Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Zdeněk, Paris"'
Publikováno v:
RNA Biology, Vol 19, Iss 1, Pp 650-661 (2022)
The nuclear pore complex (NPC) facilitates the trafficking of proteins and RNA between the nucleus and cytoplasm. The role of nucleoporins (Nups) in transport in the context of the NPC is well established, yet their function in tRNA export has not be
Externí odkaz:
https://doaj.org/article/05d4eea07e91443ebbed12311667a159
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 5, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/afe2f117778545399d181e3b553d0b6a
Autor:
Ambar Kachale, Zuzana Pavlíková, Anna Nenarokova, Adriana Roithová, Ignacio M. Durante, Petra Miletínová, Kristína Záhonová, Serafim Nenarokov, Jan Votýpka, Eva Horáková, Robert L. Ross, Vyacheslav Yurchenko, Petra Beznosková, Zdeněk Paris, Leoš Shivaya Valášek, Julius Lukeš
Publikováno v:
Nature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b01dc8b1005d992ec1efdd9635e2d9b9
https://doi.org/10.1038/s41586-023-06260-9
https://doi.org/10.1038/s41586-023-06260-9
Autor:
Sameer Dixit, Alan C Kessler, Jeremy Henderson, Xiaobei Pan, Ruoxia Zhao, Gabriel Silveira D’Almeida, Sneha Kulkarni, Mary Anne T Rubio, Eva Hegedűsová, Robert L Ross, Patrick A Limbach, Brian D Green, Zdeněk Paris, Juan D Alfonzo
Publikováno v:
Nucleic Acids Research
Dixit, S, Kessler, A C, Henderson, J, Pan, X, Zhao, R, D'Almeida, G S, Kulkarni, S, Rubio, M A T, Hegedűsová, E, Ross, R L, Limbach, P A, Green, B D, Paris, Z & Alfonzo, J D 2021, ' Dynamic queuosine changes in tRNA couple nutrient levels to codon choice in Trypanosoma brucei ', Nucleic Acids Research, vol. 49, no. 22, pp. 12986-12999 . https://doi.org/10.1093/nar/gkab1204
Dixit, S, Kessler, A C, Henderson, J, Pan, X, Zhao, R, D'Almeida, G S, Kulkarni, S, Rubio, M A T, Hegedűsová, E, Ross, R L, Limbach, P A, Green, B D, Paris, Z & Alfonzo, J D 2021, ' Dynamic queuosine changes in tRNA couple nutrient levels to codon choice in Trypanosoma brucei ', Nucleic Acids Research, vol. 49, no. 22, pp. 12986-12999 . https://doi.org/10.1093/nar/gkab1204
Every type of nucleic acid in cells undergoes programmed chemical post-transcriptional modification. Generally, modification enzymes use substrates derived from intracellular metabolism, one exception is queuine (q)/queuosine (Q), which eukaryotes ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2ee557655385c375eb4defff11dae6
https://doi.org/10.1093/nar/gkab1204
https://doi.org/10.1093/nar/gkab1204
Autor:
Patrick A. Limbach, Mary Anne T. Rubio, Zdeněk Paris, Eva Hegedűsová, Robert L. Ross, Sneha Kulkarni, Juan D. Alfonzo
Publikováno v:
Nucleic Acids Research
Transfer RNAs (tRNAs) are key players in protein synthesis. To be fully active, tRNAs undergo extensive post-transcriptional modifications, including queuosine (Q), a hypermodified 7-deaza-guanosine present in the anticodon of several tRNAs in bacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598d1692e642c71c03b24bde2844b2f6
https://doi.org/10.1093/nar/gkab567
https://doi.org/10.1093/nar/gkab567
Autor:
Zdeněk Paris, Eva Hegedűsová, Ashutosh P. Dubey, Martin Ciganda, Jan Naseer Kaur, Amartya Mishra, Laurie K. Read, Daniel I. McSkimming
Publikováno v:
Mol Microbiol
Kinetoplastids, including Trypanosoma brucei, control gene expression primarily at the posttranscriptional level. Nuclear mRNA export is an important, but understudied, step in this process. The general heterodimeric export factors, Mex67/Mtr2, funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e60dd3b7ffd68d3deaa0093ba6f910
https://doi.org/10.1111/mmi.14773
https://doi.org/10.1111/mmi.14773
Publikováno v:
Nucleic Acids Research
Transfer RNAs (tRNAs) are central players in protein synthesis, which in Eukarya need to be delivered from the nucleus to the cytoplasm by specific transport receptors, most of which belong to the evolutionarily conserved beta-importin family. Based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe247a29d771384f4951b28522a36be
https://doi.org/10.1093/nar/gkz671
https://doi.org/10.1093/nar/gkz671
Nuclear tRNA export in trypanosomes: a journey full of twists and turns guided by tRNA modifications
Autor:
Zdeněk Paris
Publikováno v:
Parasitology
Transfer RNAs play a key role in protein synthesis. Following transcription, tRNAs are extensively processed prior to their departure from the nucleus to become fully functional during translation. This includes removal of 5′ leaders and 3′ trail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41c3f1a3bf04bd5ed28e93703e62e49
https://pubmed.ncbi.nlm.nih.gov/33729118
https://pubmed.ncbi.nlm.nih.gov/33729118
Autor:
Zdeněk Paris, Juan D. Alfonzo
Publikováno v:
IUBMB Life. 70:1207-1213
Organisms have evolved different strategies to seclude certain molecules to specific locations of the cell. This is most pronounced in eukaryotes with their extensive intracellular membrane systems. Intracellular compartmentalization is particularly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f52ab6f538ea9e483b15bc59a40e57c
https://doi.org/10.1002/iub.1957
https://doi.org/10.1002/iub.1957
Autor:
Mary Anne T. Rubio, Alan C. Kessler, Zdeněk Paris, Mellie June Paulines, Sneha Kulkarni, Juan D. Alfonzo, Patrick A. Limbach
Publikováno v:
RNA Biology. 15:528-536
Retrograde transport of tRNAs from the cytoplasm to the nucleus was first described in Saccharomyces cerevisiae and most recently in mammalian systems. Although the function of retrograde transport...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::529c8e929292d850e8a691bac4391f92
https://doi.org/10.1080/15476286.2017.1377878
https://doi.org/10.1080/15476286.2017.1377878