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Accuracy of the tuberculosis molecular bacterial load assay to diagnose and monitor response to anti-tuberculosis therapy: a longitudinal comparative study with standard-of-care smear microscopy, Xpert MTB/RIF Ultra, and culture in Uganda.

Autor: Musisi E; Division of Infection and Global Health, School of Medicine, University of St Andrews, St Andrews, UK; Infectious Diseases Research Collaboration, Kampala, Uganda., Wamutu S; Department of Biochemistry and Sports Sciences, Makerere University, Kampala, Uganda., Ssengooba W; BSL-3 Mycobacteriology Laboratory, Department of Medical Microbiology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda; Medical and Molecular Laboratories (MML), Kampala, Uganda., Kasiinga S; Infectious Diseases Research Collaboration, Kampala, Uganda., Sessolo A; Infectious Diseases Research Collaboration, Kampala, Uganda., Sanyu I; Infectious Diseases Research Collaboration, Kampala, Uganda., Kaswabuli S; Infectious Diseases Research Collaboration, Kampala, Uganda., Zawedde J; Infectious Diseases Research Collaboration, Kampala, Uganda., Byanyima P; Infectious Diseases Research Collaboration, Kampala, Uganda., Kia P; BSL-3 Mycobacteriology Laboratory, Department of Medical Microbiology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda., Muwambi W; BSL-3 Mycobacteriology Laboratory, Department of Medical Microbiology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda., Toskin DT; BSL-3 Mycobacteriology Laboratory, Department of Medical Microbiology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda., Kigozi E; BSL-3 Mycobacteriology Laboratory, Department of Medical Microbiology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda., Walbaum N; Division of Infection and Global Health, School of Medicine, University of St Andrews, St Andrews, UK., Dombay E; Division of Infection and Global Health, School of Medicine, University of St Andrews, St Andrews, UK., Legrady MB; School of Chemistry, University of St Andrews, St Andrews, UK., Ssemambo KD; BSL-3 Mycobacteriology Laboratory, Department of Medical Microbiology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda; Medical and Molecular Laboratories (MML), Kampala, Uganda., Joloba M; BSL-3 Mycobacteriology Laboratory, Department of Medical Microbiology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda; Medical and Molecular Laboratories (MML), Kampala, Uganda., Kuchaka D; Kilimanjaro Clinical Research Institute, Kilimanjaro, Tanzania., Worodria W; Infectious Diseases Research Collaboration, Kampala, Uganda., Huang L; Infectious Diseases Research Collaboration, Kampala, Uganda; Division of Pulmonary and Critical Care Medicine and Division of HIV, Infectious Diseases, and Global Medicine, University of California San Francisco, San Francisco, CA, USA., Gillespie SH; Division of Infection and Global Health, School of Medicine, University of St Andrews, St Andrews, UK., Sabiiti W; Division of Infection and Global Health, School of Medicine, University of St Andrews, St Andrews, UK. Electronic address: ws31@st-andrews.ac.uk.

Publikováno v: The Lancet. Microbe [Lancet Microbe] 2024 Apr; Vol. 5 (4), pp. e345-e354. Date of Electronic Publication: 2024 Mar 05.

Improved Diagnosis and Treatment Monitoring of Tuberculosis Using Stool and the Tuberculosis Bacterial Load Assay (TB-MBLA).

Autor: Musisi E; Division of Infection and Global Health, School of Medicine, University of St Andrews, St Andrews, UK.; Infectious Diseases Research Collaboration, Kampala, Uganda.; Adroit Biomedical & Bioentreprenuership Research Services, Kampala, Uganda., Mtafya B; National Institute for Medical Research - Mbeya Medical Research Centre, Mbeya, Tanzania., Wambi WS; School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda., Zawedde J; Infectious Diseases Research Collaboration, Kampala, Uganda., Sessolo A; Infectious Diseases Research Collaboration, Kampala, Uganda., Ssengooba W; School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda., Walbaum N; Division of Infection and Global Health, School of Medicine, University of St Andrews, St Andrews, UK., Ntinginya NE; National Institute for Medical Research - Mbeya Medical Research Centre, Mbeya, Tanzania., Gillespie SH; Division of Infection and Global Health, School of Medicine, University of St Andrews, St Andrews, UK., Sabiiti W; Division of Infection and Global Health, School of Medicine, University of St Andrews, St Andrews, UK. ws31@st-andrews.ac.uk.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2024; Vol. 2833, pp. 153-160.

Diagnostic accuracy of Xpert MTB/RIF Ultra and culture assays to detect Mycobacterium Tuberculosis using OMNIgene-sputum processed stool among adult TB presumptive patients in Uganda.

Autor: Sessolo A; Infectious Diseases Research Collaboration, Kampala, Uganda., Musisi E; Infectious Diseases Research Collaboration, Kampala, Uganda.; Department of Biochemistry and Sports Science, Makerere University, Kampala, Uganda.; Division of Infection and Global Health, School of Medicine, University of St. Andrews, Scotland, United Kingdom., Kaswabuli S; Infectious Diseases Research Collaboration, Kampala, Uganda., Zawedde J; Infectious Diseases Research Collaboration, Kampala, Uganda., Byanyima P; Infectious Diseases Research Collaboration, Kampala, Uganda., Sabiiti W; Division of Infection and Global Health, School of Medicine, University of St. Andrews, Scotland, United Kingdom., Walimbwa S; China Uganda Friendship Hospital Naguru, Kampala, Uganda., Ola J; China Uganda Friendship Hospital Naguru, Kampala, Uganda., Sanyu I; Infectious Diseases Research Collaboration, Kampala, Uganda., Lalitha R; Department of Internal Medicine, Makerere University College of Health Sciences, Kampala, Uganda., Kamya M; Infectious Diseases Research Collaboration, Kampala, Uganda., Davis L; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, United States of America.; Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT, United States of America., Worodria W; Infectious Diseases Research Collaboration, Kampala, Uganda., Huang L; Infectious Diseases Research Collaboration, Kampala, Uganda.; Division of Pulmonary and Critical Care Medicine, University of California San Francisco, San Francisco, CA, United States of America.; Division of HIV, Infectious Diseases and Global Medicine, University of California San Francisco, San Francisco, CA, United States of America.

Publikováno v: PloS one [PLoS One] 2023 Apr 21; Vol. 18 (4), pp. e0284041. Date of Electronic Publication: 2023 Apr 21 (Print Publication: 2023).

Accuracy of GenoQuick MTB test in detection of Mycobacterium tuberculosis in sputum from TB presumptive patients in Uganda.

Autor: Kaswabuli S; Infectious Diseases Research Collaboration, Kampala, Uganda., Musisi E; Division of Infection and Global Health, School of Medicine, University of St Andrews, St Andrews, UK., Byanyima P; Infectious Diseases Research Collaboration, Kampala, Uganda., Sessolo A; Infectious Diseases Research Collaboration, Kampala, Uganda., Sanyu I; Infectious Diseases Research Collaboration, Kampala, Uganda., Zawedde J; Infectious Diseases Research Collaboration, Kampala, Uganda., Worodria W; Infectious Diseases Research Collaboration, Kampala, Uganda., Huang L; Infectious Diseases Research Collaboration, Kampala, Uganda.; Division of HIV, Infectious Diseases & Global Medicine, University of California San Francisco, San Francisco, CA, USA.; Division of Pulmonary and Critical Care Medicine, University of California San Francisco, San Francisco, CA, USA., Okeng A; MBN Clinical Laboratories, Kampala, Uganda., Bwanga F; Department of Medical Microbiology, Makerere University College of Health Sciences, Kampala, Uganda.

Publikováno v: SAGE open medicine [SAGE Open Med] 2022 Aug 16; Vol. 10, pp. 20503121221116861. Date of Electronic Publication: 2022 Aug 16 (Print Publication: 2022).