Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Zdeňka Rottnerová"'
Heterocyclic sterol probes for live monitoring of sterol trafficking and lysosomal storage disorders
Autor:
Jarmila Králová, Michal Jurášek, Lucie Krčová, Bohumil Dolenský, Ivan Novotný, Michal Dušek, Zdeňka Rottnerová, Michal Kahle, Pavel Drašar, Petr Bartůněk, Vladimír Král
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract The monitoring of intracellular cholesterol homeostasis and trafficking is of great importance because their imbalance leads to many pathologies. Reliable tools for cholesterol detection are in demand. This study presents the design and synt
Externí odkaz:
https://doaj.org/article/0647f34dfb5f4375bc68e664338d2298
Autor:
Bahareh Khezri, Jan Plutnar, Martin Pumera, Lukas Dekanovsky, Zdeňka Rottnerová, Filip Novotny
Publikováno v:
Nature Machine Intelligence. 2:711-718
The occurrence of synthetic and natural hormones in an aqueous environment poses significant risks to humans because of their endocrine-disrupting activity. Autonomous self-propelled and remotely actuated nano/microrobots have emerged as a new field
Autor:
Pavel Drašar, Petr Bartůněk, Vladimíra Pavlíčková, Eliška Staňková, Zdeňka Rottnerová, Tomáš Ruml, Michal Jurášek, Kamil Záruba, Marketa Simkova, Jan Fähnrich, Silvie Rimpelová, David Sedlák, Oldřich Lapčík, David Kodr
Publikováno v:
Journal of Materials Chemistry B. 7:5465-5477
Photodynamic therapy has become a feasible direction for the treatment of both malignant and non-malignant diseases. It has been in the spotlight since FDA regulatory approval was granted to several photosensitizers worldwide. Nevertheless, there are
Selectivity of original C-hexopyranosyl calix[4]arene conjugates towards lectins of different origin
Autor:
Jitka Moravcová, Eva Fujdiarová, Martina Hlaváčková, Martina Kašáková, Lenka Malinovská, Hana Dvořáková, Olga Maťátková, Michaela Wimmerová, Pavel Lhoták, Zdeňka Rottnerová, Tomáš Klejch
Publikováno v:
Carbohydrate Research. 469:60-72
As a part of ongoing activities towards the design of ligands against pathogenic lectins, a synthesis of original α-C-galacto/α-C-manno/α-C-fucopyranosyl glycomimetics based on a calix[4]arene scaffold and their binding evaluation is described. Th
Autor:
Karolina Strakova, Zdeňka Rottnerová, Tomáš Neveselý, Radek Cibulka, Eva Svobodová, Michael Jirásek
Publikováno v:
European Journal of Organic Chemistry. 2017:2139-2146
[2+2] Photocycloaddition mediated by 1-butyl-3-methyl-7,8-dimethoxyalloxazine (1) is shown as an effective tool to cyclise ω-phenyl and ω,ω'-diphenyl-4-aza-1,6-heptadienes, with the nitrogen atom protected by acylation or quaternisation, used towa
Autor:
Tereza Jirásková, Markéta Berčíková, Vladimír Filip, Iveta Hrádková, Veronika Brychová, Zdeňka Rottnerová, Tereza Honzíková, Jan Kyselka, Tereza Váchalová, Katsiaryna Alishevich
Publikováno v:
Journal of agricultural and food chemistry. 67(35)
Targeted analysis confirmed the presence of new phytosterol degradation products in fully hydrogenated commercial samples. EI-MS, APCI-MS, and 1D-NMR experiments led to the identification of 10 novel markers of catalytic hydrogenation, among which 5
Autor:
Vojtěch Spiwok, Michal Jurášek, Jiří Bejček, Jan Fähnrich, Vladimíra Pavlíčková, Zdeňka Rottnerová, Kamil Záruba, Silvie Rimpelová, Ivana Křížová, Tomáš Ruml, Pavel Drašar
Publikováno v:
Molecules
Volume 24
Issue 24
Volume 24
Issue 24
Purpurin 18 derivatives with a polyethylene glycol (PEG) linker were synthesized as novel photosensitizers (PSs) with the goal of using them in photodynamic therapy (PDT) for cancer. These compounds, derived from a second-generation PS, exhibit absor
Heterocyclic sterol probes for live monitoring of sterol trafficking and lysosomal storage disorders
Autor:
Petr Bartunek, Bohumil Dolensky, Ivan Novotný, Zdeňka Rottnerová, Michal Dušek, Michal Jurášek, Vladimír Král, Jarmila Kralova, Pavel Drašar, Michal Kahle, Lucie Krčová
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
The monitoring of intracellular cholesterol homeostasis and trafficking is of great importance because their imbalance leads to many pathologies. Reliable tools for cholesterol detection are in demand. This study presents the design and synthesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55df46abdf38bfc35adfe92f0e493733
https://doi.org/10.1101/267948
https://doi.org/10.1101/267948
Autor:
Pavel Drašar, Miloš Buděšínský, Petra Mikšátková, Zdeňka Rottnerová, Lukáš Huml, Juraj Harmatha, Tomáš Zimmermann, Marketa Simkova, Michal Jurášek, Oldřich Lapčík, Pavla Tomanová, Eva Kmoníčková
Publikováno v:
Steroids. 117
Trilobolide (Tb) is a pharmacologically interesting sesquiterpene lactone isolated from Laser trilobum (L.) Borkh. Structural relation to a sarco/endoplasmic reticulum Ca2+-ATPase inhibitor thapsigargin bring promising prospects for Tb to be used in