Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ze-Rong Wang"'
Autor:
Jian-Ping Zhou, Xin Chen, Shan Feng, Shi-Dong Luo, You-Li Pan, Lei Zhong, Pan Ji, Ze-Rong Wang, Shuang Ma, Lin-Li Li, Yu-Quan Wei, Sheng-Yong Yang
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28930 (2011)
Despite many evidences supporting the concept of "oncogene addiction" and many hypotheses rationalizing it, there is still a lack of detailed understanding to the precise molecular mechanism underlying oncogene addiction. In this account, we develope
Externí odkaz:
https://doaj.org/article/038825093e0a42df97fa6d4d8107eca0
Publikováno v:
Chinese Journal of Chemistry. 35:591-595
The discovery that supported gold catalysts can promote CO/H2O-mediated reduction at ambient temperatures is important to chemoselective synthesis and has gained significant attention in recent years. Whether the alternative Pt group metal (PGM) cata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6eabe5cf24fb263324bec88a322c880
https://doi.org/10.1002/cjoc.201600715
https://doi.org/10.1002/cjoc.201600715
Heterogeneous Gold-Catalyzed Selective Semireduction of Alkynes using Formic Acid as Hydrogen Source
Publikováno v:
Advanced Synthesis & Catalysis. 358:1410-1416
A convenient and robust protocol for the selective transfer semireduction of alkynes was developed, using bio-renewable formic acid as the hydrogen source and easily handled supported gold nanoparticles as the catalyst. The catalytic system showed se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d5ae3571aed2c51db24e69d4c0b21e4
https://doi.org/10.1002/adsc.201501183
https://doi.org/10.1002/adsc.201501183
Autor:
Qi-Zheng Sun, Lin-Li Li, Jing-Jing Liu, Ren-Lin Zheng, Ze-Rong Wang, Yong Xu, Wen-Jing Wang, Chun-Hui Zhang, Shengyong Yang
Publikováno v:
Molecular Diversity. 18:403-409
Here, we describe the structural optimization of a known EGFR inhibitor (compound 1) that showed weak off-target activity against RET. Twenty-six analogs of 1 were synthesized. SAR analysis led to the discovery of several compounds that showed consid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95960e406bf772c39b964770b8955372
https://doi.org/10.1007/s11030-014-9508-8
https://doi.org/10.1007/s11030-014-9508-8
Publikováno v:
International Immunopharmacology. 74:105708
Background and aims Soluble E-cadherin (sE-cadherin) has been observed elevated in patients with various diseases, and implicated in the occurrence and development of those diseases. The implications of sE-cadherin in chronic hepatitis C virus (HCV)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f11269e229616b6af43002bbb604ab
https://doi.org/10.1016/j.intimp.2019.105708
https://doi.org/10.1016/j.intimp.2019.105708
Publikováno v:
ChemInform. 47
A convenient and robust protocol for the selective transfer semireduction of alkynes was developed, using bio-renewable formic acid as the hydrogen source and easily handled supported gold nanoparticles as the catalyst. The catalytic system showed se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09063cb938ba8c116fbf3e07461b0cbd
https://doi.org/10.1002/chin.201637058
https://doi.org/10.1002/chin.201637058
Autor:
Huan-Zhang Xie, Shengyong Yang, Hui Zhang, Qi Huang, Lin-Li Li, You-Li Pan, Jun Zou, Ze-Rong Wang, Hai Lan
Publikováno v:
Chemical Biology & Drug Design. 81:175-184
In this investigation, a common feature pharmacophore model of anaplastic lymphoma kinase inhibitors was developed based on several known anaplastic lymphoma kinase inhibitors that were co-crystallized with anaplastic lymphoma kinase. The established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ee42eff03cf41e62bc65c17f7a681bc
https://doi.org/10.1111/cbdd.12084
https://doi.org/10.1111/cbdd.12084
Autor:
Heng-Xiu Yan, Jun Zou, Ze-Rong Wang, Shan Feng, Yang Lingling, Pan Ji, Guo-Bo Li, Qi-Zheng Sun, Shuang Ma, Shengyong Yang
Publikováno v:
European Journal of Medicinal Chemistry. 56:30-38
Aberrant activation of casein kinase 1 (CK1) has been demonstrated to be implicated in the pathogenesis of cancer and various central nervous system disorders. Discovery of CK1 inhibitors has thus attracted much attention in recent years. In this acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d93b85e223ff3d115e6dcb9623211b
https://doi.org/10.1016/j.ejmech.2012.08.007
https://doi.org/10.1016/j.ejmech.2012.08.007
Autor:
Lin-Li Li, Hui Zhang, Pan Ji, Ze-Rong Wang, Jun Zou, Shengyong Yang, Hua-Lin Wan, Jing-Jing Liu, Chuan Cheng
Publikováno v:
Chemical Biology & Drug Design. 80:366-373
Bruton's tyrosine kinase has emerged as a potential target for the treatment for B-cell malignancies and autoimmune diseases. Discovery of Bruton's tyrosine kinase inhibitors has thus attracted much attention recently. In this investigation, we intro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27c706f6d119b73fb8588fbcb945d89a
https://doi.org/10.1111/j.1747-0285.2012.01415.x
https://doi.org/10.1111/j.1747-0285.2012.01415.x
Autor:
Huan-Zhang Xie, Shengyong Yang, Li-Jiao Wang, Chun-Hui Zhang, Jing-Jing Liu, Zhi-Xing Cao, Shuang Ma, Ren-Lin Zheng, Yuquan Wei, Ze-Rong Wang, Bo Wang, Jiao Yang, Lei Zhong, Yong Xu
Publikováno v:
Leukemia. 26:1892-1895
SKLB1028, a novel oral multikinase inhibitor of EGFR, FLT3 and Abl, displays exceptional activity in models of FLT3-driven AML and considerable potency in models of CML harboring Abl mutants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fec89ef5b331c29eb6344fddb8b29c8
https://doi.org/10.1038/leu.2012.67
https://doi.org/10.1038/leu.2012.67