High-frequency head impact causes chronic synaptic adaptation and long-term cognitive impairment in mice.

Autor: Sloley SS; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Main BS; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Winston CN; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Harvey AC; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Kaganovich A; Laboratory of Neurogenetics, National Institute of Aging, Bethesda, MD, USA., Korthas HT; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Caccavano AP; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, USA., Zapple DN; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Wu JY; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA., Partridge JG; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, USA., Cookson MR; Laboratory of Neurogenetics, National Institute of Aging, Bethesda, MD, USA., Vicini S; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA.; Department of Pharmacology and Physiology, Georgetown University Medical Center, Washington, DC, USA., Burns MP; Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, DC, USA. mark.burns@georgetown.edu.; Department of Neuroscience, Georgetown University Medical Center, Washington, DC, USA. mark.burns@georgetown.edu.

Publikováno v: Nature communications [Nat Commun] 2021 May 10; Vol. 12 (1), pp. 2613. Date of Electronic Publication: 2021 May 10.

An affordable and open-source tool for mouse behavioral studies-pyControl in an undergraduate research setting.

Autor: Coller, Alexa M.¹, Alpern, Emma C.¹, Clinton, Kambrie E.¹, Alvarado Estrada, María L.¹, Emmons, Eric B.² eric.emmons@drake.edu

Publikováno v: Bios. 2024, Vol. 95 Issue 3, p176-182. 7p.

A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury.

Autor: Main BS; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center., Sloley SS; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center., Villapol S; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center., Zapple DN; University Information Systems, Division of Research Technologies, Georgetown University., Burns MP; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center; mpb37@georgetown.edu.

Publikováno v: Journal of visualized experiments : JoVE [J Vis Exp] 2017 Jun 20 (124). Date of Electronic Publication: 2017 Jun 20.

Extension domain of amyloid processor protein inhibits amyloidogenic cleavage and balances neural activity in a traumatic brain injury mouse model.

Autor: Xie, Zhenxing^1,2 (AUTHOR), Li, Tianyu^1,2 (AUTHOR), Su, Wei^1,2 (AUTHOR), Lou, Yanyun^1,2 (AUTHOR), Zhang, Yongsheng^1,2 (AUTHOR), Zhou, Xiyuan¹ (AUTHOR), Li, Zhanfei^1,2 (AUTHOR), Bai, Xiangjun^1,2 (AUTHOR) 709261538@qq.com, Liu, Xinghua^1,2 (AUTHOR) liu_xingh@126.com

Publikováno v: CNS Neuroscience & Therapeutics. Feb2024, Vol. 30 Issue 2, p1-16. 16p.

Dendritic Spine Loss and Chronic White Matter Inflammation in a Mouse Model of Highly Repetitive Head Trauma.

Autor: Winston CN; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Noël A; Department of Psychiatry and Neurosciences, Université Laval, Quebec City, Quebec, Canada., Neustadtl A; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Parsadanian M; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Barton DJ; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Chellappa D; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Wilkins TE; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Alikhani AD; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Zapple DN; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Villapol S; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia., Planel E; Department of Psychiatry and Neurosciences, Université Laval, Quebec City, Quebec, Canada; Research Center of CHU of Québec, Neurosciences, Quebec, Canada. Electronic address: emmanuel@planel.org., Burns MP; Laboratory for Brain Injury and Dementia, Department of Neuroscience, Georgetown University Medical Center, Washington, District of Columbia. Electronic address: mpb37@georgetown.edu.

Publikováno v: The American journal of pathology [Am J Pathol] 2016 Mar; Vol. 186 (3), pp. 552-67. Date of Electronic Publication: 2016 Feb 05.