Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Zdenka, Vernerová"'
Autor:
Ivana Vaněčková, Silvie Hojná, Zdenka Vernerová, Michaela Kadlecová, Hana Rauchová, Elzbieta Kompanowska-Jezierska, Zdeňka Vaňourková, Luděk Červenka, Josef Zicha
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
ObjectiveOur previous study in heterozygous Ren-2 transgenic rats (TGR) demonstrated that long-term treatment with endothelin receptor A (ETA) blocker atrasentan added to the renin-angiotensin system (RAS) blockade had renoprotective effects in a mod
Externí odkaz:
https://doaj.org/article/8daa08cb54f64a98ac0962f6e60ea410
Autor:
Jaroslav Hrdlička, Jan Neckář, František Papoušek, Zuzana Husková, Soňa Kikerlová, Zdenka Vaňourková, Zdenka Vernerová, Firat Akat, Jana Vašinová, Bruce D. Hammock, Sung Hee Hwang, John D. Imig, John R. Falck, Luděk Červenka, František Kolář
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Epoxyeicosatrienoic acids (EETs) and their analogs have been identified as potent antihypertensive compounds with cardio- and renoprotective actions. Here, we examined the effect of EET-A, an orally active EET analog, and c-AUCB, an inhibitor of the
Externí odkaz:
https://doaj.org/article/c98a38c7fda04e4a81194d59e2fbbc8c
Autor:
Zdeňka Vaňourková, Zdenka Vernerová, E Koblihová, J. Froněk, M Ryska, H. Maxová, S. Kikerlová, Iveta Mrázová, Zuzana Husková
Publikováno v:
Physiol Res
Acute liver failure (ALF) is known for extremely high mortality rate, the result of widespread damage of hepatocytes. Orthotopic liver transplantation is the only effective therapy but its application is limited by the scarcity of donor organs. Given
Autor:
Ivana Vaněčková, Michaela Kadlecová, J. Zicha, Ludek Cervenka, Libor Kopkan, Zdenka Vernerová, S Hojná
Publikováno v:
Physiological Research. :S55-S67
Chronic kidney disease (CKD) is a life-threatening disease arising as a frequent complication of diabetes, obesity and hypertension. Since it is typically undetected for long periods, it often progresses to end-stage renal disease. CKD is characteriz
Autor:
Hana Rauchová, Luděk Červenka, S Hojná, Zdeňka Vaňourková, Ivana Vaněčková, Michaela Kadlecová, Elzbieta Kompanowska-Jezierska, Josef Zicha, Zdenka Vernerová
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 10 (2019)
Frontiers in Physiology, Vol 10 (2019)
Objective: Our previous study in heterozygous Ren-2 transgenic rats (TGR) demonstrated that long-term treatment with endothelin receptor A (ETA) blocker atrasentan added to the renin-angiotensin system (RAS) blockade had renoprotective effects in a m
Autor:
Ivan Damjanov, Kvetoslava Peckova, Zdenka Vernerová, Michael Michal, Ladislav Hadravsky, Michal Michal, Marketa Miesbauerova, Dmitry V. Kazakov, Saul Suster
Publikováno v:
Histopathology. 69:762-774
Aims Littoral cell angioma (LCA) is a rare primary splenic tumour that is frequently associated with internal malignancies. Immunohistochemistry can demonstrate a distinct hybrid endothelial–histiocytic phenotype of littoral cells, and is a helpful
Autor:
Klára Prajzlerová, Karel Pavelka, Jiří Vencovský, Ladislav Šenolt, Hana Hulejová, David Veigl, Zdenka Vernerová, Mária Filková
Publikováno v:
Cytokine. 73:36-43
Objective Interleukin-35 (IL-35) is a heterodimeric member of the IL-12 family consisting of p35/IL-12a and EBI3/IL-27b subunits. Expressed in murine Treg cells, IL-35 controls inflammatory diseases in mouse models. However, human IL-35 is expressed
Autor:
Denisa Kovářová, Kateřina Trejbalová, Dana Kučerová, Martina Benešová, Tomáš Hron, Jiří Hejnar, Zdenka Vernerová
Publikováno v:
Retrovirology
Background Syncytin-1 and 2, human fusogenic glycoproteins encoded by the env genes of the endogenous retroviral loci ERVWE1 and ERVFRDE1, respectively, contribute to the differentiation of multinucleated syncytiotrophoblast in chorionic villi. In no
Autor:
Šárka Jíchová, Janusz Sadowski, Zuzana Husková, Elzbieta Kompanowska-Jezierska, Libor Kopkan, John R. Falck, Herbert J. Kramer, Zdenka Vernerová, Petr Kujal, Luděk Červenka, Rami N. Reddy, Šárka Doleželová, Jan Neckář, John D. Imig
OBJECTIVE We evaluated the therapeutic effectiveness of a new, orally active epoxyeicosatrienoic acid analog (EET-A) in rats with angiotensin II (ANG II)-dependent malignant hypertension. METHODS Malignant hypertension was induced in Cyp1a1-Ren-2 tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a487f59fa61866faafe4bb44546130f
https://europepmc.org/articles/PMC5510029/
https://europepmc.org/articles/PMC5510029/
Autor:
Hsing Ju Tsai, Zuzana Honetschlägerová, John D. Imig, Alžběta Vojtíšková, Alexandra Sporková, Zuzana Husková, Bruce D. Hammock, Šárka Varcabová, Libor Kopkan, Petr Kujal, Herbert J. Kramer, Zdenka Vernerová, Sung Hee Hwang, Marcela Bürgelová, Luděk Červenka
Publikováno v:
Kidney and Blood Pressure Research. 35:595-607
Objective: The present study was performed to examine whether the blood pressure (BP)-lowering effects of soluble epoxide hydrolase (sEH) inhibition in two-kidney, one-clip (2K1C) Goldblatt hypertension are nitric oxide (NO) dependent. Methods: Mice