Regulation of intrinsic apoptosis in cycloheximide-treated macrophages by the Sichuan human strain of Chinese Leishmania isolates

Autor: Qiwei Chen, Jie Luo, Jin Zeng, Dali Chen, Ze-Ying Yu, Chen Song, Jian-Ping Chen, Shun-Li Wang, Junrong Zhang, Chen Zhang

Publikováno v: Acta Tropica. 153:101-110

Leishmania spp. are able to survive and proliferate inside mammals' mononuclear phagocytes, causing Leishmaniasis. Previous studies have noted that the regulation of apoptosis in host cells by these parasites may contribute to their ability to evade

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda83af2d09b4493a6b5e785be3c91af
https://doi.org/10.1016/j.actatropica.2015.10.010

Down-regulated expression of IKZF1 mRNA in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

Autor: Xuejun Zhang, Ting-Meng Pan, Yujun Sheng, Yi-Lin Cheng, Wen-Long Hu, Sen Yang, Yong Cui, Jinping Gao, Caifeng He, Yang-Sheng Liu, Xianyong Yin, Pei-Guang Wang, Sha Yao, Wen-Sheng Lu, Xianbo Zuo, Ze-ying Yu, Yun Li, Jianwen Han, Liangdan Sun

Publikováno v: Rheumatology International. 31:819-822

Systemic lupus erythematosus (SLE) is a multi-system autoimmune disease with complex genetic inheritance. IKZF1 was established as a new susceptibility gene for SLE in a recent genome-wide association study (GWAS) in Chinese Han population. In order

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc9c0a7513781f6f75d9fcacd574cb4
https://doi.org/10.1007/s00296-010-1576-1

One novel susceptibility locus associate with systemic lupus erythematosus in Chinese Han population

Autor: Jianwen Han, Liangdan Sun, Yujun Sheng, Wen-Sheng Lu, Jian Hu, Yun Li, Yi-Lin Cheng, Xianbo Zuo, Xuejun Zhang, Sha Yao, Ze-Ying Yu, Yong Cui, Sen Yang, Qiang Xu, Jian Li

Publikováno v: Rheumatology international. 33(8)

The aim of the study is to explore additional susceptibility factors for systemic lupus erythematosus (SLE) in Chinese Hans. Based on our previous GWAS of SLE, we performed a multistage replication study involving 3,152 cases and 7,050 controls from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f4baeeb2df358ad5471cc06ee20c02
https://pubmed.ncbi.nlm.nih.gov/23408151

Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC

Autor: Shao-Qiong Xie, Min Li, Wen-Long Hu, Cheng-Yao Zhu, Zhi-Fang Liu, Ting-Meng Pan, Xuejun Zhang, Qiang Xu, Ying Wang, Ling Liang, Sheng-Quan Zhang, Sheng-Xin Xu, Jian-Bin Yu, Jinping Gao, Yu-Qin Liu, Sen Yang, Chaozhao Liang, Wei-Su Wu, Pu-Ling Dong, Jia-Bin Li, Xianyong Yin, Xiuli Wang, Jun Zhu, Xinghua Gao, Xin Zhang, Yong Zhang, Wei-Song Hong, Xiaodong Zheng, Li Sun, Youwen Zhou, Leihong Xiang, Ri-Na Wu, Yongmei Lv, Xiao-Jing Kang, Tianwen Gao, Rong-Ya Yang, Cheng Ni, Huayang Tang, Hui Cheng, Ai-E Xu, Sumin He, Jun Wang, Xiong-Ming Pu, Caifeng He, Liangdan Sun, Min Shen, Hong-Quan Jiang, Kai Li, Gang Chen, Shu-Mei Zhang, Xianfa Tang, Cheng Quan, Hong-Duo Chen, Fengyu Zhang, Yun Li, Yang-Sheng Liu, Da-Yan Hu, Sha Yao, Yang Li, Yunqing Ren, Ying Ye, Ze-ying Yu, Xiao-Dong Wei, Xianbo Zuo, Pan Li, Jianzhong Zhang, Yong-Wei Li

Publikováno v: Nature genetics. 42(7)

We conducted a genome-wide association study of generalized vitiligo in the Chinese Han population by genotyping 1,117 cases and 1,429 controls. The 34 most promising SNPs were carried forward for replication in samples from individuals of the Chines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c63f403dfda1b11db9acc646550252d
https://pubmed.ncbi.nlm.nih.gov/20526339