Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Ze-Qin Guo"'
Autor:
Xue Bai, Ze-Qin Guo, Yan-Pei Zhang, Zhen-zhen Fan, Li-Juan Liu, Li Liu, Li-Li Long, Si-Cong Ma, Jian Wang, Yuan Fang, Xin-Ran Tang, Yu-Jie Zeng, Xinghua Pan, De-Hua Wu, Zhong-Yi Dong
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
LKB1 mutations have been associated with primary resistance to immune checkpoint inhibitors in patients with lung cancer. Here the authors show that Lkb1-deficient lung tumors are characterized by defective trafficking and adhesion of T cells and tha
Externí odkaz:
https://doaj.org/article/cfa146b2c3c2474eb58cc188c46ec8b0
Autor:
Xue-Jun Guo, Xiao-Ting Cai, Zi-Xuan Rong, Yan-Pei Zhang, Yu-Xiang Wen, Xue Bai, Jian Wang, Qiang John Fu, Ze-Qin Guo, Li-Li Long, Si-Cong Ma, Xin-Ran Tang, Li Liu, Jian Guan, Zhong-Yi Dong, De-Hua Wu
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Immune checkpoint inhibitor (ICI) therapy combined with conventional therapies is being broadly applied in non-small cell lung cancer (NSCLC) patients. However, the risk of interstitial pneumonitis (IP) following a combined regime
Externí odkaz:
https://doaj.org/article/9b36884ce008485099683e8c140bc2c6
Autor:
Si-Cong Ma, Xue Bai, Xue-Jun Guo, Li Liu, Lu-Shan Xiao, Yan Lin, Jia-Le Tan, Xiao-Ting Cai, Yu-Xiang Wen, Hu Ma, Q. John Fu, Meng-Xin Leng, Yan-Pei Zhang, Li-Li Long, Ze-Qin Guo, De-Hua Wu, Jian-Guo Zhou, Zhong-Yi Dong
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Organ-specific metastatic context has not been incorporated into the clinical practice of guiding programmed death-(ligand) 1 [PD-(L)1] blockade, due to a lack of understanding of its predictive versus prognostic value. We aim at
Externí odkaz:
https://doaj.org/article/24a3b6c7bf874232b58096c5d956a366
Autor:
Dong-Yan Zhang, Qing-Can Sun, Xue-Jing Zou, Yang Song, Wen-Wen Li, Ze-Qin Guo, Shan-Shan Liu, Li Liu, De-Hua Wu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-18 (2020)
Abstract Background Dysregulation of long non-coding RNAs (lncRNAs) is responsible for cancer initiation and development, positioning lncRNAs as not only biomarkers but also promising therapeutic targets for cancer treatment. A growing number of lncR
Externí odkaz:
https://doaj.org/article/fccb56be076f496e8df7d7d123e0709f
Autor:
Si-Cong Ma, Hong-Bo Zhu, Jian Wang, Yan-Pei Zhang, Xue-Jun Guo, Li-Li Long, Ze-Qin Guo, De-Hua Wu, Zhong-Yi Dong, Xue Bai
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeDespite the success of targeted therapy in c-ros oncogene 1 (ROS1)-rearranged cancers, especially non-small cell lung cancer (NSCLC), the clinical significance of ROS1 de novo mutation has not yet been understood. We sought to elucidate the pr
Externí odkaz:
https://doaj.org/article/de34127cd04f47bc8097330ec0dbe84b
Autor:
Si-Cong Ma, Xin-Ran Tang, Li-Li Long, Xue Bai, Jian-Guo Zhou, Zhi-Jiao Duan, Jian Wang, Qiang John Fu, Hong-Bo Zhu, Xue-Jun Guo, Yan-Pei Zhang, Ze-Qin Guo, De-Hua Wu, Zhong-Yi Dong
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Objectives: Clinical benefits of immune-checkpoint blockade (ICB) versus standard chemotherapy have been established in unselected non-small cell lung cancer (NSCLC). However, the response to ICB therapy among patients is heterogeneous in clinical pr
Externí odkaz:
https://doaj.org/article/489c09595f1a41e4ad06be021b54b7d7
Autor:
Zhong-Yi Dong, Zhu Liu, Xue-Jun Guo, Qin Zeng, Ze-Qin Guo, Yuan Fang, Hong-Bo Zhu, Yao-Wei Zhang, Xiu-Ju Du, Sha-Sha Du, De-Hua Wu, Xin-Ran Tang, Jian Wang, Xue Bai, Li Liu
Relationship between CNA level and TMB in (A) MSK pan-cancer non-ICI treated cohort and (B) other three ICI-treated cohorts (MSK NSCLC, SKCM, and Dana-Farber ICI cohort). For each cancer type and each cohort, a plot is shown containing the CNA level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e23d87940ac372bad60b4c260abc7c3
https://doi.org/10.1158/1078-0432.22471932.v1
https://doi.org/10.1158/1078-0432.22471932.v1
Autor:
Zhong-Yi Dong, Xue Bai, De-Hua Wu, Xinghua Pan, Yan Lin, Xiao-Ting Cai, Jia-Le Tan, Xue-Jun Guo, Jian Wang, Meng-Xin Leng, Duan-Duan Han, Li Liu, Li-Juan Liu, Zhenzhen Fan, Yan-Pei Zhang, Ze-Qin Guo, Si-Cong Ma, Li-Li Long
Contradictory characteristics of elevated mutational burden and a “cold” tumor microenvironment (TME) coexist in liver kinase B1 (LKB1)–mutant non–small cell lung cancers (NSCLC). The molecular basis underlying this paradox and strategies tai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f661458a75564cab8b6f595c12ddeaf
https://doi.org/10.1158/0008-5472.c.6514398
https://doi.org/10.1158/0008-5472.c.6514398
Autor:
Zhong-Yi Dong, Zhu Liu, Xue-Jun Guo, Qin Zeng, Ze-Qin Guo, Yuan Fang, Hong-Bo Zhu, Yao-Wei Zhang, Xiu-Ju Du, Sha-Sha Du, De-Hua Wu, Xin-Ran Tang, Jian Wang, Xue Bai, Li Liu
Demographic and clinicopathologic characteristics of three cohorts treated with immune checkpoint inhibitors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754768c874602041d054e3073fcd23dd
https://doi.org/10.1158/1078-0432.22471914.v1
https://doi.org/10.1158/1078-0432.22471914.v1
Autor:
Zhong-Yi Dong, Xue Bai, De-Hua Wu, Xinghua Pan, Yan Lin, Xiao-Ting Cai, Jia-Le Tan, Xue-Jun Guo, Jian Wang, Meng-Xin Leng, Duan-Duan Han, Li Liu, Li-Juan Liu, Zhenzhen Fan, Yan-Pei Zhang, Ze-Qin Guo, Si-Cong Ma, Li-Li Long
Sequences for qPCR primers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbacf69b8a3c8efaee6b9c7f719ae2c
https://doi.org/10.1158/0008-5472.22433565
https://doi.org/10.1158/0008-5472.22433565