Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Ze-Hong Miao"'
Autor:
Li‐Min Wang, Pingyuan Wang, Xiao‐Min Chen, Hui Yang, Shan‐Shan Song, Zilan Song, Li Jia, Hua‐Dong Chen, Xu‐Bin Bao, Ne Guo, Xia‐Juan Huan, Yong Xi, Yan‐Yan Shen, Xin‐Ying Yang, Yi Su, Yi‐Ming Sun, Ying‐Lei Gao, Yi Chen, Jian Ding, Jing‐Yu Lang, Ze‐Hong Miao, Ao Zhang, Jin‐Xue He
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 3, Pp n/a-n/a (2023)
Abstract Poly‐ADP‐ribose polymerase (PARP) inhibitors (PARPi) have shown great promise for treating BRCA‐deficient tumors. However, over 40% of BRCA‐deficient patients fail to respond to PARPi. Here, we report that thioparib, a next‐generat
Externí odkaz:
https://doaj.org/article/24325773452c46108ba801e5debd9f21
Autor:
Li-Na Zhou, Chaodong Xiong, Yong-Jun Cheng, Shan-Shan Song, Xu-Bin Bao, Xia-Juan Huan, Tong-Yan Wang, Ao Zhang, Ze-Hong Miao, Jin-Xue He
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 32, Iss , Pp 100823- (2022)
Inhibition of the NEDD8-activating enzyme (NAE), the key E1 enzyme in the neddylation cascade, has been considered an attractive anticancer strategy with the discovery of the first-in-class NAE inhibitor, MLN4924. In this study, we identified SOMCL-1
Externí odkaz:
https://doaj.org/article/b631d181d8ac4e6eaba5e0c1b074aaac
Autor:
Ning Zhang, Yu-Nan Tian, Li-Na Zhou, Meng-Zhu Li, Hua-Dong Chen, Shan-Shan Song, Xia-Juan Huan, Xu-Bin Bao, Ao Zhang, Ze-Hong Miao, Jin-Xue He
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-18 (2021)
Abstract Monotherapy with poly ADP-ribose polymerase (PARP) inhibitors results in a limited objective response rate (≤60% in most cases) in patients with homologous recombination repair (HRR)-deficient cancer, which suggests a high rate of resistan
Externí odkaz:
https://doaj.org/article/aa58f0bfd0a740678bf052d1f92375c9
Autor:
Yi Chen, Song-Wei Li, Fang-Zhou Yin, Min Yang, Xia-Juan Huan, Ze-Hong Miao, Xiao-Ming Wang, Yue-Wei Guo
Publikováno v:
Natural Products and Bioprospecting, Vol 11, Iss 1, Pp 73-79 (2020)
Abstract A phytochemical investigation of the EtOH extract of the flowers of Lagerstroemia indica L. led to the isolation and characterization of a new pyrrole alkaloid, named lagerindicine (1), along with four known compounds (2–5). Their structur
Externí odkaz:
https://doaj.org/article/1a0a037f41294675a63ee2710baeed29
Autor:
Qihao Wu, Wen-Ting Chen, Song-Wei Li, Jian-Yu Ye, Xia-Juan Huan, Margherita Gavagnin, Li-Gong Yao, Hong Wang, Ze-Hong Miao, Xu-Wen Li, Yue-Wei Guo
Publikováno v:
Marine Drugs, Vol 17, Iss 1, p 56 (2019)
A detailed chemical investigation of two South China Sea nudibranchs Phyllidiella pustulosa and Phyllidia coelestis, as well as their possible sponge-prey Acanthella cavernosa, led to the isolation of one new nitrogenous cadinane-type sesquiterpenoid
Externí odkaz:
https://doaj.org/article/ef232921ee0d456691cd7fc865356ab3
Autor:
Ying-Qing Wang, Ze-Hong Miao
Publikováno v:
Marine Drugs, Vol 11, Iss 3, Pp 903-933 (2013)
Angiogenesis inhibitors have been successfully used for cancer therapy in the clinic. Many marine-derived natural products and their analogues have been reported to show antiangiogenic activities. Compared with the drugs in the clinic, these agents d
Externí odkaz:
https://doaj.org/article/32c046ccea194c2a8bddf5cf5fb6439b
Autor:
Hong Xin, Ying Kong, Xiaoxiao Jiang, Ke Wang, Xiaoran Qin, Ze-Hong Miao, Yizhun Zhu, Wenfu Tan
Publikováno v:
Journal of Pharmacological Sciences, Vol 122, Iss 4, Pp 299-304 (2013)
Multiple drug resistance (MDR) occurring during chemotherapy is a major obstacle for treatment of cancers using chemotherapeutic drugs; thus, the mechanisms underlying MDR have attracted intensive attention. Many studies have shown that tumor-initiat
Externí odkaz:
https://doaj.org/article/44bef36d8eb64289a974888f435558bf
Autor:
Hong Zhu, Ze-Hong Miao, Min Huang, Jian-Ming Feng, Zhi-Xiang Zhang, Jin-Jian Lu, Yu-Jun Cai, Lin-Jiang Tong, Yu-Fang Xu, Xu-Hong Qian, Jian Ding
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 11, Pp 1226-1234 (2009)
Naphthalimides, particularly amonafide and 2-(2-dimethylamino)-6-thia-2-aza-benzo[def]chrysene-1,3-diones (R16), have been identified to possess anticancer activities and to induce G2-M arrest through inhibiting topoisomerase II accompanied by Chk1 d
Externí odkaz:
https://doaj.org/article/04ca296a405a467da758a9e696d453ac
Autor:
Ze-Hong Miao, Jing-Kang Shen, Jian Ding, Yi Chen, Lin-Jiang Tong, Lan-Ping Ma, Xia-Juan Huan, Jun-Mei Yi, Tao Meng, Ying-Qing Wang, Wei Wang
PDF - 84K, Legends for Supplementary Figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5993ad4e2f9c2bd8ad5bac8c2be322ab
https://doi.org/10.1158/1535-7163.22500784.v1
https://doi.org/10.1158/1535-7163.22500784.v1
Triptolide reduced c-Myc and c-myc mRNA in MDR cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30bf9619e67677e9a1cc6500ad824cbd
https://doi.org/10.1158/1535-7163.22508847
https://doi.org/10.1158/1535-7163.22508847