Immunogenicity and Protective Efficacy of a Single Intranasal Dose Vectored Vaccine Based on Sendai Virus (Moscow Strain) against SARS-CoV-2 Variant of Concern.

Autor: Kochneva GV; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia., Kudrov GA; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia., Zainutdinov SS; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia., Shulgina IS; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia., Shipovalov AV; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia., Zaykovskaya AV; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia., Borgoyakova MB; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia., Starostina EV; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia., Bodnev SA; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia., Sivolobova GF; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia., Grazhdantseva AA; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia., Ivkina DI; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia., Zadorozhny AM; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia., Karpenko LI; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia., P'yankov OV; Federal Budgetary Research Institution State Research Center of Virology and Biotechnology «Vector», Rospotrebnadzor, 630559 Koltsovo, Russia.

Publikováno v: Vaccines [Vaccines (Basel)] 2024 Jul 16; Vol. 12 (7). Date of Electronic Publication: 2024 Jul 16.

The Potential of Usnic-Acid-Based Thiazolo-Thiophenes as Inhibitors of the Main Protease of SARS-CoV-2 Viruses.

Autor: Yarovaya OI; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Filimonov AS; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Baev DS; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia.; Synchrotron Radiation Facility SKIF, G.K. Boreskov Institute of Catalysis SB RAS, 630559 Koltsovo, Russia., Borisevich SS; Synchrotron Radiation Facility SKIF, G.K. Boreskov Institute of Catalysis SB RAS, 630559 Koltsovo, Russia.; Laboratory of Chemical Physics, Ufa Institute of Chemistry, Ufa Federal Research Centre, 450078 Ufa, Russia., Zaykovskaya AV; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia., Chirkova VY; Institute of Biology and Biotechnology, Altay State University, 656049 Barnaul, Russia., Marenina MK; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Meshkova YV; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Belenkaya SV; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia.; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia., Shcherbakov DN; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia.; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia.; Institute of Biology and Biotechnology, Altay State University, 656049 Barnaul, Russia., Gureev MA; Laboratory of Bio- and Cheminformatics, St. Petersburg School of Physics, Mathematics and Computer Science, HSE University, 194100 St. Peterburg, Russia., Luzina OA; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Pyankov OV; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Koltsovo, Russia., Salakhutdinov NF; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Khvostov MV; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia.

Publikováno v: Viruses [Viruses] 2024 Jan 31; Vol. 16 (2). Date of Electronic Publication: 2024 Jan 31.

[Intranasal vaccine against COVID-19 based on a recombinant variant of the Sendai virus (Paramyxoviridae: Respirovirus ) strain Moscow].

Autor: Kudrov GA; State Research Center of Virology and Biotechnology 'Vector' of Rospotrebnadzor., Zainutdinov SS; State Research Center of Virology and Biotechnology 'Vector' of Rospotrebnadzor., Grazhdantseva AA; State Research Center of Virology and Biotechnology 'Vector' of Rospotrebnadzor., Shipovalov AV; State Research Center of Virology and Biotechnology 'Vector' of Rospotrebnadzor., Sivolobova GF; State Research Center of Virology and Biotechnology 'Vector' of Rospotrebnadzor., Semenova AV; State Research Center of Virology and Biotechnology 'Vector' of Rospotrebnadzor., Merkuleva IA; State Research Center of Virology and Biotechnology 'Vector' of Rospotrebnadzor., Shcherbakov DN; State Research Center of Virology and Biotechnology 'Vector' of Rospotrebnadzor., Taranov OS; State Research Center of Virology and Biotechnology 'Vector' of Rospotrebnadzor., Zaykovskaya AV; State Research Center of Virology and Biotechnology 'Vector' of Rospotrebnadzor., Shulgina IS; State Research Center of Virology and Biotechnology 'Vector' of Rospotrebnadzor., Pyankov OV; State Research Center of Virology and Biotechnology 'Vector' of Rospotrebnadzor., Kochneva GV; State Research Center of Virology and Biotechnology 'Vector' of Rospotrebnadzor.

Publikováno v: Voprosy virusologii [Vopr Virusol] 2023 Jul 06; Vol. 68 (3), pp. 215-227. Date of Electronic Publication: 2023 Jul 06.

Immunogenicity of the DNA/Protein Combined Vaccine against COVID-19.

Autor: Borgoyakova MB; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia. borgoyakova_mb@vector.nsc.ru., Karpenko LI; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Merkulyeva IA; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Shcherbakov DN; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Rudometov AP; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Starostina EV; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Shanshin DV; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Isaeva AA; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Nesmeyanova VS; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Volkova NV; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Belenkaya SV; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Volosnikova EA; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Zadorozhny AM; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Orlova LA; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Zaykovskaya AV; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Pyankov OV; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Bazhan SI; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia., Ilyichev AA; State Research Center of Virology and Biotechnology 'VECTOR', Federal Service for the Oversight of Consumer Protection and Welfare, Koltsovo, Novosibirsk region, Russia.

Publikováno v: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2022 Dec; Vol. 174 (2), pp. 246-249. Date of Electronic Publication: 2023 Jan 04.

(+)-Usnic Acid and Its Derivatives as Inhibitors of a Wide Spectrum of SARS-CoV-2 Viruses.

Autor: Filimonov AS; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Yarovaya OI; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Zaykovskaya AV; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Yekaterinburg, Russia., Rudometova NB; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Yekaterinburg, Russia., Shcherbakov DN; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Yekaterinburg, Russia., Chirkova VY; Department of Physical-Chemistry Biology and Biotechnology, Altay State University, 656049 Barnaul, Russia., Baev DS; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Borisevich SS; Laboratory of Chemical Physics, Ufa Institute of Chemistry Ufa Federal Research Center, 450078 Ufa, Russia., Luzina OA; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia., Pyankov OV; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Yekaterinburg, Russia., Maksyutov RA; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559 Yekaterinburg, Russia., Salakhutdinov NF; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, 630090 Novosibirsk, Russia.

Publikováno v: Viruses [Viruses] 2022 Sep 29; Vol. 14 (10). Date of Electronic Publication: 2022 Sep 29.