Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Zdeněk Hel"'
Publikováno v:
International Journal of Infectious Diseases, Vol 146, Iss , Pp 107144- (2024)
Externí odkaz:
https://doaj.org/article/ae0822574c3b4d1e995c2282989cb123
Autor:
Eliška Miková, Viktor Černý, Olga Novotná, Petra Petrásková, Kristýna Boráková, Zdenek Hel, Jiří Hrdý
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe immune systems of both the mother and the newborn face significant challenges during birth. Proper immune regulation after birth is essential for the survival of neonates. Numerous studies have demonstrated that the neonatal immune sy
Externí odkaz:
https://doaj.org/article/4f426c433caf4f06b3a93f6c91a9492e
Publikováno v:
International Journal of Immunopathology and Pharmacology
Common variable immunodeficiency disorders (CVIDs) represent a group of primary immunodeficiency diseases characterized by hypogammaglobulinemia and dysfunctional immune response to invading pathogens. Previous studies have indicated that CVID is ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17b89e7930e24c30925a2f829981532
https://doi.org/10.1177/2058738419843381
https://doi.org/10.1177/2058738419843381
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 526 (2024)
IFN-λ is a type III interferon (IFN) with pleiotropic functions in modulating immune responses. To address its function in autoimmune neuroinflammation, we evaluated the development and progression of experimental autoimmune encephalitis (EAE) in IF
Externí odkaz:
https://doaj.org/article/147fc30b1d9b43fd8a5e43122ec694b3
Autor:
Jim Tartaglia, Genoveffa Franchini, Nicolas Rose, Marcin Moniuszko, Lindsey Hocker, Janos Nacsa, Vaniambadi S. Kalyanaraman, Igor M. Belyakov, Sampa Santra, Yvette Edghill-Smith, Norman L. Letvin, Lauren Hudacik, Ranajit Pal, David C. Montefiori, Zdeněk Hel, David Venzon, Jay A. Berzofsky, Phillip D. Markham, Robyn Washington Parks
Publikováno v:
Journal of Virology. 80:3732-3742
Due to the alarming spread of human immunodeficiency virus type 1 (HIV-1) infection worldwide, the development of a prophylactic vaccine is critical. Vaccine strategies for AIDS have included the use of structural and nonstructural HIV subunit protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f281b4584c8071b0212cb23d3ba4d6f
https://doi.org/10.1128/jvi.80.8.3732-3742.2006
https://doi.org/10.1128/jvi.80.8.3732-3742.2006
Autor:
Elzbieta Tryniszewska, Janos Nacsa, Genoveffa Franchini, Zdeněk Hel, Jim Tartaglia, George N. Pavlakis, Phillip D. Markham, Barbara K. Felber, Mark G. Lewis, Wen-Po Tsai
Publikováno v:
The Journal of Immunology. 176:85-96
An HIV-1 vaccine able to induce broad CD4+ and CD8+ T cell responses may provide long-term control of viral replication. In this study we directly assess the relative benefit of immunization with vaccines expressing three structural Ags (Gag, Pol, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d504268ff5673a40b9251f34bf3ffcc
https://doi.org/10.4049/jimmunol.176.1.85
https://doi.org/10.4049/jimmunol.176.1.85
Autor:
Ashley N. Connelly, Richard P. H. Huijbregts, Harish C. Pal, Valeriya Kuznetsova, Marcus D. Davis, Krystle L. Ong, Christian X. Fay, Morgan E. Greene, Edgar T. Overton, Zdenek Hel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Neutrophils are the most abundant circulating leukocyte population with critical roles in immune defense, regulation of innate and adaptive immune systems, and disease pathogenesis. Our progress in understanding precise mechanisms of neutrop
Externí odkaz:
https://doaj.org/article/6b8d06a67b1c44c3b330ffebdad63b65
Autor:
Zdeněk Hel, David Venzon, Genoveffa Franchini, Elzbieta Tryniszewska, Robyn Washington Parks, Mark G. Lewis, Jim Tartaglia, David C. Montefiori, Marcin Moniuszko, Kendall A. Smith, Peter Silvera, Janos Nacsa
Publikováno v:
Scopus-Elsevier
A cohort of rhesus macaques with long-standing SIVmac251 infection (≥5 mo) was treated with continuous antiretroviral therapy (ART). A group of eight macaques was vaccinated with or without simultaneous administration of low dose IL-2 with the high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a2bb83ab90d38ec1f7fd2b0483afbb
https://doi.org/10.4049/jimmunol.169.9.5347
https://doi.org/10.4049/jimmunol.169.9.5347
Autor:
Tatiana S. Karpova, Genoveffa Franchini, Julie M. Johnson, John D. Altman, James G. McNally, Jim Tartaglia, V.S. Kalyanaraman, Zdeněk Hel, Robert Harrod, Wen-Po Tsai, Elzbieta Tryniszewska, Jake Fullen, Barbara K. Felber
Publikováno v:
DNA and Cell Biology. 21:619-626
Most vaccine modalities for human immunodeficiency virus type 1 (HIV-1) tested for immunogenicity and efficacy in the SIVmac (simian immunodeficiency virus) macaque model do not include the viral regulatory proteins. Because viral regulatory proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a8ecbbb5b84a9a91888cd491b7b39d
https://doi.org/10.1089/104454902760330156
https://doi.org/10.1089/104454902760330156
Autor:
Zdeněk Hel, Janos Nacsa, Elzbieta Tryniszewska, Liljana Stevceva, Brian L. Kelsall, Marcin Moniuszko, Genoveffa Franchini
Publikováno v:
Journal of Virology. 76:9-18
Most human immunodeficiency virus (HIV) type 1 infections occur by the mucosal route. Thus, it is important to assess the immune responses to HIV in the vaginal, cervical, and rectal compartments. Here we quantitated the virus-specific CD8+T-cell res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed996213f7f60b1162b5818368ad99cf
https://doi.org/10.1128/jvi.76.1.9-18.2002
https://doi.org/10.1128/jvi.76.1.9-18.2002