Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Zdena Sulová"'
Autor:
Livia Pelegrinova, Lucia Sofrankova, Jana Spaldova, Pavol Stefik, Zdena Sulova, Albert Breier, Katarina Elefantova
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3107 (2024)
Intracellular calcium, as a second messenger, is involved in multilevel cellular regulatory pathways and plays a role (among other processes) in switching between survival and initiation of cell death in neoplastic cells. The development of multidrug
Externí odkaz:
https://doaj.org/article/d4e21b8316d4490e9aa98e439f9ba1a3
Autor:
Tomáš Kyca, Lucia Pavlíková, Viera Boháčová, Anton Mišák, Alexandra Poturnayová, Albert Breier, Zdena Sulová, Mário Šereš
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5504 (2021)
In this paper, we compared the effects of bortezomib on L1210 (S) cells with its effects on P-glycoprotein (P-gp)-positive variant S cells, which expressed P-gp either after selection with vincristine (R cells) or after transfection with a human gene
Externí odkaz:
https://doaj.org/article/c445c4c27118474193ad600419e8471e
Autor:
Ľuboš Janotka, Lucia Messingerová, Kristína Šimoničová, Helena Kavcová, Katarína Elefantová, Zdena Sulová, Albert Breier
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 2076 (2021)
We established the following two variants of the MOLM-13 human acute myeloid leukemia (AML) cell line: (i) MOLM-13/DAC cells are resistant to 5-aza-2′-deoxycytidine (DAC), and (ii) MOLM-13/AZA are resistant to 5-azacytidine (AZA). Both cell variant
Externí odkaz:
https://doaj.org/article/bc5514ce1abd40d69782788e13c9e0ad
Autor:
Mário Šereš, Lucia Pavlíková, Viera Boháčová, Tomáš Kyca, Ivana Borovská, Boris Lakatoš, Albert Breier, Zdena Sulová
Publikováno v:
Cells, Vol 9, Iss 4, p 890 (2020)
P-glycoprotein (P-gp, ABCB1 member of the ABC (ATP-binding cassette) transporter family) localized in leukemia cell plasma membranes is known to reduce cell sensitivity to a large but well-defined group of chemicals known as P-gp substrates. However,
Externí odkaz:
https://doaj.org/article/eae0748f7c5c4080942a51aad929ed7e
Publikováno v:
Molecules, Vol 23, Iss 2, p 337 (2018)
Multidrug resistance (MDR) is a phenotype of cancer cells with reduced sensitivity to a wide range of unrelated drugs. P-glycoprotein (P-gp)—a drug efflux pump (ABCB1 member of the ABC transporter gene family)—is frequently observed to be a molec
Externí odkaz:
https://doaj.org/article/de65f32784d1411784fc7aff84287e18
Autor:
Kristína Šimoničová, Ľuboš Janotka, Helena Kavcová, Zdena Sulová, Albert Breier, Lucia Messingerova
Publikováno v:
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy. 61
Resistance to the hypomethylating agents (HMAs) 5-azacytidine (AZA) and 5-aza-2'-deoxycytidine (DAC) represents a major obstacle in the treatment of elderly patients with myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) which are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d3d4f50c0c6c12d27c2947e0a1831a
https://pubmed.ncbi.nlm.nih.gov/35227933
https://pubmed.ncbi.nlm.nih.gov/35227933
Publikováno v:
Cancers. 14:1090
Cancer chemotherapy may induce a multidrug resistance (MDR) phenotype. The development of MDR is based on various molecular causes, of which the following are very common: induction of ABC transporter expression; induction/activation of drug-metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738293933c1e94f3208c55e12165f88e
https://doi.org/10.3390/cancers14041090
https://doi.org/10.3390/cancers14041090
Autor:
Lukáš Hubčík, Dominika Galliková, Petra Pullmannová, Ľubica Lacinová, Zdena Sulová, Mária Hanulová, Sergio S. Funari, Ferdinand Devínsky, Daniela Uhríková
Publikováno v:
General physiology and biophysics 37(1), 57-69 (2018). doi:10.4149/gpb_2017042
General physiology and biophysics 37(1), 57 - 69 (2018). doi:10.4149/gpb_2017042
DNA condensation, structure and transfection efficiency of complexes formed by gemini surfactants alkane-α,ω-diyl-bis(dodecyldimethylammonium bromide)s (CnGS12, n
DNA condensation, structure and transfection efficiency of complexes formed by gemini surfactants alkane-α,ω-diyl-bis(dodecyldimethylammonium bromide)s (CnGS12, n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb636ad56509ce00d17cd9692f21cfd8
https://doi.org/10.4149/gpb_2017042
https://doi.org/10.4149/gpb_2017042
Autor:
Katarina, Turáková, Lucia, Pavlíková, Lucia, Messingerová, Boris, Lakatoš, Albert, Breier, Zdena, Sulová
Publikováno v:
Anticancer research. 35(5)
P-glycoprotein (Pgp) expression in neoplastic cells is known to reduce cell sensitivity to several cytotoxic Pgp substrates. A member of the ABC transporter family, Pgp, represents the most frequently described membrane efflux pump and its expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::462cf4c917e104e066cb1d1e211d189a
https://pubmed.ncbi.nlm.nih.gov/25964538
https://pubmed.ncbi.nlm.nih.gov/25964538
Autor:
Lucia, Messingerová, Anna, Jonášová, Miroslav, Barančik, Lenka, Poleková, Mário, Šereš, Lenka, Gibalová, Albert, Breier, Zdena, Sulová
Publikováno v:
General physiology and biophysics. 34(4)
A specific type of myelodysplastic syndrome (MDS) is associated with isolated deletion on the long arm of chromosome 5, i.e., 5q-syndrome (del(5q)). The treatment approaches for MDS del(5q) include the immunomodulating drug lenalidomide (LEN). Thirte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa12af3b1d2ab1da2b761d20bfe01eb3
https://pubmed.ncbi.nlm.nih.gov/26001289
https://pubmed.ncbi.nlm.nih.gov/26001289