Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ze-qing Pu"'
Autor:
Ze-qing Pu, Tian-fu Yu, Dong Liu, Cheng-wen Jin, Esha Sadiq, Xiaofei Qiao, Xiaojie Li, Yuxuan Chen, Jinsong Zhang, Mingzhong Tian, Siying Li, Ru-xing Zhao, Xiang-dong Wang
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Under adverse conditions, such as sustained or chronic hyperglycemia or hyperlipidemia, ROS (reactive oxygen species) or/and ER-stress (endoplasmic reticulum stress) will be induced in pancreatic β cells. ROS or ER-stress damages β-cells e
Externí odkaz:
https://doaj.org/article/9782f4b6ceb7453086a740ff701d3c2b
Autor:
Dong Liu, Yuantao Liu, Chen Zong, Tian‐fu Yu, Esha Sadiq, Jie Cheng, Ze‐qing Pu, Yuchao Zhang, Xiangdong Wang, Xiao Yu, Ruxing Zhao, Cheng‐wen Jin, Dandan Qin, Xia Li, Jicui Chen, Hanse Pablick Patherny Lobo Mouguegue, Jing-Yu Lin, Qingbo Guan
Publikováno v:
Journal of Cellular and Molecular Medicine
Sustained hyperglycaemia and hyperlipidaemia incur endoplasmic reticulum stress (ER stress) and reactive oxygen species (ROS) overproduction in pancreatic β‐cells. ER stress or ROS causes c‐Jun N‐terminal kinase (JNK) activation, and the activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c998067b9331388ff92e5634b301b9
https://doi.org/10.1111/jcmm.16028
https://doi.org/10.1111/jcmm.16028
Autor:
Mingzhong Tian, Xiaojie Li, Cheng‐wen Jin, Siying Li, Tian‐fu Yu, Jinsong Zhang, Ze‐qing Pu, Dong Liu, Xiaofei Qiao, Esha Sadiq, Ruxing Zhao, Yuxuan Chen, Xiangdong Wang
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-13 (2021)
Cell Death Discovery
Cell Death Discovery
Under adverse conditions, such as sustained or chronic hyperglycemia or hyperlipidemia, ROS (reactive oxygen species) or/and ER-stress (endoplasmic reticulum stress) will be induced in pancreatic β cells. ROS or ER-stress damages β-cells even leads
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9044fae3da81663f788bb2de1d111f
https://doi.org/10.1038/s41420-021-00521-0
https://doi.org/10.1038/s41420-021-00521-0
Autor:
Chen Zong, Cong Yu, Xiangdong Wang, Yuchao Zhang, Dong Liu, Yuantao Liu, Peng Gao, Xia Li, Y. Yang, Ze‐qing Pu, Dandan Qin, Jicui Chen
Publikováno v:
Journal of Cellular and Molecular Medicine
Nuclear receptor subfamily 4 group A member 1 (NR4A1) is an orphan nuclear receptor with diverse functions. It has been reported that NR4A1, as a transcriptional activator, is implicated in glucose and lipid metabolism. The aim of this study was to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c67eb23bc7aaa419340906057652a62
https://doi.org/10.1111/jcmm.13715
https://doi.org/10.1111/jcmm.13715
Autor:
Chen Zong, Yuchao Zhang, Dandan Qin, Fangyu Xie, Xiangdong Wang, Dong Liu, Yuantao Liu, Ze‐qing Pu, Xia Li, Feng Han, Y. Yang
Publikováno v:
Life Sciences. 203:225-232
Aims Our previous study showed that NR4A1 protects against oxidative stress-induced cell apoptosis. However, the targets downstream of NR4A1 are incompletely known. Glutathione peroxidase 1 (GPX1) is the most common antioxidant enzyme in the glutathi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80085a9b5fed8e8720c1b38878f66a3a
https://doi.org/10.1016/j.lfs.2018.04.027
https://doi.org/10.1016/j.lfs.2018.04.027
Autor:
Peng Gao, Sumei Lu, Dandan Qin, Xia Li, Yuchang Fu, Yuchao Zhang, Y. Yang, Ze‐qing Pu, Qingbo Guan, Xiangdong Wang, Jicui Chen, Cong Yu, Yuantao Liu, Chen Zong
Publikováno v:
Cellular signalling. 35
Pancreatic β-cells often face endoplasmic reticulum stress and/or ROS-associated oxidative stress under adverse conditions. Our previous work has verified that NR4A1 protects pancreatic β-cells from ER-stress induced apoptosis. However, It remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba8e813157cce17af4f1508c8f3183b
https://pubmed.ncbi.nlm.nih.gov/28342843
https://pubmed.ncbi.nlm.nih.gov/28342843