Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Zdena Bartosova"'
Publikováno v:
Neoplasma. 56:101-107
UNLABELLED The human multidrug resistance gene (MDR1) is encoding the transmembrane transporter P-glycoprotein (P-gp) which plays an important role in the efflux of various drugs and thus is potentially influencing the drug-treatment outcome. It has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f88b8884901d05599f9e26ef35b754c
https://doi.org/10.4149/neo_2009_02_101
https://doi.org/10.4149/neo_2009_02_101
Autor:
Ada Kolman, Miroslav Chovanec, Eva Markova, Zdena Bartosova, Danuša Vlasáková, Andrej Dudáš, J. Brozmanová
Publikováno v:
Yeast. 20:389-396
The Saccharomyces cerevisiae rad52 mutants are sensitive to many DNA damaging agents, mainly to those that induce DNA double-strand breaks (DSBs). In the yeast, DSBs are repaired primarily by homologous recombination (HR). Since almost all HR events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64a8fe9fd08b42dc651b4ea745c88df5
https://doi.org/10.1002/yea.971
https://doi.org/10.1002/yea.971
Autor:
Pierre Hutter, Karl Heinimann, Hynek Bachraty, Ian Tomlinson, Denisa Ilencikova, Zdena Bartosova, Katarína Bachratá, Salvatore Piscuoglio, Benno Roethlisberger, Michal Kovac, Monika Kovacova
Publikováno v:
Human mutation. 36(2)
Although most of the pertinent data on the sequence-directed processes leading to genome rearrangements (GRs) have come from studies on somatic tissues, little is known about GRs in the germ line of patients with hereditary disorders. This study aims
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2e559c1b0d6ca52524f537bbd50d0a
https://pubmed.ncbi.nlm.nih.gov/25418510
https://pubmed.ncbi.nlm.nih.gov/25418510
Autor:
Iveta Mlkva, Miriam Vizvaryova, Michal Konecny, Vladimíra Vranová, Juraj Kausitz, Zdena Bartosova, Petr Kuglík, Eva Weismanova, Katarina Zavodna
Publikováno v:
Breast Cancer Research and Treatment. 109:581-583
The Large genomic rearrangements (LGR) in BRCA1/2 represent a substantial proportion of disease-causing changes. In our pilot study we demonstrate the specific case of the Slovak breast/ovarian cancer family, where BRCA1 analysis revealed the discrep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79800fc518494ebbfe98c987fa10690
https://doi.org/10.1007/s10549-007-9670-0
https://doi.org/10.1007/s10549-007-9670-0
Autor:
Zdena Bartosova, Juraj Kausitz, Miriam Milly, Iveta Mlkva, Eva Weismanova, Jaroslava Gregorova, Katarina Zavodna, Denisa Ilencikova, Michal Konecny
Publikováno v:
Breast cancer research and treatment. 126(1)
Germline mutations in the BRCA1/2 genes account for the majority of hereditary breast ovarian cancer (HBOC). Identification of causal mutations may have significant impact on clinical management of such families. Despite high mutation detection rate,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f08e7598676b4f9d9c57355a96867a77
https://pubmed.ncbi.nlm.nih.gov/21203900
https://pubmed.ncbi.nlm.nih.gov/21203900
Autor:
Tomas Slamka, Zdena Bartosova, Bujalkova M, Tomas Krivulcik, David Martinicky, Denisa Ilencikova, Katarina Zavodna
Publikováno v:
BMC Cancer, Vol 9, Iss 1, p 405 (2009)
BMC Cancer
BMC Cancer
Background Depending on the population studied, large genomic rearrangements (LGRs) of the mismatch repair (MMR) genes constitute various proportions of the germline mutations that predispose to hereditary non-polyposis colorectal cancer (HNPCC). It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2afc68d21bf2c5543c5db12149655318
https://doi.org/10.1186/1471-2407-9-405
https://doi.org/10.1186/1471-2407-9-405
Autor:
Giancarlo Marra, Josef Jiricny, Denisa Ilencikova, Tomas Krivulcik, Bujalkova M, Brigitte Wolf, Karl Heinimann, Katarina Zavodna, Zdena Bartosova, Michal Kovac, Judith Karner-Hanusch
Publikováno v:
Clinical chemistry. 54(11)
Background: In the workup of patients with suspected hereditary nonpolyposis colorectal cancer (HNPCC), detection of loss of heterozygosity (LOH) could help pinpoint the mismatch-repair (MMR) gene carrying the germline mutation, but analysis of micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::510f107bbe4cd97a30686e41edb50808
https://pubmed.ncbi.nlm.nih.gov/18772310
https://pubmed.ncbi.nlm.nih.gov/18772310
Autor:
Ivan Chalupa, Zdena Bartosova, Katarína Horáková, Lubomir Floch, Jana Jakubikova, Juraj Bodo, Jan Sedlak
Publikováno v:
Apoptosis : an international journal on programmed cell death. 11(8)
The effect of synthetic isothiocyanate ethyl-4-isothiocyanatobutanoate (E-4IB) on survival of mismatch repair-proficient TK6 and -deficient MT1 cell lines as well as the influence of proteasomal inhibitor MG132, caspase inhibitor Z-VAD-fmk, and ATM i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18179f9a555ea1e2c8246e2e1c9f4e21
https://pubmed.ncbi.nlm.nih.gov/16830228
https://pubmed.ncbi.nlm.nih.gov/16830228
Autor:
László, Czakó, László, Tiszlavicz, Róbert, Takács, Gellért, Baradnay, János, Lonovics, Gábor, Cserni, Katarina, Závodná, Zdena, Bartosova
Publikováno v:
Orvosi hetilap. 146(20)
Hereditary nonpolyposis colorectal cancer is an inherited disease characterized by onset at an early age, an excess of synchronous and metachronous large bowel tumors and a variety of extracolorectal malignancies. Basal and squamous cell carcinomas o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::481a473b084c9829d23cce47bc220636
https://pubmed.ncbi.nlm.nih.gov/15945244
https://pubmed.ncbi.nlm.nih.gov/15945244
Autor:
Zdena, Bartosova, Ivana, Fridrichova, Maria, Bujalkova, Brigitte, Wolf, Denisa, Ilencikova, Peter, Krizan, Peter, Hlavcak, Julius, Palaj, Ludovit, Lukac, Margita, Lukacova, Andrej, Böör, Ritva, Haider, Josef, Jiricny, Minna, Nyström-Lahti, Giancarlo, Marra
Publikováno v:
Human mutation. 21(4)
Hereditary nonpolyposis colorectal cancer (HNPCC) is a dominantly-inherited cancer predisposition syndrome, in which the susceptibility to cancer of the colon, endometrium and ovary is linked to germline mutations in DNA mismatch repair (MMR) genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8caccf845eb991e1430f685a219e34e
https://pubmed.ncbi.nlm.nih.gov/12655568
https://pubmed.ncbi.nlm.nih.gov/12655568