High-frequency head impact causes chronic synaptic adaptation and long-term cognitive impairment in mice.

Autor: Sloley SS; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Main BS; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Winston CN; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Harvey AC; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Kaganovich A; Laboratory of Neurogenetics, National Institute of Aging, Bethesda, MD, USA., Korthas HT; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Caccavano AP; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, USA., Zapple DN; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Wu JY; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Partridge JG; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, USA., Cookson MR; Laboratory of Neurogenetics, National Institute of Aging, Bethesda, MD, USA., Vicini S; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, USA., Burns MP; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA. mark.burns@georgetown.edu.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA. mark.burns@georgetown.edu.

Publikováno v: Nature communications [Nat Commun] 2021 May 10; Vol. 12 (1), pp. 2613. Date of Electronic Publication: 2021 May 10.

Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma.

Autor: Winston CN; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Noël A; Department of Psychiatry and Neurosciences, Université Laval, Quebec City, Quebec, Canada., Neustadtl A; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Parsadanian M; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Barton DJ; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Chellappa D; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Wilkins TE; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Alikhani AD; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Zapple DN; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Villapol S; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Planel E; Department of Psychiatry and Neurosciences, Université Laval, Quebec City, Quebec, Canada; Research Center of CHU of Québec, Neurosciences, Quebec, Canada. Electronic address: emmanuel@planel.org., Burns MP; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia. Electronic address: mpb37@georgetown.edu.

Publikováno v: The American journal of pathology [Am J Pathol] 2016 Mar; Vol. 186 (3), pp. 552-67. Date of Electronic Publication: 2016 Feb 05.

Controlled cortical impact results in an extensive loss of dendritic spines that is not mediated by injury-induced amyloid-beta accumulation.

Autor: Winston CN; 1 Department of Neuroscience, Laboratory for Brain Injury and Dementia, Georgetown University Medical Center , Washington, DC., Chellappa D, Wilkins T, Barton DJ, Washington PM, Loane DJ, Zapple DN, Burns MP

Publikováno v: Journal of neurotrauma [J Neurotrauma] 2013 Dec 01; Vol. 30 (23), pp. 1966-72. Date of Electronic Publication: 2013 Oct 12.

Fluid-percussion-induced traumatic brain injury model in rats.

Autor: Kabadi SV; Department of Anesthesiology and the Center for Shock, Trauma and Anesthesiology Research (STAR), School of Medicine, Baltimore, Maryland, USA., Hilton GD, Stoica BA, Zapple DN, Faden AI

Publikováno v: Nature protocols [Nat Protoc] 2010 Sep; Vol. 5 (9), pp. 1552-63. Date of Electronic Publication: 2010 Aug 19.