Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Zdenek Vavrin"'
Publikováno v:
Redox Biology, Vol 8, Iss C, Pp 271-284 (2016)
Complex metabolism is thought to occur exclusively in the crowded intracellular environment. Here we report that diluted enzymes from lysed human leukocytes produce extracellular energy. Our findings involve two pathways: the purine nucleotide catabo
Externí odkaz:
https://doaj.org/article/b1b2ba89f4c64a1b807f12a4c654e7bc
Publikováno v:
Redox Biology, Vol 8, Iss C, Pp 271-284 (2016)
Redox Biology
Redox Biology
Complex metabolism is thought to occur exclusively in the crowded intracellular environment. Here we report that diluted enzymes from lysed human leukocytes produce extracellular energy. Our findings involve two pathways: the purine nucleotide catabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97019a8ae08f6f9f4bdbae6ef7dbff9
http://www.sciencedirect.com/science/article/pii/S221323171630012X
http://www.sciencedirect.com/science/article/pii/S221323171630012X
Publikováno v:
Scopus-Elsevier
McCoy cells, murine-derived cells commonly used for propagation of chlamydiae, were found to be efficient producers of nitric oxide (NO) when primed with murine gamma interferon (IFN-gamma) and then exposed to the second signals provided by Escherich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb744d25325c1710bcd151bac2f8207
https://doi.org/10.1128/iai.61.2.491-497.1993
https://doi.org/10.1128/iai.61.2.491-497.1993
The murine model of Lyme disease was used to determine the role of inflammatory induced nitric oxide (NO) during infection by the spirochete Borrelia burgdorferi. The outer surface lipoproteins of B. burgdorferi are potent stimulators of inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91445d337e0893ea9c732dafd63f00b6
https://europepmc.org/articles/PMC173547/
https://europepmc.org/articles/PMC173547/
Autor:
C. Kablitz, R. L. Menlove, Read R. Taintor, M. P. McMurry, R. L. Baranowski, Zdenek Vavrin, James P. Kushner, John B. Hibbs, John H. Ward, Christof Westenfelder
An interferon-gamma, tumor necrosis factor, and interleukin-1-inducible, high-output pathway synthesizing nitric oxide (NO) from L-arginine was recently identified in rodents. High-dose interleukin-2 (IL-2) therapy is known to induce the same cytokin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecdb15f8586f42386c5e6ecc3421ec52
https://europepmc.org/articles/PMC442932/
https://europepmc.org/articles/PMC442932/
Autor:
Charles J. Parker, Read R. Taintor, Ina J. Amber, Zdenek Vavrin, Barbara B. Johnson, John B. Hibbs
Publikováno v:
Journal of leukocyte biology. 49(6)
Conditioned medium (CM) from cultures of cytotoxic activated macrophages causes inhibition of mitochondrial respiration, DNA synthesis, and aconitase activity in murine EMT-6 mammary adenocarcinoma cells by an l-arginine dependent effector mechanism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4d194fb2c712ba8a59a77d8e0902fa
https://pubmed.ncbi.nlm.nih.gov/1902865
https://pubmed.ncbi.nlm.nih.gov/1902865
Publikováno v:
Science. 235:473-476
Previous studies have shown that cytotoxic activated macrophages cause inhibition of DNA synthesis, of mitochondrial respiration, and of aconitase activity in tumor target cells. An L-arginine-dependent biochemical pathway synthesizing L-citrulline a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c2cfdc19aa7dc4868d15657746a6e1
https://doi.org/10.1126/science.2432665
https://doi.org/10.1126/science.2432665
SHORT COMMUNICATION: Cytokines Induce an L-Arginine-Dependent Effector System in Nonmacrophage Cells
Publikováno v:
Journal of Leukocyte Biology. 44:58-65
Treatment of EMT-6 mammary adenocarcinoma cells with gamma interferon (rMuIFNγ) plus tumor necrosis factor (rMuTNFα) and/or interleukin-1 (rHuIL-1α) causes release of iron-55 label, inhibition of DNA replication, and inhibition of aconitase activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da7090bb4be332830147e68b46bb5cee
https://doi.org/10.1002/jlb.44.1.58
https://doi.org/10.1002/jlb.44.1.58
Publikováno v:
Journal of Clinical Investigation. 73:806-815
Fibrin deposition is prominent in the histopathology of a number of inflammatory lung diseases. Plasmin, activated locally in the lung, can degrade not only this fibrin but potentially structural proteins important to normal lung architecture. Becaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0053612cd3a1217d9259e42cf4cc711f
https://doi.org/10.1172/jci111275
https://doi.org/10.1172/jci111275
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 76(8)
A high molecular weight fraction of human serum (Fr-1) was found to both inhibit macrophage tumoricidal activity and enhance plasminogen activator activity in supernates over activated macrophages in vitro. Conversely, a 40- to 90-kilodalton serine e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a16639107dbef626eebed0d978f22f
https://pubmed.ncbi.nlm.nih.gov/291048
https://pubmed.ncbi.nlm.nih.gov/291048