Výsledky vyhledávání - "Zebrabärbling"

Loss of function of eukaryotic translation elongation factor 2b (eef2b) leads to cardiac hypertrophy in zebrafish

Autor: Krattenmacher, Diana

In cardiomyocytes, elevated neurohormonal stimulation or mechanical stress mainly led to an increase in cell size and thus cardiac hypertrophy. This might initially enable the myocytes to increase their work output and, thereby, transiently improve c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1066e82bb6e7ce2068d1e3d6213f3d

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Die Rolle von ankrd1b in der Tbx20 vermittelten Signalkaskade während der Entwicklung und Regeneration des Herzens

Autor: Schaller, Benedikt

Der Verlust an Myokardgewebe nach einem Herzinfarkt kann schwerwiegende Komplikationen wie Arrhythmien und Herzinsuffizienz zur Folge haben. Besonders Letztere stellt aufgrund ihrer hohen Morbidität und Mortalität nach wie vor ein großes Problem f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dbd31f3386c555c994e517238ac414f

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The Role of BMP signaling in DNA-damage responses during zebrafish heart regeneration

Autor: Sun, Guoxin

The cardiomyocytes of zebrafish can regenerate in case of necrosis. Several studies have shown that the Bone morphogenetic signaling pathway (BMP signaling) is involved in the process of zebrafish heart regeneration. To identify candidate mediators o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a331e9bcc01454ee31fae970abab1d4

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Dissertation/ Thesis

Der Einfluss von Tnap auf die Zahnentwicklung im Zebrafisch (Danio rerio)

Autor: Riekert, Elisa

Aufgrund mangelnder Aktivität der Gewebe-unspezifischen Phosphatase (tissue-nonspecific alkaline phosphatase, TNAP) kommt es zum Krankheitsbild der Hypophosphatasie (HPP). Neben skelettalen und neuronalen Symptomen leiden Patienten mit HPP häufig a

Externí odkaz: https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/28740
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-287406
https://opus.bibliothek.uni-wuerzburg.de/files/28740/Riekert_Elisa_Tnap.pdf

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Human α-defensin-6 neutralizes clostridioides difficile toxins TcdA and TcdB by direct binding

Autor: Barthold, Lara, Heber, Sebastian, Schmidt, Christoph Q., Gradl, Marion, Weidinger, Gilbert, Barth, Holger, Fischer, Stephan, Kudryashov, Dmitri S., Kudryashova, Elena

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4509

Rising incidences and mortalities have drawn attention to Clostridioides difficile infections (CDIs) in recent years. The main virulence factors of this bacterium are the exotoxins TcdA and TcdB, which glucosylate Rho-GTPases and thereby inhibit Rho/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9493127c8bb8022b73ea506c3e3889fd

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The influence of Tnap on tooth development in zebrafish (Danio rerio)

Autor: Riekert, Elisa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83fe2ffd0e41a60fd957c41e66e88aeb
https://doi.org/10.25972/OPUS-28740

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Long-chain acyl-carnitines interfere with mitochondrial ATP production leading to cardiac dysfunction in zebrafish

Autor: Bernd M. Gahr, Wolfgang Rottbauer, Steffen Just, Deung-Dae Park, Julia Krause, Tanja Zeller

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 8468, p 8468 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16

In the human heart, the energy supplied by the production of ATP is predominately accomplished by ß-oxidation in mitochondria, using fatty acids (FAs) as the primary fuel. Long-chain acylcarnitines (LCACs) are intermediate forms of FA transport that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdea570cbd2f656f6e948ac53c18d925

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Identification and Tissue-Specific Characterization of Novel SHOX-Regulated Genes in Zebrafish Highlights SOX Family Members Among Other Genes

Autor: Sabrina Diebold, Gudrun A. Rappold, Jasmin Gogel, Ralph Roeth, Sandra Hoffmann, David Hassel, Steffen Just

Publikováno v: Frontiers in Genetics
Frontiers in Genetics, Vol 12 (2021)

SHOX deficiency causes a spectrum of clinical phenotypes related to skeletal dysplasia and short stature, including Léri-Weill dyschondrosteosis, Langer mesomelic dysplasia, Turner syndrome, and idiopathic short stature. SHOX controls chondrocyte pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045c07715d3696dd73d9a8b3c08d1204
https://doi.org/10.3389/fgene.2021.688808

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Dissecting the molecular mechanisms of Bmp signaling in zebrafish heart regeneration

Autor: Redaelli, Simone

Background: In contrast to mammals, zebrafish display a remarkable capability to heal heart injuries in a scar-free fashion and to replenish lost myocardial tissue. In zebrafish, upon cardiac damage spared cardiomyocytes located at the wound border d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820bcaf955af0f8437f05d1b0995e03d

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