Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Zdenek Knejzlik"'
Autor:
Ondřej Bulvas, Zdeněk Knejzlík, Jakub Sýs, Anatolij Filimoněnko, Monika Čížková, Kamila Clarová, Dominik Rejman, Tomáš Kouba, Iva Pichová
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Allosteric regulation of inosine 5′-monophosphate dehydrogenase (IMPDH), an essential enzyme of purine metabolism, contributes to the homeostasis of adenine and guanine nucleotides. However, the precise molecular mechanism of IMPDH regulat
Externí odkaz:
https://doaj.org/article/8cabb055440b47878510600bec877241
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Since the outbreak of the COVID-19 pandemic, the use of hand sanitisers has become an inseparable part of our personal hygiene. However, the short-term effect and the need for frequent application are shortcomings that impair the overall pro
Externí odkaz:
https://doaj.org/article/ab6cc374d15846d08f21d2744ee83c68
Autor:
Petra Janská, Zdeněk Knejzlík, Ayyappasamy Sudalaiyadum Perumal, Radek Jurok, Viola Tokárová, Dan V Nicolau, František Štěpánek, Ondřej Kašpar
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248878 (2021)
Garlic is a well-known example of natural self-defence system consisting of an inactive substrate (alliin) and enzyme (alliinase) which, when combined, produce highly antimicrobial allicin. Increase of alliinase stability and its activity are of para
Externí odkaz:
https://doaj.org/article/0f2acf82111147a4bf0935c5454028b6
Autor:
Helena Gbelcová, Silvie Rimpelová, Zdeněk Knejzlík, Jana Šáchová, Michal Kolář, Hynek Strnad, Vanda Repiská, Walter Cosimo D’Acunto, Tomáš Ruml, Libor Vítek
Publikováno v:
Lipids in Health and Disease, Vol 16, Iss 1, Pp 1-10 (2017)
Abstract Background Statin treatment of hypercholesterolemia is accompanied also with depletion of the mevalonate intermediates, including farnesyl pyrophosphate (FPP) and geranylgeranyl pyrophosphate (GGPP) necessary for proper function of small GTP
Externí odkaz:
https://doaj.org/article/1564237be422436784cf65eb07216dd9
Autor:
Hana Raschmanová, Iwo Zamora, Martina Borčinová, Patrick Meier, Astrid Weninger, Dominik Mächler, Anton Glieder, Karel Melzoch, Zdeněk Knejzlík, Karin Kovar
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Pichia pastoris (Komagataella sp.) is broadly used for the production of secreted recombinant proteins. Due to the high rate of protein production, incorrectly folded proteins may accumulate in the endoplasmic reticulum (ER). To restore their proper
Externí odkaz:
https://doaj.org/article/289591b63495445b82e537f21870a2e8
Autor:
Ivan Novotný, Anna Malinová, Eva Stejskalová, Daniel Matějů, Klára Klimešová, Adriana Roithová, Martin Švéda, Zdeněk Knejzlík, David Staněk
Publikováno v:
Cell Reports, Vol 10, Iss 3, Pp 429-440 (2015)
Cajal bodies (CBs) are evolutionarily conserved nuclear structures involved in the metabolism of spliceosomal small nuclear ribonucleoprotein particles (snRNPs). CBs are not present in all cell types, and the trigger for their formation is not yet kn
Externí odkaz:
https://doaj.org/article/8a427034b60d492fbe660c3428715c63
Publikováno v:
BioTechniques, Vol 53, Iss 3, Pp 1-4 (2012)
Small ubiquitin-related modifier-2/3 (SUMO-2/3) is a member of the ubiquitin-like (Ubl) protein family. Conjugation of SUMO-2/3 to target proteins is influenced by various stress conditions and chemical inhibitors. SUMO-2/3 conjugation may serve as a
Externí odkaz:
https://doaj.org/article/443473a8192d4e2bad85839857467c21
Autor:
Tomáš Ruml, Tjokorda Sari Nindhia, Zdenek Knejzlik, Tjokorda Gde Tirta Nindhia, Akmal Raka Pamungkas, I Wayan Surata
Publikováno v:
Materials Science Forum. 1013:69-74
The cocoon of Antheraea pernyi was grown in the laboratory with tropical artificial conditioning. The caterpillar was fed with Lantana camara leaf. They are 3 protocols provided to yield single fiber from the cocoon. The first protocol developed in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7186f7a52b6deb174c226891887a418
https://doi.org/10.4028/www.scientific.net/msf.1013.69
https://doi.org/10.4028/www.scientific.net/msf.1013.69
Autor:
David Sykora, Nikol Volfova, Silvie Rimpelová, Edita Krizova, Kamila Vapenkova, Vojtech Skop, Zdenek Knejzlik, Diana Rayova, Ivana Krizova, Vaclav Zidek, Sarka Sestakova, Petr Svoboda, Jarmila Zídková, Martin Haluzik, Michaela Rumlová, René Kizek
Publikováno v:
J Biol Chem
Nicotinamide phosphoribosyltransferase (NAMPT) is located in both the nucleus and cytoplasm and has multiple biological functions including catalyzing the rate-limiting step in NAD synthesis. Moreover, up-regulated NAMPT expression has been observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f31538cb5b87f61108c3a5f9f75650
https://doi.org/10.1074/jbc.ra118.003505
https://doi.org/10.1074/jbc.ra118.003505
Autor:
Tomas Ruml lik, Tjokorda Gde Tirta Nindhia, Zdenek Knejzlik, I Wayan Surata, Tjokorda Sari Nindhia
Publikováno v:
International Journal of Pharma Medicine and Biological Sciences. 6:32-36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e0ba9667efc5015896c438237fa3d97
https://doi.org/10.18178/ijpmbs.6.2.32-36
https://doi.org/10.18178/ijpmbs.6.2.32-36