Výsledky vyhledávání - "Zdenka Vanourkova"

Akademický článek

Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats

Autor: Věra Čertíková Chábová, Petr Kujal, Zdeňka Vaňourková, Petra Škaroupková, Janusz Sadowski, Elzbieta Kompanowska-Jezierska, Vladimír Tesař, Bruce Hammock, John Imig, Hana Maxová, Luděk Červenka, Ivana Vaněčková

Publikováno v: Kidney & Blood Pressure Research, Vol 44, Iss 6, Pp 1493-1505 (2019)

Introduction: Previous studies in Ren-2 transgenic hypertensive rats (TGR) after 5/6 renal ablation (5/6 NX) have shown that besides pharmacological blockade of the renin-angiotensin system (RAS) also increasing kidney tissue epoxyeicosatrienoic acid

Externí odkaz: https://doaj.org/article/e825f8319c354c929117bd918f0dbf1d

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Akademický článek

Renoprotection Provided by Additional Diuretic Treatment in Partially Nephrectomized Ren-2 Transgenic Rats Subjected to the Combined RAS and ETA Blockade

Autor: Ivana Vaněčková, Silvie Hojná, Zdenka Vernerová, Michaela Kadlecová, Hana Rauchová, Elzbieta Kompanowska-Jezierska, Zdeňka Vaňourková, Luděk Červenka, Josef Zicha

Publikováno v: Frontiers in Physiology, Vol 10 (2019)

ObjectiveOur previous study in heterozygous Ren-2 transgenic rats (TGR) demonstrated that long-term treatment with endothelin receptor A (ETA) blocker atrasentan added to the renin-angiotensin system (RAS) blockade had renoprotective effects in a mod

Externí odkaz: https://doaj.org/article/8daa08cb54f64a98ac0962f6e60ea410

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Akademický článek

Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats

Autor: Jaroslav Hrdlička, Jan Neckář, František Papoušek, Zuzana Husková, Soňa Kikerlová, Zdenka Vaňourková, Zdenka Vernerová, Firat Akat, Jana Vašinová, Bruce D. Hammock, Sung Hee Hwang, John D. Imig, John R. Falck, Luděk Červenka, František Kolář

Publikováno v: Frontiers in Pharmacology, Vol 10 (2019)

Epoxyeicosatrienoic acids (EETs) and their analogs have been identified as potent antihypertensive compounds with cardio- and renoprotective actions. Here, we examined the effect of EET-A, an orally active EET analog, and c-AUCB, an inhibitor of the

Externí odkaz: https://doaj.org/article/c98a38c7fda04e4a81194d59e2fbbc8c

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Akademický článek

AT1 receptor blocker, but not an ACE inhibitor, prevents kidneys from hypoperfusion during congestive heart failure in normotensive and hypertensive rats

Autor: Vojtech Kratky, Zdenka Vanourkova, Matus Sykora, Barbara Szeiffova Bacova, Zdenka Hruskova, Sona Kikerlova, Zuzana Huskova, Libor Kopkan

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

Abstract To provide novel insights into the pathogenesis of heart failure-induced renal dysfunction, we compared the effects of ACE inhibitor (ACEi) and AT1 receptor blocker (ARB) on systemic and kidney hemodynamics during heart failure in normotensi

Externí odkaz: https://doaj.org/article/268e001c1c7147fca832132a45aab7dd

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AT1 receptor blocker, but not an ACE inhibitor, prevents kidneys from hypoperfusion during congestive heart failure in normotensive and hypertensive rats

Autor: Zdenka Vanourkova, Libor Kopkan, Sona Kikerlova, Barbara Szeiffova Bacova, Vojtech Kratky, Zdenka Hruskova, Matus Sykora, Zuzana Husková

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

To provide novel insights into the pathogenesis of heart failure-induced renal dysfunction, we compared the effects of ACE inhibitor (ACEi) and AT1 receptor blocker (ARB) on systemic and kidney hemodynamics during heart failure in normotensive HanSD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f222798069443c1902571268ae9db904
https://doaj.org/article/268e001c1c7147fca832132a45aab7dd

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Abstract 14613: Preclinical Animal Model of Doxorubicin-induced Left Ventricular Dysfunction: Echocardiography and Pressure-volume Analysis

Autor: Ludek Cervenka, Zdenka Vanourkova, Zuzana Husková, Petra Škaroupková, Petr Kala, Josef Veselka, Vojtech Melenovsky, Zuzana Honetschlägerová

Publikováno v: Circulation. 142

Introduction: There is a need to implement a preclinical model in addition to the well established ischemic or volume-overload models that would mimic the clinical course of patients with chemotherapy-induced heart failure. Doxorubicin is an anthracy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::562af1416f812683e8248537204d0bc4
https://doi.org/10.1161/circ.142.suppl_3.14613

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