Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Ze-Hui Gong"'
Autor:
Ling-Lei Kong, Guo-Lin Shen, Zhi-Yuan Wang, Xiao-Mei Zhuang, Wei-Bin Xiao, Mei Yuan, Ze-Hui Gong, Hua Li
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Thienorphine (TNP) is a novel partial opioid agonist that has completed phase II clinical evaluation as a promising drug candidate for the treatment of opioid dependence. Previous studies have shown that TNP and its glucuronide conjugate (TNP-G) unde
Externí odkaz:
https://doaj.org/article/23dd9e0dc695449cab63adec03644287
Publikováno v:
Neurochemistry International. 99:9-15
Disturbance of glutamate homeostasis is a well-characterized mechanism of neuropathic pain. Vesicular glutamate transporters (VGLUTs) determine glutamate accumulation in synaptic vesicles and their roles in neuropathic pain have been suggested by gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46d7e960409dfac84a3f018dd452f62
https://doi.org/10.1016/j.neuint.2016.05.008
https://doi.org/10.1016/j.neuint.2016.05.008
Autor:
Rui-Bin Su, Xiao-Nan Liang, Yu-lei Li, Jing Peng, Ze-Hui Gong, Huanbai Wang, Gang Yu, Zhi-Ling Zhang
Publikováno v:
Neuropharmacology. 164:107869
Vesicular glutamate transporter 2 (VGLUT2)-which uptakes glutamate into presynaptic vesicles-is a fundamental component of the glutamate neurotransmitter system. Although several lines of evidence from genetically modified mice suggest a possible ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11baaeb73ffdc809bf8eda3e3feb66bd
https://doi.org/10.1016/j.neuropharm.2019.107869
https://doi.org/10.1016/j.neuropharm.2019.107869
Publikováno v:
Brain Research. 1624:515-524
Vesicular glutamate transporters (VGLUTs) control the storage and release of glutamate, which plays a critical role in pain processing. The VGLUT2 isoform has been found to be densely distributed in the nociceptive pathways in supraspinal regions, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6929ceeff69f1f85b79d9125704725ac
https://doi.org/10.1016/j.brainres.2015.08.010
https://doi.org/10.1016/j.brainres.2015.08.010
Publikováno v:
Digestive Diseases and Sciences. 59:2417-2422
Ilaprazole is a novel proton pump inhibitor that has been marketed as an oral therapy for acid-related diseases in China and Korea. This study aimed to compare the gastroprotective effects of intravenous and enteral ilaprazole in rat models. The rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d162034761c1d0933e72ccf2b4788a
https://doi.org/10.1007/s10620-014-3187-2
https://doi.org/10.1007/s10620-014-3187-2
Publikováno v:
Behavioural Pharmacology. 24:653-658
Accumulating evidence suggests that vesicular glutamate transporters (VGLUTs), which control the storage and release of glutamate, may play a role in pain processing. Chicago sky blue 6B (CSB6B), which is structurally related to glutamate, is a compe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1d33e89279ec2ae3f547a4a0045dd7
https://doi.org/10.1097/fbp.0000000000000007
https://doi.org/10.1097/fbp.0000000000000007
Publikováno v:
Journal of Receptors and Signal Transduction. 34:44-47
Our previous study demonstrated that acute and repeated morphine treatment differentially regulated κ-opioid receptor mRNA levels in the rat mesocorticolimbic system. Here, we further investigated the effects of morphine on protein levels of κ-opio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2a271fd4fac1e53ccc25537bf3bea3
https://doi.org/10.3109/10799893.2013.856919
https://doi.org/10.3109/10799893.2013.856919
Autor:
Bin Huang, Yan Song, Meiliang Wang, Xintong Wang, Yanxing Jia, Feng-Ying Zhang, Rui-Bin Su, Gang Yu, Ze-Hui Gong
Publikováno v:
Journal of medicinal chemistry. 59(8)
(-)-Incarvillateine (INCA) is the major antinociceptive component of Incarvillea sinensis, which has been used to treat rheumatism and relieve pain in traditional Chinese medicine. We have developed a concise and general synthetic approach for INCA,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6938a748f3fe13ca55b6e8ae3fdc2f67
https://pubmed.ncbi.nlm.nih.gov/27022999
https://pubmed.ncbi.nlm.nih.gov/27022999
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 2, Iss 2, Pp 174-180 (2012)
Thienorphine (TNP) is a new partial opioid agonist currently developed as a promising drug candidate with the intended clinical indication for the treatment of opioid dependence. The pharmacokinetic profile and biliary excretion of TNP and its glucur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dccb9ec1ee2a77b8f235881d8a57517e
https://doi.org/10.1016/j.apsb.2012.02.007
https://doi.org/10.1016/j.apsb.2012.02.007
Publikováno v:
European Journal of Pharmacology. 607:110-113
We have previously reported that Quercetin 3-O-b- d -apiofuranosyl-(1→2)-[a- l -rhamnopyranosyl-(1→6)]-b- d -glucopyranoside (CTN-986), a potential antidepressant extracted from glandless cottonseeds, exerted a notable antidepressant-like effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d44ceb11d437c9d8767d44948d1865
https://doi.org/10.1016/j.ejphar.2008.12.052
https://doi.org/10.1016/j.ejphar.2008.12.052