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Autor:
Oliver Profant, Milan Jilek, Zbynek Bures, Vaclav Vencovsky, Diana Kucharova, Veronika Svobodova, Jiri Korynta, Josef Syka
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Age related hearing loss (presbycusis) is one of the most common sensory deficits in the aging population. The main subjective ailment in the elderly is the deterioration of speech understanding, especially in a noisy environment, which cannot solely
Externí odkaz:
https://doaj.org/article/8be81df637734763825738c9a4bff052
Publikováno v:
Hearing Research. 409:108306
Previous experiments have acknowledged that inappropriate or missing auditory inputs during the critical period of development cause permanent changes of the structure and function of the auditory system (Bures et al., 2017). We explore in this study
Autor:
Diana Tothova, Zbynek Bures, Jiri Popelar, Tetyana Chumak, Iva Filova, Josef Syka, Gabriela Pavlinkova
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4507, p 4507 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 9
International Journal of Molecular Sciences
Volume 22
Issue 9
The LIM homeodomain transcription factor ISL1 is essential for the different aspects of neuronal development and maintenance. In order to study the role of ISL1 in the auditory system, we generated a transgenic mouse (Tg) expressing Isl1 under the Pa
Autor:
Oliver Profant, Milan Jilek, Zbynek Bures, Vaclav Vencovsky, Diana Kucharova, Veronika Svobodova, Jiri Korynta, Josef Syka
Publikováno v:
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Vol 11 (2019)
Frontiers in Aging Neuroscience, Vol 11 (2019)
Age related hearing loss (presbycusis) is one of the most common sensory deficits in the aging population. The main subjective ailment in the elderly is the deterioration of speech understanding, especially in a noisy environment, which cannot solely
Autor:
Zbynek Bures
Publikováno v:
Biological Cybernetics. 106:111-122
In the nervous system, the representation of signals is based predominantly on the rate and timing of neuronal discharges. In most everyday tasks, the brain has to carry out a variety of mathematical operations on the discharge patterns. Recent findi
Publikováno v:
European Journal of Neuroscience. 32:155-164
During the early postnatal development of rats, the structural and functional maturation of the central auditory nuclei strongly relies on the natural character of the incoming neural activity. Even a temporary deprivation in the critical period resu
Autor:
Josef Syka, Rostislav Turecek, Zbynek Bures, Michaela Kralikova, Johana Trojanova, Kateryna Pysanenko, Laurence O. Trussell, Bohdana Hruskova, Akos Kulik
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(47)
The properties of glycine receptors (GlyRs) depend upon their subunit composition. While the prevalent adult forms of GlyRs are heteromers, previous reports suggested functional α homomeric receptors in mature nervous tissues. Here we show two funct
Autor:
Zbynek Bures
Publikováno v:
Proceedings of Meetings on Acoustics.
In mammals, spatial hearing is supported by evaluation of two types of binaural disparities, interaural time difference (ITD) and interaural level difference (ILD), which is performed by auditory neurons in the superior olivary complex. Using a compl