Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ze-Bo Jiang"'
Autor:
Min Huang, Fang He, Dan Li, Ya-Jia Xie, Ze-Bo Jiang, Ju-Min Huang, Xiao-Ping Zhao, Ali Adnan Nasim, Jun-Hui Chen, Jin-Cai Hou, Xian-Ming Fan, Elaine Lai-Han Leung, Xing-Xing Fan
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-11 (2022)
Abstract A low response rate to immune checkpoint inhibitor (ICI) therapy has impeded its clinical use. As reported previously, an inflamed tumor microenvironment (TME) was directly correlated with patients’ response to immune checkpoint blockade (
Externí odkaz:
https://doaj.org/article/dbfbc594230341c78aed8c4fac9cd1f7
Autor:
Cong Xu, Ze-Bo Jiang, Le Shao, Zi-Ming Zhao, Xing-Xing Fan, Xinbing Sui, Li-Li Yu, Xuan-Run Wang, Ruo-Nan Zhang, Wen-Jun Wang, Ya-Jia Xie, Yi-Zhong Zhang, Xiao-Wen Nie, Chun Xie, Ju-Min Huang, Jing Wang, Jue Wang, Elaine Lai-Han Leung, Qi-Biao Wu
Publikováno v:
Pharmacological Research, Vol 191, Iss , Pp 106739- (2023)
Nearly half of all Asian non-small cell lung cancer (NSCLC) patients harbour epidermal growth factor receptor (EGFR) mutations, and first-generation EGFR tyrosine kinase inhibitors (TKIs) are one of the first-line treatments that have improved the ou
Externí odkaz:
https://doaj.org/article/2d1e9702c6ab455085c9c03e552d064a
Autor:
Elaine Laihan Leung, Huan-Ling Lai, Run-Ze Li, Hu-Dan Pan, Ze-Bo Jiang, Ying Li, Fu-Gang Duan, Jia-Hui Xu, Yi-Zhong Zhang, A-Xi Shi, Chun-Li Wei, Fang-Yuan Zhang, Xiao-Jun Yao, Liang Liu
Publikováno v:
Engineering, Vol 10, Iss , Pp 174-182 (2022)
Secondary amyloid A amyloidosis, a lethal complication, is induced when acute or chronic infection coexists with over-secretion of the serum amyloid A 1 (SAA1) protein and deposition in key internal organs. Previously, using the whole-exome sequencin
Externí odkaz:
https://doaj.org/article/0d700a6845bc4acc9b16ca72efd91a47
Autor:
Ze-Bo Jiang, Ju-Min Huang, Ya-Jia Xie, Yi- Zhong Zhang, Chan Chang, Huan-Ling Lai, Wenjun Wang, Xiao-Jun Yao, Xing-Xing Fan, Qi-Biao Wu, Chun Xie, Mei-Fang Wang, Elaine Lai-Han Leung
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)
Abstract Background Accumulating evidence showed that regulating tumor microenvironment plays a vital role in improving antitumor efficiency. Programmed Death Ligand 1 (PD-L1) is expressed in many cancer cell types, while its binding partner Programm
Externí odkaz:
https://doaj.org/article/1d50b10fa1324da7958784d31a431d00
Autor:
Jia-Xin Li MB, Ju-Min Huang MPhil, Ze-Bo Jiang MPhil, Run-Ze Li PhD, Ao Sun, Elaine Lai-Han Leung PhD, Pei-Yu Yan MD, PhD
Publikováno v:
Integrative Cancer Therapies, Vol 18 (2019)
Conventional methods in treating non–small cell lung cancer contain surgery, chemotherapy, radiotherapy, and targeted therapy, which have various defects. Recently, with the deeper research on tumor immunity, immunotherapy has made the breakthrough
Externí odkaz:
https://doaj.org/article/622118b438a94a22b285817aece42af3
Autor:
Xi Dai, Run-Ze Li, Ze-Bo Jiang, Chun-Li Wei, Lian-Xiang Luo, Xiao-Jun Yao, Guo-Ping Li, Elaine L.-H. Leung
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Honokiol is a natural compound with small molecular structure and extracted from bark of magnolia trees. The biological activities of honokiol include anti-oxidation, anti-inflammation as well as anti-tumor. However, their mechanism remains unknown.
Externí odkaz:
https://doaj.org/article/a29b8e9e08214426ba4e4fb928103295
Publikováno v:
Cellular Physiology and Biochemistry, Vol 33, Iss 2, Pp 375-388 (2014)
Background/Aims: The effects of glycyrrhizin treatment in lung cancer remain undetermined, despite extensive studies of the anti-tumor activities of glycyrrhizin. Methods: Lung adenocarcinoma A549 and NCI-H23 cell lines were used in this study. Cell
Externí odkaz:
https://doaj.org/article/b89bf75ab0404a09bef2b7ae4f689264
Autor:
Run-Yue Huang, Yong-Liang Chu, Qing-Chun Huang, Xiu-Min Chen, Ze-Bo Jiang, Xian Zhang, Xing Zeng
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93690 (2014)
18β-Glycyrrhetinic acid (18β-GA) is a bioactive component of licorice. The anti-cancer activity of 18β-GA has been studied in many cancer types, whereas its effects in lung cancer remain largely unknown. We first showed that 18β-GA effectively su
Externí odkaz:
https://doaj.org/article/f60ccc0fabba47448317d7de273af2b6
Autor:
Hudan Pan, Fang-Yuan Zhang, Elaine Lai-Han Leung, Jiahui Xu, Chunli Wei, Xiao-Jun Yao, Ze-Bo Jiang, A-Xi Shi, Yi-Zhong Zhang, Huan-Ling Lai, Fu-Gang Duan, Run-Ze Li, Ying Li, Liang Liu
Publikováno v:
Engineering. 10:174-182
Secondary amyloid A amyloidosis, a lethal complication, is induced when acute or chronic infection coexists with over-secretion of the serum amyloid A 1 (SAA1) protein and deposition in key internal organs. Previously, using the whole-exome sequencin
Autor:
Chun Xie, Min Huang, Qibiao Wu, Elaine Lai-Han Leung, Xiao-Jun Yao, Yi-Zhong Zhang, Ju-Min Huang, Ze-Bo Jiang, Xing-Xing Fan, Liang Liu, Yupo Ma, Pei-Yu Yan, Ya-Jia Xie, Cong Xu, Wen-Jun Wang, Xuan-Run Wang, Pei Liu
Publikováno v:
Cancer Letters. 515:36-48
Upregulated expression of immune checkpoint molecules correlates with exhausted phenotype and impaired function of cytotoxic T cells to evade host immunity. By disrupting the interaction of PD-L1 and PD1, immune checkpoint inhibitors can restore immu