Altered H3K4me3 profile at the TFAM promoter causes mitochondrial alterations in preadipocytes from first-degree relatives of type 2 diabetics

Autor: Michele Longo, Federica Zatterale, Rosa Spinelli, Jamal Naderi, Luca Parrillo, Pasqualina Florese, Cecilia Nigro, Alessia Leone, Augusta Moccia, Antonella Desiderio, Gregory A. Raciti, Claudia Miele, Ulf Smith, Francesco Beguinot

Publikováno v: Clinical Epigenetics, Vol 15, Iss 1, Pp 1-24 (2023)

Abstract Background First-degree relatives of type 2 diabetics (FDR) exhibit a high risk of developing type 2 diabetes (T2D) and feature subcutaneous adipocyte hypertrophy, independent of obesity. In FDR, adipose cell abnormalities contribute to earl

Externí odkaz: https://doaj.org/article/67d0a5fc91c74ab8832d99e8826746b5

Altered H3K4me3 profile at the TFAM promoter causes mitochondrial alterations in preadipocytes from first-degree relatives of type 2 diabetics.

Autor: Longo, Michele^1,2 (AUTHOR), Zatterale, Federica^1,2 (AUTHOR), Spinelli, Rosa^1,2 (AUTHOR), Naderi, Jamal² (AUTHOR), Parrillo, Luca² (AUTHOR), Florese, Pasqualina¹ (AUTHOR), Nigro, Cecilia² (AUTHOR), Leone, Alessia² (AUTHOR), Moccia, Augusta¹ (AUTHOR), Desiderio, Antonella^1,2 (AUTHOR), Raciti, Gregory A.^1,2 (AUTHOR) gregoryalexander.raciti@unina.it, Miele, Claudia² (AUTHOR), Smith, Ulf³ (AUTHOR), Beguinot, Francesco^1,2 (AUTHOR) beguino@unina.it

Publikováno v: Clinical Epigenetics. 9/7/2023, Vol. 15 Issue 1, p1-24. 24p.

Re-definition and supporting evidence toward Fanconi Anemia as a mitochondrial disease: Prospects for new design in clinical management

Autor: Pagano, Giovanni, Tiano, Luca, Pallardó, Federico V., Lyakhovich, Alex, Mukhopadhyay, Sudit S., Di Bartolomeo, Paolo, Zatterale, Adriana, Trifuoggi, Marco

Publikováno v: In Redox Biology April 2021 40

Epigenetic Reprogramming of the Inflammatory Response in Obesity and Type 2 Diabetes

Autor: Federica Zatterale, Gregory Alexander Raciti, Immacolata Prevenzano, Alessia Leone, Michele Campitelli, Veronica De Rosa, Francesco Beguinot, Luca Parrillo

Publikováno v: Biomolecules, Vol 12, Iss 7, p 982 (2022)

For the past several decades, the prevalence of obesity and type 2 diabetes (T2D) has continued to rise on a global level. The risk contributing to this pandemic implicates both genetic and environmental factors, which are functionally integrated by

Externí odkaz: https://doaj.org/article/9edcf110c91d47cc98ebc910c78e8b3b

Epigenetic Reprogramming of the Inflammatory Response in Obesity and Type 2 Diabetes.

Autor: Zatterale, Federica^1,2 (AUTHOR) federicazatterale@libero.it, Raciti, Gregory Alexander^1,2 (AUTHOR) gregoryraciti@gmail.com, Prevenzano, Immacolata^1,2 (AUTHOR) imma987@hotmail.it, Leone, Alessia^1,2 (AUTHOR) aleleone86@libero.it, Campitelli, Michele^1,2 (AUTHOR) m.campitelli@ieos.cnr.it, De Rosa, Veronica² (AUTHOR), Beguinot, Francesco^1,2 (AUTHOR) beguino@unina.it, Parrillo, Luca^1,2 (AUTHOR) beguino@unina.it

Publikováno v: Biomolecules (2218-273X). Jul2022, Vol. 12 Issue 7, pN.PAG-N.PAG. 20p.