Customizing chemotherapy in thoracic malignancies based on ERCC1 expression

Autor: Zarah Glad Zimling, Jan Nyrop Jakobsen, Adam Vilmar, Jens Benn Sørensen, Sandra Wallerek

Publikováno v: Lung Cancer Management. 2:295-307

SUMMARY Platinum-based chemotherapy regimens using cisplatin or carboplatin are the cornerstones of treatment for advanced non-small-cell lung cancer (NSCLC), small-cell lung cancer and malignant pleural mesothelioma. Despite being standard regimens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::397f7f1f607ff76b49287f9fdaba57f5
https://doi.org/10.2217/lmt.13.30

The diagnostic value of immunohistochemically detected methylthioadenosine phosphorylase deficiency in malignant pleural mesotheliomas

Autor: Anne Jørgensen, Eric Santoni-Rugiu, Zarah Glad Zimling

Publikováno v: Histopathology. 60:E96-E105

Zimling Z G, Jorgensen A & Santoni-Rugiu E (2012) Histopathology 60, E96–E105 The diagnostic value of immunohistochemically detected methylthioadenosine phosphorylase deficiency in malignant pleural mesotheliomas Aims: Malignant pleural mesotheliom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee1dc2505fd2aa8de23c7c87b375df02
https://doi.org/10.1111/j.1365-2559.2012.04196.x

MMSET Is Highly Expressed and Associated with Aggressiveness in Neuroblastoma

Autor: Ronald Simon, Maria Antonietta De Ioris, Lisa Leth Maroun, M Quarto, Henrik Daa Schrøder, Jens Vilstrup Johansen, Mette Rose Jørgensen, Eric Santoni-Rugiu, Kristian Helin, Guido Sauter, Zarah Glad Zimling, Bodil Laub Petersen, Julie Skotte, Michael Lees, Rossella Rota, Heidi Rye Hudlebusch, Catherine Rechnitzer

Publikováno v: Hudlebusch, H R, Skotte, J, Santoni-Rugiu, E, Zimling, Z G, Lees, M J, Simon, R, Sauter, G, Rota, R, De Ioris, M A, Quarto, M, Johansen, J V, Jørgensen, M, Rechnitzer, C M A, Maroun, L L, Schrøder, H, Petersen, B L & Helin, K 2011, ' MMSET is highly expressed and associated with aggressiveness in neuroblastoma ', Cancer Research, vol. 71, no. 12, pp. 4226-35 . https://doi.org/10.1158/0008-5472.CAN-10-3810

MMSET (WHSC1/NSD2) is a SET domain–containing histone lysine methyltransferase the expression of which is deregulated in a subgroup of multiple myelomas with the t(4;14)(p16;q32) translocation associated with poor prognosis. Recent studies have sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7ccac8d640f62c7fe6316a7965b91a
https://doi.org/10.1158/0008-5472.can-10-3810

High RRM1 Expression Is Associated with Adverse Outcome in Patients with Cisplatin/Vinorelbine-treated Malignant Pleural Mesothelioma

Autor: Zarah Glad Zimling, Eric Santoni-Rugiu, Cecilia Bech, Jens Benn Sørensen

Publikováno v: Publons
University of Copenhagen

A possible predictive impact of ribonucleotide-reductase subunit-1 (RRM1) on vinorelbine efficacy in non-small cell lung cancer (NSCLC) has been previously reported. The present study aimed to further explore this finding in malignant pleural mesothe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4447d0a63e206195706287b22defc09a
https://pubmed.ncbi.nlm.nih.gov/26637889

The diagnostic value of immunohistochemically detected methylthioadenosine phosphorylase deficiency in malignant pleural mesotheliomas

Autor: Zarah Glad, Zimling, Anne, Jørgensen, Eric, Santoni-Rugiu

Publikováno v: Histopathology. 60(6B)

Malignant pleural mesothelioma (MPM) often causes diagnostic difficulties for pathologists. We assessed whether loss of methylthioadenosine phosphorylase (MTAP), a key enzyme in the intracellular recycling of adenosine triphosphate (ATP) often delete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d069644477bccbe5d6e8e7bad7c2c4c6
https://pubmed.ncbi.nlm.nih.gov/22394205