Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Zayd M Khaliq"'
Publikováno v:
eLife, Vol 9 (2020)
Axons of dopaminergic neurons innervate the striatum where they contribute to movement and reinforcement learning. Past work has shown that striatal GABA tonically inhibits dopamine release, but whether GABA-A receptors directly modulate transmission
Externí odkaz:
https://doaj.org/article/95c2c2e726d44c438b3b9e9b21e8fcf7
Autor:
Fabian Philippart, Zayd M Khaliq
Publikováno v:
eLife, Vol 7 (2018)
Dopamine (D2) receptors provide autoinhibitory feedback onto dopamine neurons through well-known interactions with voltage-gated calcium channels and G protein-coupled inwardly-rectifying potassium (GIRK) channels. Here, we reveal a third major effec
Externí odkaz:
https://doaj.org/article/d2d68ce1861a4d839803491fb537868c
Publikováno v:
eLife, Vol 5 (2016)
Little is known about the density and function of dendritic spines on midbrain dopamine neurons, or the relative contribution of spine and shaft synapses to excitability. Using Ca2+ imaging, glutamate uncaging, fluorescence recovery after photobleach
Externí odkaz:
https://doaj.org/article/9bea0d7d5c9b42f98bcc5bd9b540888b
Autor:
Kathleen Carmichael, Rebekah C. Evans, Elena Lopez, Lixin Sun, Mantosh Kumar, Jinhui Ding, Zayd M. Khaliq, Huaibin Cai
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2021)
Dopamine is an important chemical messenger in the brain, which modulates movement, reward, motivation, and memory. Different populations of neurons can produce and release dopamine in the brain and regulate different behaviors. Here we focus our dis
Externí odkaz:
https://doaj.org/article/5c7a63cf953c42c69167502c8cc9e988
Autor:
Paul F. Kramer, Samuel Brill-Weil, Alex C. Cummins, Renshu Zhang, Gisela A. Camacho-Hernandez, Amy H. Newman, Mark A. Eldridge, Bruno B. Averbeck, Zayd M. Khaliq
SummaryTransmission from striatal cholinergic interneurons (CINs) controls dopamine release through nicotinic acetylcholine receptors (nAChRs) on dopaminergic axons. Anatomical studies suggest that cholinergic terminals signal predominantly through n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e6dc7da69002a0a6c0ca1fd126c72a6
https://doi.org/10.1101/2022.03.25.485828
https://doi.org/10.1101/2022.03.25.485828
Autor:
Zayd M. Khaliq, Rebekah C. Evans, Emily L Twedell, Renshu Zhang, Jefferson Ascencio, Manhua Zhu
Publikováno v:
Cell Rep
Substantia nigra (SNc) dopaminergic neurons respond to aversive stimuli with inhibitory pauses in firing followed by transient rebound activation. We tested integration of inhibitory synaptic inputs onto SNc neurons from genetically defined populatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229bc48f3dae4ff5253e88fcdb685e2e
https://europepmc.org/articles/PMC9887718/
https://europepmc.org/articles/PMC9887718/
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Axons of dopaminergic neurons innervate the striatum where they contribute to movement and reinforcement learning. Past work has shown that striatal GABA tonically inhibits dopamine release, but whether GABA-A receptors directly modulate transmission
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814bb6f80dd449b1597b665a990e260c
https://doi.org/10.7554/elife.55729
https://doi.org/10.7554/elife.55729
Axons of midbrain dopaminergic neurons innervate the striatum where they contribute to movement and reinforcement learning. Past work has shown that striatal GABA tonically inhibits dopamine release, but whether GABA-A receptors directly modulate tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964186783068549e82caa9b84c668aa8
https://doi.org/10.1101/2020.02.09.941179
https://doi.org/10.1101/2020.02.09.941179
Autor:
Zayd M. Khaliq, Manhua Zhu, Renshu Zhang, Emily L Twedell, Jefferson Ascencio, Rebekah C. Evans
Substania nigra (SNc) dopaminergic neurons show a pause-rebound firing pattern in response to aversive events. Because these neurons integrate information from predominately inhibitory brain areas, it is important to determine which inputs functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c172ad0a4c00da3a5780f9c65729382
https://doi.org/10.1101/856617
https://doi.org/10.1101/856617