Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ze-Ka Chen"'
Autor:
Yan-Jia Luo, Hechen Bao, Andrew Crowther, Ya-Dong Li, Ze-Ka Chen, Dalton S. Tart, Brent Asrican, Libo Zhang, Juan Song
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114140- (2024)
Summary: Women are more vulnerable to stress and have a higher likelihood of developing mood disorders. The serotonin (5HT) system has been highly implicated in stress response and mood regulation. However, sex-dependent mechanisms underlying seroton
Externí odkaz:
https://doaj.org/article/659b0dd519ee4774995ef2c9bb480683
Autor:
Connor M Wander, Ya-Dong Li, Hechen Bao, Brent Asrican, Yan-Jia Luo, Heather A Sullivan, Tzu-Hao Harry Chao, Wei-Ting Zhang, Samantha L Chéry, Dalton S Tart, Ze-Ka Chen, Yen-Yu Ian Shih, Ian R Wickersham, Todd J Cohen, Juan Song
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Alzheimer’s disease (AD) is characterized by a progressive loss of memory that cannot be efficiently managed by currently available AD therapeutics. So far, most treatments for AD that have the potential to improve memory target
Externí odkaz:
https://doaj.org/article/b86bc6cf52144cdf81b7f50dbae489f8
Autor:
Ya-Nan Zhao, Jian-Bo Jiang, Shi-Yuan Tao, Yang Zhang, Ze-Ka Chen, Wei-Min Qu, Zhi-Li Huang, Su-Rong Yang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The neural circuits regulating REM sleep are poorly understood. The authors reveal that GABAergic neurons in the rostromedial tegmental nucleus suppress the onset and maintenance of REM sleep, and that projections of these neurons to the LDT and LH m
Externí odkaz:
https://doaj.org/article/42177e4c3a8c4171bed9398fe88f5092
Autor:
Ze-Ka Chen, Hui Dong, Cheng-Wei Liu, Wen-Ying Liu, Ya-Nan Zhao, Wei Xu, Xiao Sun, Yan-Yu Xiong, Yuan-Yuan Liu, Xiang-Shan Yuan, Bing Wang, Michael Lazarus, Yoan Chérasse, Ya-Dong Li, Fang Han, Wei-Min Qu, Feng-Fei Ding, Zhi-Li Huang
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-15 (2022)
Abstract Physiological rapid eye movement (REM) sleep termination is vital for initiating non-REM (NREM) sleep or arousal, whereas the suppression of excessive REM sleep is promising in treating narcolepsy. However, the neuronal mechanisms controllin
Externí odkaz:
https://doaj.org/article/7ab8b4c0d7e84170a9272b6c8bcffd23
Autor:
Ze-Ka Chen, Xiang-Shan Yuan, Hui Dong, Yong-Fang Wu, Gui-Hai Chen, Miao He, Wei-Min Qu, Zhi-Li Huang
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
The GABAergic neurons in the lateral pontine tegmentum (LPT) play key roles in the regulation of sleep and locomotion. The dysfunction of the LPT is related to neurological disorders such as rapid eye movement sleep behavior disorder and ocular flutt
Externí odkaz:
https://doaj.org/article/47c8f256e61b44fe9e38541e1370ad37
Autor:
Ya-Nan Zhao, Jian-Bo Jiang, Shi-Yuan Tao, Yang Zhang, Ze-Ka Chen, Wei-Min Qu, Zhi-Li Huang, Su-Rong Yang
Publikováno v:
Nature communications. 13(1)
Rapid eye movement (REM) sleep disturbances are prevalent in various psychiatric disorders. However, the neural circuits that regulate REM sleep remain poorly understood. Here, we found that in male mice, optogenetic activation of rostromedial tegmen
Autor:
Hui, Dong, Ze-Ka, Chen, Han, Guo, Xiang-Shan, Yuan, Cheng-Wei, Liu, Wei-Min, Qu, Zhi-Li, Huang
Publikováno v:
Current biology : CB. 32(3)
Patients with Parkinson's disease (PD) suffer from severe sleep disorders. Pathophysiology of the basal ganglia (BG) underlies PD, and the dorsal striatum represents the major input pathway of the BG. However, the roles and mechanisms of the dorsal s
Autor:
Ya-Dong Li, Yan-Jia Luo, Ze-Ka Chen, Luis Quintanilla, Yoan Cherasse, Libo Zhang, Michael Lazarus, Zhi-Li Huang, Juan Song
Publikováno v:
Nature neuroscience. 25(5)
Adult hippocampal neurogenesis plays a critical role in memory and emotion processing, and this process is dynamically regulated by neural circuit activity. However, it remains unknown whether manipulation of neural circuit activity can achieve suffi
Autor:
Hao-Hua Wei, Xiang-Shan Yuan, Wei-Min Qu, Ruixi Li, Ze-Ka Chen, Pei-Pei Chen, Guo-Min Zhou, Zhe Xiang, Zhi-Li Huang
Publikováno v:
Experimental neurology. 343
Arginine vasopressin (AVP) neurons in the hypothalamic supraoptic nucleus (SON) and paraventricular nucleus (PVN) are involved in important physiological behaviors, such as controling osmotic stability and thermoregulation. However, the presynaptic i
Publikováno v:
Hearing research. 401
Vestibular nuclei complex (VN) glutamatergic neurons play a critical role in the multisensory and multimodal processing. The dysfunction of VN leads to a series of vestibular concurrent symptoms, such as disequilibrium, spatial disorientation, autono