Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Zbigniew, Czarnocki"'
Publikováno v:
Applied Sciences, Vol 13, Iss 4, p 2192 (2023)
This study aimed to determine the antioxidant properties of the sulfate monoesters of ferulic, caffeic, dihydroferulic and dihydrocaffeic acids, the main metabolites of chlorogenic acids. These compounds are not commercially available, so they were s
Externí odkaz:
https://doaj.org/article/ea80462b2a294cb0bdc730d22bc41fec
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2384-2393 (2018)
Background: Atropisomers are very interesting stereoisomers having axial chirality resulting from restricted rotation around single bonds and are found in various classes of compounds. ortho-Substituted arylpyridines are an important group of them. A
Externí odkaz:
https://doaj.org/article/402e6e0decdd4c05aeade61bac57d3d3
Autor:
Dariusz Adam Błachut, Joanna Szawkało, Piotr Pomarański, Piotr Roszkowski, Jan K. Maurin, Zbigniew Czarnocki
Publikováno v:
ARKIVOC, Vol 2017, Iss 2, Pp 369-389 (2016)
Externí odkaz:
https://doaj.org/article/97b8910181d24a72aa79939d36470132
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 835-845 (2016)
A series of differently substituted 3,5-diaryl-2,4,6-trimethylpyridines were prepared and characterized using the Suzuki–Miyaura coupling reaction with accordingly selected bromo-derivatives and arylboronic acids. The reaction conditions were caref
Externí odkaz:
https://doaj.org/article/aec1fe007cf14580a08dda09bf86e2d6
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 1509-1513 (2015)
A simple enantioselective synthetic procedure for the preparation of mianserin and epinastine in optically pure form is described. The key step in the synthetic pathway is the asymmetric reduction of the cyclic imine using asymmetric transfer hydroge
Externí odkaz:
https://doaj.org/article/e5eb73ed00134ec6b866c4895865a7c8
Autor:
Piotr F. J. Lipiński, Piotr Kosson, Joanna Matalińska, Piotr Roszkowski, Zbigniew Czarnocki, Małgorzata Jarończyk, Aleksandra Misicka, Jan Cz. Dobrowolski, Joanna Sadlej
Publikováno v:
Molecules, Vol 24, Iss 4, p 740 (2019)
Interactions of 21 fentanyl derivatives with μ-opioid receptor (μOR) were studied using experimental and theoretical methods. Their binding to μOR was assessed with radioligand competitive binding assay. A uniform set of binding affinity data cont
Externí odkaz:
https://doaj.org/article/d0d92795855649f1a53b628ab3091545
Publikováno v:
Arkivoc. 2020:46-55
Autor:
Amanda Suárez Fernández, Adriana González Gago, Francisco Artime Naveda, Javier García Calleja, Anna Zawadzka, Zbigniew Czarnocki, Juan Carlos Mayo Barrallo, Rosa M. Sainz Menéndez, Pablo Rodríguez-González, J. Ignacio García Alonso
Publikováno v:
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
We evaluate here different analytical strategies for the chromatographic separation and determination of N-acetyl-5-methoxytryptamine (MEL) and its oxidative metabolites N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK), N1-acetyl-5-methoxykynuramine (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88ea0bc2e7c15dc0df7a50ab2894600a
http://hdl.handle.net/10651/65090
http://hdl.handle.net/10651/65090
Autor:
Zuzanna Molęda, Anna Zawadzka, Jan K. Maurin, Zbigniew Czarnocki, Armand Budzianowski, Leticia Monjas, Anna K. H. Hirsch
Publikováno v:
Bioorganic and Medicinal Chemistry, 42:116269. PERGAMON-ELSEVIER SCIENCE LTD
Cholinesterase inhibitors are potent therapeutics in the treatment of Alzheimer's disease. Among them, dual binding ligands have recently gained a lot of attention. We discovered novel dual-binding cholinesterase inhibitors, using “clickable” fra
Autor:
Piotr Pomarański, Zbigniew Czarnocki
Publikováno v:
Synthesis. 51:3356-3368
The synthesis of novel l-prolinal dithioacetal and its application as an organocatalyst for the direct Michael addition of cyclic ketones and acetophenone derivatives to trans-β-nitrostyrene and related compounds is described. The prolinal dithioace