Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Zaydah R, de Laurent"'
Autor:
D. Collins Owuor, Zaydah R. de Laurent, John W. Oketch, Nickson Murunga, James R. Otieno, Grace Nabakooza, Sandra S. Chaves, D. James Nokes, Charles N. Agoti
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The role of sub-Saharan Africa in the global spread of influenza viruses remains unclear due to insufficient spatiotemporal sequence data. Here, we analyzed 222 codon-complete sequences of influenza A viruses (IAVs) sampled between 2011 and
Externí odkaz:
https://doaj.org/article/ece55953f99d471dbfa110a62280e388
Autor:
D. Collins Owuor, Zaydah R. de Laurent, Bryan O. Nyawanda, Gideon O. Emukule, Rebecca Kondor, John R. Barnes, D. James Nokes, Charles N. Agoti, Sandra S. Chaves
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Influenza viruses undergo rapid evolutionary changes, which requires continuous surveillance to monitor for genetic and potential antigenic changes in circulating viruses that can guide control and prevention decision making. We sequenced an
Externí odkaz:
https://doaj.org/article/29e15b8e4c074563952b391663f94dbc
Autor:
Grace Nabakooza, D. Collins Owuor, Zaydah R. de Laurent, Ronald Galiwango, Nicholas Owor, John T. Kayiwa, Daudi Jjingo, Charles N. Agoti, D. James Nokes, David P. Kateete, John M. Kitayimbwa, Simon D. W. Frost, Julius J. Lutwama
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Genetic characterisation of circulating influenza viruses directs annual vaccine strain selection and mitigation of infection spread. We used next-generation sequencing to locally generate whole genomes from 116 A(H1N1)pdm09 and 118 A(H3N2)
Externí odkaz:
https://doaj.org/article/3815ce0a46814b52a4389c513f8808ce
Autor:
Kelvin M. Kimenyi, Kevin Wamae, Joyce M. Ngoi, Zaydah R. de Laurent, Leonard Ndwiga, Victor Osoti, George Obiero, Abdirahman I. Abdi, Philip Bejon, Lynette Isabella Ochola-Oyier
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-10 (2022)
Abstract Background High levels of genetic diversity are common characteristics of Plasmodium falciparum parasite populations in high malaria transmission regions. There has been a decline in malaria transmission intensity over 12 years of surveillan
Externí odkaz:
https://doaj.org/article/31c27094c07c43a58f1e7c979315784c
Autor:
George Githinji, Zaydah R. de Laurent, Khadija Said Mohammed, Donwilliams O. Omuoyo, Peter M. Macharia, John M. Morobe, Edward Otieno, Samson M. Kinyanjui, Ambrose Agweyu, Eric Maitha, Ben Kitole, Thani Suleiman, Mohamed Mwakinangu, John Nyambu, John Otieno, Barke Salim, Kadondi Kasera, John Kiiru, Rashid Aman, Edwine Barasa, George Warimwe, Philip Bejon, Benjamin Tsofa, Lynette Isabella Ochola-Oyier, D. James Nokes, Charles N. Agoti
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
SARS-CoV-2 was first detected in Kenya in March 2020 and there was evidence of local transmission in the following months. Here, the authors characterise the early stages of the epidemic in coastal Kenya using phylogenetics and find evidence of multi
Externí odkaz:
https://doaj.org/article/a034766731d140dba3068aa4fac4efdf
Autor:
Charles N Agoti, Lynette Isabella Ochola-Oyier, Simon Dellicour, Khadija Said Mohammed, Arnold W Lambisia, Zaydah R de Laurent, John M Morobe, Maureen W Mburu, Donwilliams O Omuoyo, Edidah M Ongera, Leonard Ndwiga, Eric Maitha, Benson Kitole, Thani Suleiman, Mohamed Mwakinangu, John K Nyambu, John Otieno, Barke Salim, Jennifer Musyoki, Nickson Murunga, Edward Otieno, John N Kiiru, Kadondi Kasera, Patrick Amoth, Mercy Mwangangi, Rashid Aman, Samson Kinyanjui, George Warimwe, My Phan, Ambrose Agweyu, Matthew Cotten, Edwine Barasa, Benjamin Tsofa, D James Nokes, Philip Bejon, George Githinji
Publikováno v:
eLife, Vol 11 (2022)
Background: Detailed understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) regional transmission networks within sub-Saharan Africa is key for guiding local public health interventions against the pandemic. Methods: Here, we a
Externí odkaz:
https://doaj.org/article/259b5b21630f4e3095f4df0de588263d
Autor:
Doris K. Nyamwaya, Mark Otiende, Donwilliams O. Omuoyo, George Githinji, Henry K. Karanja, John N. Gitonga, Zaydah R. de Laurent, James R. Otieno, Rosemary Sang, Everlyn Kamau, Stanley Cheruiyot, Edward Otieno, Charles N. Agoti, Philip Bejon, Samuel M. Thumbi, George M. Warimwe
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Chikungunya fever (CHIKF) was first described in Tanzania in 1952. Several epidemics including East Africa have occurred, but there are no descriptions of longitudinal surveillance of endemic disease. Here, we estimate the inciden
Externí odkaz:
https://doaj.org/article/49b1c03fa75a4a7589d0a62604cacec1
Autor:
Rosie J. Crane, Edward P.K. Parker, Simon Fleming, Agnes Gwela, Wilson Gumbi, Joyce M. Ngoi, Zaydah R. de Laurent, Emily Nyatichi, Moses Ngari, Juliana Wambua, Holm H. Uhlig, James A. Berkley
Publikováno v:
EClinicalMedicine, Vol 47, Iss , Pp 101403- (2022)
Summary: Background: Environmental Enteric Dysfunction (EED) is a chronic intestinal inflammatory disorder of unclear aetiology prevalent amongst children in low-income settings and associated with stunting. We aimed to characterise development of EE
Externí odkaz:
https://doaj.org/article/700cfe624c1f44a580123c5922aec60d
Autor:
Doris K Nyamwaya, Mark Otiende, Lilian Mwango, Symon M Kariuki, Berrick Otieno, Donwilliams O Omuoyo, George Githinji, Barnes S Kitsao, Henry K Karanja, John N Gitonga, Zaydah R de Laurent, Alun Davies, Salim Mwarumba, Charles N Agoti, Samuel M Thumbi, Mainga M Hamaluba, Charles R Newton, Philip Bejon, George M Warimwe
Publikováno v:
PLoS Medicine, Vol 19, Iss 5, p e1003994 (2022)
BackgroundNeurological complications due to chikungunya virus (CHIKV) infection have been described in different parts of the world, with children being disproportionately affected. However, the burden of CHIKV-associated neurological disease in Afri
Externí odkaz:
https://doaj.org/article/8686a85efdb64bf0b298b7aaded278f5
Autor:
Shadrack Mutua, Brian Bartilol, Shaban J. Mwangi, Debra Riako, Lydia Nyamako, Bonface M. Gichuki, Henry Karanja, Angela Karani, John N. Gitonga, Daisy Mugo, Brian Tawa, Wilson Gumbi, Wesley Cheruiyot, Metrine Tendwa, John K. Nyambu, Yiakon Sein, Thani Suleiman Thani, Shem O. Patta, Benson Kitole, Eric K. Maitha, Barke S. Muslih, Mohamed S. Mwakinangu, Philip Bejon, Benjamin Tsofa, Joyce U. Nyiro, John Ochieng Otieno, Leonard Ndwiga, Patience Kiyuka, Johnstone Makale, Kevin Wamae, Victor Osoti, John Mwita Morobe, Calleb Odundo, Arnold W. Lambisia, Martin Mutunga, Salim Mwarumba, Lynette Isabella Ochola-Oyier, Charles N. Agoti, Clement Lewa, Elijah Gicheru, Jennifer Musyoki, Susan Njuguna, Horace Gumba, Domtila Kimani, Jedidah Mwacharo, Zaydah R. de Laurent, Khadija Said Mohammed, Robinson Cheruiyot, Donwilliams O. Omuoyo
Publikováno v:
Wellcome Open Research, Vol 5 (2022)
Background: The COVID-19 pandemic relies on real-time polymerase chain reaction (qRT-PCR) for the detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), to facilitate roll-out of patient care and infection control measures. There
Externí odkaz:
https://doaj.org/article/7bfed2fab94a4894a12683a69695a1a8