Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Zdenka Fronek"'
Autor:
Steven P. Richieri, Joseph A. Markenson, Eric L. Matteson, Joseph M. Cash, Larry W. Moreland, Cornelia M. Weyand, William J. Koopman, Christopher J. Nardo, Leonard H. Calabrese, Joan M. Bathon, Elizabeth E Morgan, Dennis J. Carlo, Steven W. Brostoff, K. M. Uramoto, Thomas C. Adamson, Alan K. Matsumoto, Jocelyn P. Diveley, Zdenka Fronek, Louis W. Heck, Vibeke Strand
Publikováno v:
Arthritis & Rheumatism. 41:1919-1929
OBJECTIVE Restricted T cell receptor (TCR) gene usage has been demonstrated in animal models of autoimmune disease and has resulted in the successful use of TCR peptide therapy in animal studies. This clinical trial was undertaken to determine the sa
Publikováno v:
Journal of Investigative Dermatology. 97(5):799-802
HLA class II DQ and DP genes from dermatitis herpetiformis patients were amplified and analyzed using molecular probes and compared to those from celiac disease patients and to an HLA and ethnically matched control group. In dermatitis herpetiformis,
Publikováno v:
Human Immunology. 30:77-84
Most autoimmune disorders are associated with particular alleles of the major histocompatibility complex (MHC) class II genes. However, only a minority of individuals with these alleles develop autoimmunity. The identification of alleles more closely
Autor:
Zdenka Fronek, Fanny M. Ebling, Kenneth C. Kalunian, James S. Louie, Niver Panosian-Sahakian, Bevra H. Hahn, Hugh O. McDevitt
Publikováno v:
Arthritis & Rheumatism. 33:978-984
Serum levels of IdGN2 (an idiotype enriched in nephritogenic antibodies), IdX (an idiotype not enriched in nephritogenic antibodies), IgG, and anti-DNA were measured in 23 Caucasian patients with lupus nephritis, in age- and sex-matched lupus patient
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 87(3)
We report on the production of tumor necrosis factor (TNF)-alpha and TNF-beta by mitogen-activated peripheral blood lymphocytes or enriched monocyte subpopulations from human leukocyte antigen (HLA)-typed healthy subjects. The results indicate that H
Autor:
John A. Todd, Hans Acha-Orbea, John I. Bell, Nelson Chao, Zdenka Fronek, Chaim O. Jacob, Michael McDermott, Animesh A. Sinha, Luika Timmerman, Lawrence Steinman, Hugh O. McDevitt
Publikováno v:
Science. 240:1003-1009
Class II major histocompatibility (MHC) molecules have an immunoregulatory role. These cell-surface glycoproteins present fragments of protein antigens (or peptides) to thymus-derived lymphocytes (T cells). Nucleotide sequence polymorphism in the gen
Publikováno v:
Clinical Immunology and Immunopathology. 41:91-107
The relationship between the antigenic proteins of Sm and RNP is not clear. To further clarify their relationship, we examined sera found monospecific by counterimmunoelectrophoresis (CIEP) for anti-Sm or anti-RNP with the more sensitive techniques o
Autor:
Jonathan G. Seidman, Allan D. Duby, Daniel Lentz, Karen A. Klein, Zdenka Fronek, Peter H. Schur, Nancy Berliner
Publikováno v:
Arthritis & Rheumatism. 29:1023-1025
The genomic DNA polymorphism of the beta chain of the T cell receptor was examined. The restriction fragment length polymorphism distribution was similar in systemic lupus erythematosus patients, their relatives, and normal controls. Our observations
Autor:
Kenneth C. Kalunian, Zdenka Fronek, Chester A. Alper, Luika A. Timmerman, Hugh O. McDevitt, B. Matija Peterlin, Bevra H. Hahn
Publikováno v:
The American Journal of Medicine. 85:42-44
This study focused on clinical subsets within systemic lupus erythematosus (SLE) in order to identify more homogeneous patient groups in which to define disease susceptibility gene(s). Analysis of the major histocompatibility complex gene products an
Publikováno v:
Arthritis & Rheumatism. 31:573-573