org/10.1016/j.celrep.2022.111851
Cell reports, vol. 41, no. 12, pp. 111851
Cell reports, 41(12):111851. Cell Press
Jim, K K, Aprianto, R, Koning, R, Domenech, A, Kurushima, J, van de Beek, D, Vandenbroucke-Grauls, C M J E, Bitter, W & Veening, J W 2022, ' Pneumolysin promotes host cell necroptosis and bacterial competence during pneumococcal meningitis as shown by whole-animal dual RNA-seq ', Cell Reports, vol. 41, no. 12, 111851, pp. 1-22 . https://doi.org/10.1016/j.celrep.2022.111851
Cell Reports, 41(12):111851. Cell Press
Pneumolysin is a major virulence factor of Streptococcus pneumoniae that plays a key role in interaction with the host during invasive disease. How pneumolysin influences these dynamics between host and pathogen interaction during early phase of cent
Autor:
Naomi Issler, Sara Afonso, Irith Weissman, Katrin Jordan, Alberto Cebrian-Serrano, Katrin Meindl, Eileen Dahlke, Konstantin Tziridis, Guanhua Yan, José M. Robles-López, Lydia Tabernero, Vaksha Patel, Anne Kesselheim, Enriko D. Klootwijk, Horia C. Stanescu, Simona Dumitriu, Daniela Iancu, Mehmet Tekman, Monika Mozere, Graciana Jaureguiberry, Priya Outtandy, Claire Russell, Anna-Lena Forst, Christina Sterner, Elena-Sofia Heinl, Helga Othmen, Ines Tegtmeier, Markus Reichold, Ina Maria Schiessl, Katharina Limm, Peter Oefner, Ralph Witzgall, Lifei Fu, Franziska Theilig, Achim Schilling, Efrat Shuster Biton, Limor Kalfon, Ayalla Fedida, Elite Arnon-Sheleg, Ofer Ben Izhak, Daniella Magen, Yair Anikster, Holger Schulze, Christine Ziegler, Martin Lowe, Benjamin Davies, Detlef Böckenhauer, Robert Kleta, Tzipora C. Falik Zaccai, Richard Warth
Publikováno v:
J Am Soc Nephrol
Issler, N, Afonso, S, Weissman, I, Jordan, K, Cebrian-Serrano, A, Meindl, K, Dahlke, E, Tziridis, K, Yan, G, Robles-López, J M, Tabernero, L, Patel, V, Kesselheim, A, Klootwijk, E D, Stanescu, H C, Dumitriu, S, Iancu, D, Tekman, M, Mozere, M, Jaureguiberry, G, Outtandy, P, Russell, C, Forst, A-L, Sterner, C, Heinl, E-S, Othmen, H, Tegtmeier, I, Reichold, M, Schiessl, I M, Limm, K, Oefner, P, Witzgall, R, Fu, L, Theilig, F, Schilling, A, Shuster Biton, E, Kalfon, L, Fedida, A, Arnon-Sheleg, E, Ben Izhak, O, Magen, D, Anikster, Y, Schulze, H, Ziegler, C, Lowe, M, Davies, B, Böckenhauer, D, Kleta, R, Falik Zaccai, T C & Warth, R 2022, ' A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness ', Journal of the American Society of Nephrology : JASN, vol. 33, no. 4, pp. 732-745 . https://doi.org/10.1681/ASN.2021101312
Issler, N, Afonso, S, Weissman, I, Jordan, K, Cebrian-Serrano, A, Meindl, K, Dahlke, E, Tziridis, K, Yan, G, Robles-López, J M, Tabernero, L, Patel, V, Kesselheim, A, Klootwijk, E D, Stanescu, H C, Dumitriu, S, Iancu, D, Tekman, M, Mozere, M, Jaureguiberry, G, Outtandy, P, Russell, C, Forst, A-L, Sterner, C, Heinl, E-S, Othmen, H, Tegtmeier, I, Reichold, M, Schiessl, I M, Limm, K, Oefner, P, Witzgall, R, Fu, L, Theilig, F, Schilling, A, Shuster Biton, E, Kalfon, L, Fedida, A, Arnon-Sheleg, E, Ben Izhak, O, Magen, D, Anikster, Y, Schulze, H, Ziegler, C, Lowe, M, Davies, B, Böckenhauer, D, Kleta, R, Falik Zaccai, T C & Warth, R 2022, ' A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness ', Journal of the American Society of Nephrology : JASN, vol. 33, no. 4, pp. 732-745 . https://doi.org/10.1681/ASN.2021101312
BACKGROUND: The endocytic reabsorption of proteins in the proximal tubule requires a complex machinery and defects can lead to tubular proteinuria. The precise mechanisms of endocytosis and processing of receptors and cargo are incompletely understoo
Autor:
Katharina F Sonnen, Phong D. Nguyen, Jeroen Bakkers, Veronique E M van der Velden, Hessel Honkoop
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
Development (Cambridge), 148(18). Company of Biologists Ltd
article-version (VoR) Version of Record
Development (Cambridge), 148(18). Company of Biologists Ltd
Zebrafish are excellent at regenerating their heart by reinitiating proliferation in pre-existing cardiomyocytes. Studying how zebrafish achieve this holds great potential in developing new strategies to boost mammalian heart regeneration. Neverthele
Autor:
Linsey Stiles, Sylviane Lagarrigue, Ilan Y. Benador, Anne N. Murphy, Gloria A. Benavides, Marc Liesa, Jonathan Wanagat, Georgios Karamanlidis, Laurent Vergnes, Orian S. Shirihai, Victor M. Darley-Usmar, Rebeca Acín-Pérez, Francesca Amati, Michaela Veliova, Arianne Caudal, Ajit S. Divakaruni, Rong Tian, Harold S. Sacks, Karen Reue, Anton Petcherski
Publikováno v:
The EMBO journal, vol 39, iss 13
The EMBO journal, vol. 39, no. 13, pp. e104073
The EMBO Journal
The EMBO journal, vol. 39, no. 13, pp. e104073
The EMBO Journal
Respirometry is the gold standard measurement of mitochondrial oxidative function, as it reflects the activity of the electron transport chain complexes working together. However, the requirement for freshly isolated mitochondria hinders the feasibil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c0f6badb31cd697d71fe88a14ec025
https://escholarship.org/uc/item/3w97g9bj
https://escholarship.org/uc/item/3w97g9bj
Autor:
Francesca Amati, Enrique Calvo, Sara Cogliati, José Antonio Enríquez, Pablo Hernansanz-Agustín, Nadia Mercader, Carolina García-Poyatos, Jesús Vázquez, Ricardo Magni, Sylviane Lagarrigue, Xavier Langa, Marius Botos
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
EMBO Reports
EMBO reports, vol. 21, no. 7, pp. e50287
Digibug. Repositorio Institucional de la Universidad de Granada
Consejo Superior de Investigaciones Científicas (CSIC)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
García-Poyatos, Carolina; Cogliati, Sara; Calvo, Enrique; Hernansanz-Agustín, Pablo; Lagarrigue, Sylviane; Magni, Ricardo; Botos, Marius; Langa, Javier; Amati, Francesca; Vázquez, Jesús; Mercader, Nadia; Enríquez, José Antonio (2020). Scaf1 promotes respiratory supercomplexes and metabolic efficiency in zebrafish. EMBO reports, 21(7), e50287. EMBO press 10.15252/embr.202050287
Instituto de Salud Carlos III (ISCIII)
EMBO Reports
EMBO reports, vol. 21, no. 7, pp. e50287
Digibug. Repositorio Institucional de la Universidad de Granada
Consejo Superior de Investigaciones Científicas (CSIC)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
García-Poyatos, Carolina; Cogliati, Sara; Calvo, Enrique; Hernansanz-Agustín, Pablo; Lagarrigue, Sylviane; Magni, Ricardo; Botos, Marius; Langa, Javier; Amati, Francesca; Vázquez, Jesús; Mercader, Nadia; Enríquez, José Antonio (2020). Scaf1 promotes respiratory supercomplexes and metabolic efficiency in zebrafish. EMBO reports, 21(7), e50287. EMBO press 10.15252/embr.202050287
The oxidative phosphorylation (OXPHOS) system is a dynamic system in which the respiratory complexes coexist with superassembled quaternary structures called supercomplexes (SCs). The physiological role of SCs is still disputed. Here, we used zebrafi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24773ac5d50874a744edffb1e3d384d
http://hdl.handle.net/20.500.12105/11124
http://hdl.handle.net/20.500.12105/11124
Autor:
Sempou, Emily, Biasini, Emiliano, Pinzon-Olejua, Alejandro, Harris, David-A., Málaga Trillo, George Edward
BACKGROUND: Prions and amyloid-beta (Abeta) oligomers trigger neurodegeneration by hijacking a poorly understood cellular signal mediated by the prion protein (PrP) at the plasma membrane. In early zebrafish embryos, PrP-1-dependent signals control c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3932::910bf7dfa2d7e44c0f7079f33d57515d
https://hdl.handle.net/20.500.12866/5160
https://hdl.handle.net/20.500.12866/5160