Zobrazeno 1 - 10
of 20
pro vyhledávání: '"ZeLong Cui"'
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35368- (2024)
Background: Several transcription factors and co-factors are encoded by the RFX (Regulatory Factor X) family (RFX1-8) and associated genes (RFXAP and RFXANK). Increasing evidence suggests that the RFX family and associated genes are involved in the d
Externí odkaz:
https://doaj.org/article/ac678ac1365049dcb42d66e496c24440
Autor:
Xiaolin Yin, Minran Zhou, Lu Zhang, Yue Fu, Man Xu, Xiaoming Wang, Zelong Cui, Zhenxing Gao, Miao Li, Yuting Dong, Huimin Feng, Sai Ma, Chunyan Chen
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-9 (2022)
Abstract The blast crisis (BC) is the final deadly phase of chronic myeloid leukemia (CML), which remains a major challenge in clinical management. However, the underlying molecular mechanism driving blastic transformation remains unclear. Here, we s
Externí odkaz:
https://doaj.org/article/5189553ae60f4a24903bf887492cfc10
Autor:
Guangcai Zhong, Chong Guo, Yangli Shang, Zelong Cui, Minran Zhou, Mingshan Sun, Yue Fu, Lu Zhang, Huimin Feng, Chunyan Chen
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Background: Pyroptosis, a programmed cell death (PCD) with highly inflammatory form, has been recently found to be associated with the origin of hematopoietic malignancies. Long noncoding RNA (lncRNA) had emerged as an essential mediator to regulate
Externí odkaz:
https://doaj.org/article/9362ba32ef3540a0bad815a0c949afc6
Autor:
Zelong Cui, Yue Fu, Zongcheng Yang, Zhenxing Gao, Huimin Feng, Minran Zhou, Lu Zhang, Chunyan Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Ferroptosis is a widespread form of programmed cell death. The environment of cancer cells makes them vulnerable to ferroptosis, including AML cells, yet the specific association between ferroptosis and AML outcome is little known. In this study, we
Externí odkaz:
https://doaj.org/article/cedbb3a23a8d4c30b985312ac1afaf22
Autor:
Minran Zhou, Xiaolin Yin, Lixin Zheng, Yue Fu, Yue Wang, Zelong Cui, Zhenxing Gao, Xiaoming Wang, Tao Huang, Jihui Jia, Chunyan Chen
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundChronic myeloid leukemia (CML) is a malignant clonal proliferative disease. Once it progresses into the phase of blast crisis (CML-BP), the curative effect is poor, and the fatality rate is extremely high. Therefore, it is urgent to explore
Externí odkaz:
https://doaj.org/article/1f969a2297e540deb040673ad0e1b975
Publikováno v:
Biomolecules & Biomedicine, Vol 21, Iss 1 (2021)
Pancreatic cancer (PCC) is a common malignant tumor of the digestive system that is resistant to traditional treatments and has an overall 5-year survival rate of
Externí odkaz:
https://doaj.org/article/9ec58549339042eeb0890c6b7bfe0ddc
Autor:
Yue Fu, Man Xu, Zelong Cui, Zongcheng Yang, Zhiyong Zhang, Xiaolin Yin, Xiangnan Huang, Minran Zhou, Xiaoming Wang, Chunyan Chen
Publikováno v:
EBioMedicine, Vol 52, Iss , Pp - (2020)
Background: Acute myeloid leukaemia (AML) is a malignant haematological tumour with high heterogeneity and mortality. A reliable prognostic assessment is critical for treatment strategies. However, the current prognostic evaluation system of AML is i
Externí odkaz:
https://doaj.org/article/304ce0aa6f4a46ab83b251fbffc3c047
Publikováno v:
Journal of International Medical Research, Vol 47 (2019)
Objective This study was performed to introduce our surgical strategy and experience in applying a repeated reverse sural fasciocutaneous flap (RSFF) to repair large areas of tibial exposure. Methods During a 3-year period, 10 patients with a large a
Externí odkaz:
https://doaj.org/article/86c7586fd904497e9f15f41877cd0487
The new mitochondrial uncoupler BAM15 induces ROS production for treatment of acute myeloid leukemia
Publikováno v:
Biochemical pharmacology. 198
Acute myeloid leukemia (AML) is a malignant proliferative disease of myeloid hematopoietic origin and cannot be treated appropriately at present. This is due to the fact that leukemia cells are not sensitive to some of the traditional chemotherapy dr
Autor:
Xiaoming Wang, Xiaolin Yin, Minran Zhou, Chunyan Chen, Yue Fu, Lixin Zheng, Tao Huang, Yue Wang, Jihui Jia, Zelong Cui, Zhenxing Gao
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
BackgroundChronic myeloid leukemia (CML) is a malignant clonal proliferative disease. Once it progresses into the phase of blast crisis (CML-BP), the curative effect is poor, and the fatality rate is extremely high. Therefore, it is urgent to explore