Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Zaynab Nouhi"'
Autor:
Katie Fooks, Gabriela Galicia-Vazquez, Victor Gife, Alejandro Schcolnik-Cabrera, Zaynab Nouhi, William W. L. Poon, Vincent Luo, Ryan N. Rys, Raquel Aloyz, Alexandre Orthwein, Nathalie A. Johnson, Laura Hulea, Francois E. Mercier
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Acute myeloid leukemia (AML) is an aggressive hematological cancer resulting from uncontrolled proliferation of differentiation-blocked myeloid cells. Seventy percent of AML patients are currently not cured with available treatmen
Externí odkaz:
https://doaj.org/article/e6bb8583447d4acda27cf156d9e76eb8
Flaviviruses alter endoplasmic reticulum-mitochondria contacts to regulate respiration and apoptosis
Autor:
Wesley Freppel, Anaïs Anton, Zaynab Nouhi, Clément Mazeaud, Claudia Gilbert, Nicolas Tremblay, Viviana Andrea Barragan Torres, Aïssatou Aïcha Sow, Xavier Laulhé, Alain Lamarre, Ian Gaël Rodrigue-Gervais, Andreas Pichlmair, Pietro Scaturro, Laura Hulea, Laurent Chatel-Chaix
With no therapeutics available, there is an urgent need to better understand the pathogenesis of flaviviruses which constitute a threat to public health worldwide. During infection, dengue virus (DENV) and Zika virus (ZIKV), two flaviviruses induce a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bcf7a164462cc0746291be64badd2a7
https://doi.org/10.1101/2023.03.09.531853
https://doi.org/10.1101/2023.03.09.531853
Autor:
Katie Fooks, Gabriela Galicia-Vazquez, Alejandro Schcolnik-Cabrera, Victor Gife, Zaynab Nouhi, William WL Poon, Vincent Luo, Raquel Aloyz, Alexandre Orthwein, Laura Hulea, François E Mercier
Background Acute myeloid leukemia (AML) is an aggressive hematological cancer resulting from uncontrolled proliferation of differentiation-blocked myeloid cells. Seventy percent of AML patients are currently not cured with available treatments, highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d70d8c735ce142ceb9de8e4e58484e9
https://doi.org/10.21203/rs.3.rs-1696855/v1
https://doi.org/10.21203/rs.3.rs-1696855/v1
Publikováno v:
FEBS Letters. 584:923-928
We found that both wild type and Nrf3 (NF-E2-related factor 3) deficient mice are sensitive to BHT single administration exhibiting respiratory distress and considerably lose body weight following treatment. At time of sacrifice, the BHT-treated Nrf3
Autor:
Jean-Jacques Lebrun, Naila Chughtai, Strachan Hartley, Eftihia Cocolakis, Zaynab Nouhi, Suhad Ali
Publikováno v:
Cancer Research. 66:1824-1832
Prolactin hormone (PRL) is well characterized as a terminal differentiation factor for mammary epithelial cells and as an autocrine growth/survival factor in breast cancer cells. However, this function of PRL may not fully signify its role in breast
Autor:
Lucie Canaff, Svetlana Pidasheva, Bing Yang, Zaynab Nouhi, Geoffrey N. Hendy, Cuihong Wei, Donald Zimmerman, Carla Z. Minutti, David Ec Cole
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 88:3674-3681
De novo activating mutations in the calcium-sensing receptor (CASR) gene are a common cause of sporadic isolated hypoparathyroidism. Here, we describe a family in which two affected siblings were found to be heterozygous for a novel F788L mutation in
Publikováno v:
Experimental hematology. 40(5)
The transcription factor p45 nuclear factor-erythroid−derived 2 (NF-E2) plays major roles in erythroid and megakaryocytic lineages. Here, we investigated the role of p45 NF-E2 in erythroid differentiation in vivo. Absence of p45 NF-E2 in mice leads
Publikováno v:
FEBS letters. 581(28)
We have analysed the molecular and cellular regulation of the basic-leucine zipper (bZIP) transcription factor Nrf3 (NFE2-Related Factor 3). Cycloheximide studies revealed a rapid turnover of Nrf3. We showed that the proteasome inhibitor MG-132 incre
Publikováno v:
The Journal of biological chemistry. 278(52)
The protein tyrosine phosphatase SHP-2 is an important regulator of the Janus kinase-2 (Jak2)/signal transducer and activator of transcription (Stat) pathway downstream of the cytokine/prolactin receptor family. We report that SHP-2 dephosphorylates
Publikováno v:
Cancer Research. 69:B33-B33
In this study, we investigated the role of the transcription factor Nrf3 in chemical carcinogenesis induced by benzo[a]pyrene, a common carcinogen found in cigarette smoke, car exhaust and charcoal-grilled meats. Wild type and Nrf3-deficient mice wer