IGF-1 Gene Transfer Modifies Inflammatory Environment and Gene Expression in the Caudate-Putamen of Aged Female Rat Brain.

Autor: Falomir-Lockhart E; Laboratorio de Bioquímica del Envejecimiento, Instituto de Investigaciones Bioquímicas de La Plata (INIBIOLP), Facultad de Ciencias Médicas, UNLP-CONICET, Av. 60 s/n., La Plata, CP1900, Buenos Aires, Argentina., Dolcetti FJC; Laboratorio de Bioquímica del Envejecimiento, Instituto de Investigaciones Bioquímicas de La Plata (INIBIOLP), Facultad de Ciencias Médicas, UNLP-CONICET, Av. 60 s/n., La Plata, CP1900, Buenos Aires, Argentina., Herrera ML; Instituto de Farmacología Experimental de Córdoba-CONICET, Departamento de Farmacología, Facultad de Ciencias Químicas, UNC-CONICET, CP500, Córdoba, Argentina., Pennini J; Laboratorio de Bioquímica del Envejecimiento, Instituto de Investigaciones Bioquímicas de La Plata (INIBIOLP), Facultad de Ciencias Médicas, UNLP-CONICET, Av. 60 s/n., La Plata, CP1900, Buenos Aires, Argentina., Zappa Villar MF; Laboratorio de Bioquímica del Envejecimiento, Instituto de Investigaciones Bioquímicas de La Plata (INIBIOLP), Facultad de Ciencias Médicas, UNLP-CONICET, Av. 60 s/n., La Plata, CP1900, Buenos Aires, Argentina., Salinas G; NGS- Integrative Genomics Core Unit (NIG), Institute of Human Genetics, University Medical Center Göttingen (UMG), Göttingen, Germany., Portiansky E; Laboratorio de Análisis de Imágenes (LAI), Facultad de Ciencias Veterinarias, UNLP, La Plata, Argentina., Spittau B; Institute of Anatomy, University of Rostock, Rostock, Germany.; Anatomy and Cell Biology, Medical School OWL, Bielefeld University, Bielefeld, Germany., Lacunza E; Centro de Investigaciones Inmunológicas Básicas Y Aplicadas (CINIBA), Facultad de Ciencias Médicas, Universidad Nacional de La Plata, La Plata, CP1900, Argentina., Hereñú CB; Instituto de Farmacología Experimental de Córdoba-CONICET, Departamento de Farmacología, Facultad de Ciencias Químicas, UNC-CONICET, CP500, Córdoba, Argentina. claudia.herenu@unc.edu.ar., Bellini MJ; Laboratorio de Bioquímica del Envejecimiento, Instituto de Investigaciones Bioquímicas de La Plata (INIBIOLP), Facultad de Ciencias Médicas, UNLP-CONICET, Av. 60 s/n., La Plata, CP1900, Buenos Aires, Argentina. mariajosebellini@yahoo.com.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2022 Jun; Vol. 59 (6), pp. 3337-3352. Date of Electronic Publication: 2022 Mar 19.

Adenovirus-Mediated Transduction of Insulin-Like Growth Factor 1 Protects Hippocampal Neurons from the Toxicity of Aβ Oligomers and Prevents Memory Loss in an Alzheimer Mouse Model.

Autor: Selles MC; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Fortuna JTS; Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Zappa-Villar MF; Institute of Biochemical Research (INIBIOLP) - National Scientific and Technical Research Council (CONICET) - School of Medical Sciences, National University of La Plata (UNLP), La Plata, Argentina., de Faria YPR; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Souza AS; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Suemoto CK; Discipline of Geriatrics, University of São Paulo Medical School, Sao Paulo, Brazil.; LIM-22, Department of Pathology, University of São Paulo Medical School, Sao Paulo, Brazil., Leite REP; Discipline of Geriatrics, University of São Paulo Medical School, Sao Paulo, Brazil.; LIM-22, Department of Pathology, University of São Paulo Medical School, Sao Paulo, Brazil., Rodriguez RD; LIM-22, Department of Pathology, University of São Paulo Medical School, Sao Paulo, Brazil.; Department of Neurology, University of São Paulo Medical School, Sao Paulo, Brazil., Grinberg LT; LIM-22, Department of Pathology, University of São Paulo Medical School, Sao Paulo, Brazil.; Department of Neurology, Memory and Aging Center, University of California San Francisco, San Francisco, CA, USA., Reggiani PC; Institute of Biochemical Research (INIBIOLP) - National Scientific and Technical Research Council (CONICET) - School of Medical Sciences, National University of La Plata (UNLP), La Plata, Argentina., Ferreira ST; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. ferreira@bioqmed.ufrj.br.; Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Av. Carlos Chagas Filho 373, Room C-31, Cidade Universitária, Rio de Janeiro, RJ, 21941-590, Brazil. ferreira@bioqmed.ufrj.br.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2020 Mar; Vol. 57 (3), pp. 1473-1483. Date of Electronic Publication: 2019 Nov 23.

Mesenchymal Stem Cells Therapy Improved the Streptozotocin-Induced Behavioral and Hippocampal Impairment in Rats.

Autor: Zappa Villar MF; Institute for Biochemical Research (INIBIOLP) - National Scientific and Technical Research Council (CONICET) - School of Medical Sciences, National University of La Plata (UNLP), CC 455, Zip 1900, La Plata, Argentina. mfzappa@med.unlp.edu.ar., López Hanotte J; Institute for Biochemical Research (INIBIOLP) - National Scientific and Technical Research Council (CONICET) - School of Medical Sciences, National University of La Plata (UNLP), CC 455, Zip 1900, La Plata, Argentina., Pardo J; Institute for Biochemical Research (INIBIOLP) - National Scientific and Technical Research Council (CONICET) - School of Medical Sciences, National University of La Plata (UNLP), CC 455, Zip 1900, La Plata, Argentina., Morel GR; Institute for Biochemical Research (INIBIOLP) - National Scientific and Technical Research Council (CONICET) - School of Medical Sciences, National University of La Plata (UNLP), CC 455, Zip 1900, La Plata, Argentina., Mazzolini G; Gene Therapy Laboratory, IIMT, Facultad de Ciencias Biomédicas, CONICET-Universidad Austral, Buenos Aires, Argentina., García MG; Gene Therapy Laboratory, IIMT, Facultad de Ciencias Biomédicas, CONICET-Universidad Austral, Buenos Aires, Argentina., Reggiani PC; Institute for Biochemical Research (INIBIOLP) - National Scientific and Technical Research Council (CONICET) - School of Medical Sciences, National University of La Plata (UNLP), CC 455, Zip 1900, La Plata, Argentina. paulareggiani@conicet.gov.ar.; Department of Cytology, Histology and Embryology B, School of Medical Sciences, UNLP, La Plata, Argentina. paulareggiani@conicet.gov.ar.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2020 Feb; Vol. 57 (2), pp. 600-615. Date of Electronic Publication: 2019 Aug 10.

Umbilical Cord Cell Therapy Improves Spatial Memory in Aging Rats.

Autor: Lehmann M; INIBIOLP-Pathology B, School of Medicine, National University of La Plata, Calles 60 y 120, 1900, La Plata, Argentina.; Department of Histology and of Embryology B, School of Medicine, National University of La Plata, La Plata, Buenos Aires, Argentina., Zappa-Villar MF; INIBIOLP-Pathology B, School of Medicine, National University of La Plata, Calles 60 y 120, 1900, La Plata, Argentina.; Department of Histology and of Embryology B, School of Medicine, National University of La Plata, La Plata, Buenos Aires, Argentina., García MG; Gene Therapy Laboratory, IIMT, Facultad de Ciencias Biomédicas, CONICET, Universidad Austral, Buenos Aires, Argentina., Mazzolini G; Gene Therapy Laboratory, IIMT, Facultad de Ciencias Biomédicas, CONICET, Universidad Austral, Buenos Aires, Argentina., Canatelli-Mallat M; INIBIOLP-Pathology B, School of Medicine, National University of La Plata, Calles 60 y 120, 1900, La Plata, Argentina.; Department of Histology and of Embryology B, School of Medicine, National University of La Plata, La Plata, Buenos Aires, Argentina., Morel GR; INIBIOLP-Pathology B, School of Medicine, National University of La Plata, Calles 60 y 120, 1900, La Plata, Argentina.; Department of Histology and of Embryology B, School of Medicine, National University of La Plata, La Plata, Buenos Aires, Argentina., Reggiani PC; INIBIOLP-Pathology B, School of Medicine, National University of La Plata, Calles 60 y 120, 1900, La Plata, Argentina.; Department of Histology and of Embryology B, School of Medicine, National University of La Plata, La Plata, Buenos Aires, Argentina., Goya RG; INIBIOLP-Pathology B, School of Medicine, National University of La Plata, Calles 60 y 120, 1900, La Plata, Argentina. goya@isis.unlp.edu.ar.; Department of Histology and of Embryology B, School of Medicine, National University of La Plata, La Plata, Buenos Aires, Argentina. goya@isis.unlp.edu.ar.

Publikováno v: Stem cell reviews and reports [Stem Cell Rev Rep] 2019 Aug; Vol. 15 (4), pp. 612-617.

A new adenovector system for implementing thymulin gene therapy for inflammatory disorders.

Autor: Zappa-Villar MF; Institute for Biochemical Research-Histology B-Pathology B, Faculty of Medicine, National University of La Plata, Argentina., López-León M; Institute for Biochemical Research-Histology B-Pathology B, Faculty of Medicine, National University of La Plata, Argentina., Pardo J; Institute for Biochemical Research-Histology B-Pathology B, Faculty of Medicine, National University of La Plata, Argentina., Costa M; Institute for Biochemical Research-Histology B-Pathology B, Faculty of Medicine, National University of La Plata, Argentina., Crespo R; Institute for Biochemical Research-Histology B-Pathology B, Faculty of Medicine, National University of La Plata, Argentina., Dardenne M; CNRS UMR8147, Paris Descartes University, Paris, France., Goya RG; Institute for Biochemical Research-Histology B-Pathology B, Faculty of Medicine, National University of La Plata, Argentina. Electronic address: goya@isis.unlp.edu.ar., Reggiani PC; Institute for Biochemical Research-Histology B-Pathology B, Faculty of Medicine, National University of La Plata, Argentina. Electronic address: paulareggiani@conicet.gov.ar.

Publikováno v: Molecular immunology [Mol Immunol] 2017 Jul; Vol. 87, pp. 180-187. Date of Electronic Publication: 2017 May 11.