Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Zbigniew Kmieć"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionHeme oxygenase-1 (HO-1) is a stress-inducible heat shock protein (HSP32) that exerts cytoprotective effects against oxidative stress and inflammation, and is involved in the maintenance of cellular homeostasis. This study aimed to evaluat
Externí odkaz:
https://doaj.org/article/e57cde9cb2ff4cba879acd9bda7d6026
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 3038 (2024)
We investigated the age-related effects of the lipid-lowering drug fenofibrate on renal stress-associated effectors. Young and old rats were fed standard chow with 0.1% or 0.5% fenofibrate. The kidney cortex tissue structure showed typical aging-rela
Externí odkaz:
https://doaj.org/article/07b42b4cd2e343b9942feb2b05947cd9
Publikováno v:
Immunity & Ageing, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background NKT-like cells are T lymphocytes coexpressing several NK cell-associated receptors. They are effector lymphocytes of innate and adaptive immunity, and their number increases with age. The study aimed to analyze the expression of c
Externí odkaz:
https://doaj.org/article/a67713c79e0d403fa1ee8b59747c51a7
Autor:
Mateusz Czajkowski, Piotr M. Wierzbicki, Anna Kotulak-Chrząszcz, Bartosz Małkiewicz, Roman Sosnowski, Zbigniew Kmieć, Marcin Matuszewski
Publikováno v:
Medicina, Vol 59, Iss 9, p 1623 (2023)
Background and Objectives: Penile cancer is a rare neoplasm in developed countries with an incidence of 0.8/100,000 per male inhabitant. Despite the development of personalized medicine and multimodal treatment, the outcome of penile cancer treatment
Externí odkaz:
https://doaj.org/article/d0293375b6704bdeaf45b1bb76032eb1
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8393 (2023)
Klotho is a beta-glucuronidase that reveals both anti-inflammatory and anti-oxidative properties that have been associated with mechanisms of aging. The study aimed to analyze the relationships between the serum concentration of soluble α-Klotho and
Externí odkaz:
https://doaj.org/article/02abad82a5e4410897f7bd4873da32b3
Publikováno v:
Immunity & Ageing, Vol 15, Iss 1, Pp 1-18 (2018)
Abstract Background NK cells are cytotoxic lymphocytes of innate immunity composed of: cytotoxic CD56dim and immunoregulatory CD56bright cells. The study aimed to analyze the expression of cellular protective proteins: sirtuin 1 (SIRT1), heat shock p
Externí odkaz:
https://doaj.org/article/a7917c16dc2242ffba5ba59531f99f43
Publikováno v:
Central European Journal of Immunology, Vol 43, Iss 3, Pp 306-313 (2018)
Following the discovery of methods to generate large numbers of specific dendritic cells (DCs) ex vivo, the possibility of exploiting these cells in immunotherapeutic strategies will become a reality. It seems to be rationally to analyse the influenc
Externí odkaz:
https://doaj.org/article/e14e66c80b134dfd9ce34c9dbff1023b
Autor:
Lucyna Kaszubowska, Jerzy Foerster, Jan Jacek Kaczor, Daria Schetz, Tomasz Jerzy Ślebioda, Zbigniew Kmieć
Publikováno v:
Immunity & Ageing, Vol 15, Iss 1, Pp 1-16 (2018)
Abstract Background Natural killer cells (NK cells) are cytotoxic lymphocytes of innate immunity that reveal some immunoregulatory properties, however, their role in the process of ageing is not completely understood. The study aimed to analyze the e
Externí odkaz:
https://doaj.org/article/c4a2f3eec2e34fb2a5f80cbabd71a455
Autor:
Magdalena Szaryńska, Agata Olejniczak-Kęder, Adrian Zubrzycki, Anna Wardowska, Zbigniew Kmieć
Publikováno v:
Applied Sciences, Vol 11, Iss 21, p 10009 (2021)
Cancer cells, especially cancer stem cells (CSCs), are known for their therapeutic resistance and ability to induce a cancer relapse even many years after successful treatment. The quest for a novel protocol utilizing some commonly used non-oncologic
Externí odkaz:
https://doaj.org/article/f238bb1d04a6494ca9f44fcad3067636
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10597 (2021)
Acute myeloid leukemia is characterized by uncontrolled clonal proliferation of abnormal myeloid progenitor cells. Despite recent advances in the treatment of this disease, the prognosis and overall long-term survival for patients remain poor, which
Externí odkaz:
https://doaj.org/article/f584b586f3a149b68ccee988a949aadb