Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Ze'ev Paroush"'
Publikováno v:
PLoS Genetics, Vol 13, Iss 6, p e1006860 (2017)
Dorsal closure (DC) is a developmental process in which two contralateral epithelial sheets migrate to seal a large hole in the dorsal ectoderm of the Drosophila embryo. Two signaling pathways act sequentially to orchestrate this dynamic morphogeneti
Externí odkaz:
https://doaj.org/article/58bfa569dbe849a38746c0ee4c2246e3
Autor:
Einat Cinnamon, Rami Makki, Annick Sawala, Leah P Wickenberg, Gary J Blomquist, Claus Tittiger, Ze'ev Paroush, Alex P Gould
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1006154 (2016)
Cell growth and proliferation depend upon many different aspects of lipid metabolism. One key signaling pathway that is utilized in many different anabolic contexts involves Phosphatidylinositide 3-kinase (PI3K) and its membrane lipid products, the P
Externí odkaz:
https://doaj.org/article/9bbc873bb4fa4b63b1e7fe91e16fc248
Publikováno v:
Molecular Systems Biology, Vol 7, Iss 1, Pp 1-9 (2011)
Abstract Phosphorylation of the mitogen‐activated protein kinase (MAPK) is essential for its enzymatic activity and ability to control multiple substrates inside a cell. According to the current models, control of MAPK phosphorylation is independen
Externí odkaz:
https://doaj.org/article/8eab5885bcd4463baaca36b3c98224b8
Autor:
Marta Forés, Leiore Ajuria, Núria Samper, Sergio Astigarraga, Claudia Nieva, Rona Grossman, Sergio González-Crespo, Ze'ev Paroush, Gerardo Jiménez
Publikováno v:
PLoS Genetics, Vol 11, Iss 1, p e1004902 (2015)
Receptor Tyrosine Kinase (RTK) signaling pathways induce multiple biological responses, often by regulating the expression of downstream genes. The HMG-box protein Capicua (Cic) is a transcriptional repressor that is downregulated in response to RTK
Externí odkaz:
https://doaj.org/article/df9a41c48481449fa41a6cb4b62a5d3f
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002632 (2012)
Drosophila melanogaster Held Out Wings (HOW) is a conserved RNA-binding protein (RBP) belonging to the STAR family, whose closest mammalian ortholog Quaking (QKI) has been implicated in embryonic development and nervous system myelination. The HOW RB
Externí odkaz:
https://doaj.org/article/c665d74f7ee14820b73c2f9b818239c4
Autor:
Shaked Bar-Cohen, María Lorena Martínez Quiles, Alexey Baskin, Ruba Dawud, Barbara H. Jennings, Ze'ev Paroush
Publikováno v:
Development.
The cell cycle depends on a sequence of steps that are triggered and terminated via the synthesis and degradation of phase-specific transcripts and proteins. While much is known about how stage-specific transcription is activated, less is understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10196f55ddb954585a168b19a7b1641b
https://doi.org/10.1242/dev.201041
https://doi.org/10.1242/dev.201041
Autor:
Rotem Lange, Allan Bar-Sinai, Adi Salzberg, Ze'ev Paroush, Shaked Bar-Cohen, Tatyana Kushnir, David Engelberg, Navit Mooshayef, Helit Rozen
Publikováno v:
Genetics. 214:109-120
Excessive RTK signaling, often caused by activating mutations in Ras, Raf and/or MEK, occurs in most human tumors. Intriguingly, confirmed cancer-driver mutations in the downstream effector kinase, ERK, have not been reported. To test if... Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1c16c338521ea040fb0d3440080c2f9
https://doi.org/10.1534/genetics.119.302794
https://doi.org/10.1534/genetics.119.302794
Autor:
Shaked Bar-Cohen, Ze’ev Paroush
The cell cycle depends on a sequence of steps that are triggered and terminated via the synthesis and degradation of phase-specific transcripts and proteins. While much is known about how stage-specific transcription is activated, less is understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc5496f7cd52ec1bb6f8139873c50ac3
https://doi.org/10.1101/2022.02.22.481413
https://doi.org/10.1101/2022.02.22.481413
Autor:
Tatyana, Kushnir, Shaked, Bar-Cohen, Navit, Mooshayef, Rotem, Lange, Allan, Bar-Sinai, Helit, Rozen, Adi, Salzberg, David, Engelberg, Ze'ev, Paroush
Publikováno v:
Genetics
Receptor tyrosine kinase signaling plays prominent roles in tumorigenesis, and activating oncogenic point mutations in the core pathway components Ras, Raf, or MEK are prevalent in many types of cancer. Intriguingly, however, analogous oncogenic muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49a3db117bfe42666f0959e67cc26f7a
https://pubmed.ncbi.nlm.nih.gov/31740452
https://pubmed.ncbi.nlm.nih.gov/31740452
Autor:
María José Andreu, Gerardo Jiménez, Ze'ev Paroush, Núria Samper, Sergio González-Crespo, Aikaterini Papagianni, Marta Forés, Shuonan He, Julia Zeitlinger, Nina Koenecke, Wanqing Shao
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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The HMG-box protein Capicua (Cic) is a conserved transcriptional repressor that functions downstream of receptor tyrosine kinase (RTK) signaling pathways in a relatively simple switch: In the absence of signaling, Cic represses RTK-responsive genes b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b5523c81005e9b4902482e46265dbc
http://hdl.handle.net/10261/174133
http://hdl.handle.net/10261/174133