Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ze‐Hua Zuo"'
Autor:
Ze‐Hua Zuo, Yan‐Ping Yu, Bao‐Guo Ren, Silvia Liu, Joel Nelson, Zhou Wang, Junyan Tao, Tirthadipa Pradhan‐Sundd, Rohit Bhargava, George Michalopoulos, Qi Chen, Jun Zhang, Deqin Ma, Arjun Pennathur, James Luketich, Paul Satdarshan Monga, Michael Nalesnik, Jian‐Hua Luo
Publikováno v:
Hepatology Communications, Vol 6, Iss 1, Pp 209-222 (2022)
Chromosome rearrangement is one of the hallmarks of human malignancies. Gene fusion is one of the consequences of chromosome rearrangements. In this report, we show that gene fusion between solute carrier family 45 member 2 (SLC45A2) and alpha‐meth
Externí odkaz:
https://doaj.org/article/fb5117d3895a4b99b7233fb8a5c6548c
Autor:
Ze-Hua Zuo, Silvia Liu, Deqin Ma, Joel B. Nelson, James D. Luketich, Paul Satdarshan Monga, George K. Michalopoulos, Qi Chen, Jianhua Luo, Yanping Yu, Rohit Bhargava, Baoguo Ren, Arjun Pennathur, Michael A. Nalesnik, Jun Zhang, Junyan Tao, Tirthadipa Pradhan-Sundd, Zhou Wang
Publikováno v:
Hepatology Communications, Vol 6, Iss 1, Pp 209-222 (2022)
Hepatology Communications
Hepatology Communications
Chromosome rearrangement is one of the hallmarks of human malignancies. Gene fusion is one of the consequences of chromosome rearrangements. In this report, we show that gene fusion between solute carrier family 45 member 2 (SLC45A2) and alpha-methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842ecffab914d4727da49ac03bf0985e
https://doi.org/10.1002/hep4.1724
https://doi.org/10.1002/hep4.1724
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009068 (2020)
PLoS Genetics
PLoS Genetics
Diphthamide is a unique post-translationally modified histidine residue (His715 in all mammals) found only in eukaryotic elongation factor-2 (eEF-2). The biosynthesis of diphthamide represents one of the most complex modifications, executed by protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cffa06431989884ec76f1e2880660d0
https://doaj.org/article/6ac3396df3a045af88f197e3358f5047
https://doaj.org/article/6ac3396df3a045af88f197e3358f5047
Autor:
Silvia Liu, Yan P. Yu, Ze-Hua Zuo, Satdatshan Monga, Joel B. Nelson, George C. Tseng, Zhang-Hui Chen, George K. Michalopoulos, Jianhua Luo
Publikováno v:
Nature biotechnology
Specifically targeting genomic rearrangements and mutations in tumor cells has remained an elusive goal in cancer therapy. Here, we use Cas9-based genome editing to introduce the gene for the pro-drug converting enzyme ‘herpes simplex virus type 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002a8a472ef0ddc2b30799e3084d384b
https://doi.org/10.1038/nbt.3843
https://doi.org/10.1038/nbt.3843
Publikováno v:
Molecular Carcinogenesis. 56:315-324
Cellular stress response 1 (CSR1) is a tumor suppressor gene that plays an important role in regulating cell death. In this report, we show that the N-terminus of CSR1 interacts with splicing factor 3A, subunit 3 (SF3A3). The SF3A3 binding motif was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73f91ef9468ca757bfe518dde994932a
https://doi.org/10.1002/mc.22494
https://doi.org/10.1002/mc.22494
Autor:
Inka Sastalla, Shihui Liu, Ze-Hua Zuo, Yuesheng Li, Stephen H. Leppla, Toren Finkel, Mehdi Pirooznia, Yusuke Sekine, Jie Liu, Chengyu Liu, Ji Yong Jang
Publikováno v:
Cell Host Microbe
Bacteria and their toxins are associated with significant human morbidity and mortality. While a few bacterial toxins are well characterized, the mechanism of action for most toxins has not been elucidated, thereby limiting therapeutic advances. One
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1201453e4dfe518acb479e8759acd8d3
https://doi.org/10.1016/j.chom.2020.05.012
https://doi.org/10.1016/j.chom.2020.05.012
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e65ffa3c37013adc27fb35e960159bc
https://doi.org/10.1096/fasebj.2020.34.s1.04034
https://doi.org/10.1096/fasebj.2020.34.s1.04034
Publikováno v:
The American Journal of Pathology. 185:1834-1845
Fusion transcript formation is one of the fundamental mechanisms that drives the development of prostate cancer. Because of the advance of high-throughput parallel sequencing, many fusion transcripts have been discovered. However, the discovery rate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c55435ec1894e6e0caae858f391ee4
https://doi.org/10.1016/j.ajpath.2015.03.008
https://doi.org/10.1016/j.ajpath.2015.03.008
Autor:
Jian-Zhong Tang, Ze-Hua Zuo, Xiang-Jun Kong, Michael Steiner, Zhinan Yin, Jo K. Perry, Tao Zhu, Dong-Xu Liu, Peter E. Lobie
Publikováno v:
Endocrine reviews. 30(7)
Increased signal transducer and activator of transcription (STAT)-5 activation has been reported in various malignancies including mammary carcinoma. However, it is only recently that potentially distinct roles of STAT5A and STAT5B in neoplasia have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4253c7570ac21dcb36ebf3ebfd1b26a9
https://pubmed.ncbi.nlm.nih.gov/28199519
https://pubmed.ncbi.nlm.nih.gov/28199519
Autor:
Joel B. Nelson, Yan P. Yu, Zhong-Liang Zheng, Jianhua Luo, Rui Chen, Yu-Chen Han, George C. Tseng, Ze-Hua Zuo
Publikováno v:
The Journal of Pathology. 230:184-193
Metallothioneins (MTs) are a group of metal binding proteins thought to play a role in the detoxification of heavy metals. Here we showed by microarray and validation analyses that MT1h, a member of MT, is down-regulated in many human malignancies. L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7cd5435fe6f6ae4fd890132a4b21945
https://doi.org/10.1002/path.4169
https://doi.org/10.1002/path.4169