Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Zao C. Xu"'
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2021)
Seizures are among the most common neurological sequelae of stroke, and diabetes notably increases the incidence of post-ischemic seizures. Recent studies have indicated that Sestrin3 (SESN3) is a regulator of a proconvulsant gene network in human ep
Externí odkaz:
https://doaj.org/article/97a12f30037940d5904ab20f678bf645
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24566 (2011)
Hippocampal injury-associated learning and memory deficits are frequent hallmarks of brain trauma and are the most enduring and devastating consequences following traumatic brain injury (TBI). Several reports, including our recent paper, showed that
Externí odkaz:
https://doaj.org/article/2bf8904c13984490937d5a9ec850be61
Publikováno v:
Springer Series in Translational Stroke Research ISBN: 9783030160807
Springer Protocols Handbooks ISBN: 9781603271844
Springer Protocols Handbooks ISBN: 9781603271844
Four-vessel occlusion model in rat induces transient forebrain ischemia that resembles cardiac arrest in clinical situations. In this model, two vertebral arteries are coagulated and two common carotid arteries are reversibly occluded. This model pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106ad8afb8ffb7e70a0fd2281327c498
https://doi.org/10.1007/978-3-030-16082-1_6
https://doi.org/10.1007/978-3-030-16082-1_6
Despite numerous recent studies and exciting discoveries in the field, only limited treatments are available today for the victims of acute brain and spinal cord injuries. Animal Models of Acute Neurological Injuries, Second Edition, provides a sta
Autor:
Zao C. Xu, Yannik Kalbas, Todd O. McKinley, Fan Wu, Zhigang Lei, Zhongshan Shi, Richard B. Rodgers, Fletcher A. White
Publikováno v:
The journal of trauma and acute care surgery. 85(6)
BACKGROUND Patients who sustain traumatic brain injury (TBI) and concomitant hemorrhagic shock (HS) are at high risk of high-magnitude inflammation which can lead to poor outcomes and death. Blood purification by hemoadsorption (HA) offers an alterna
Publikováno v:
Brain Research. 1590:75-84
Seizures are a common sequel of cerebral ischemia, and hyperglycemia markedly increases the onset of seizures following an ischemic insult. However, the underlying mechanism of seizures is unclear. The toll-like receptor 4 (TLR4) pathway is known to
Publikováno v:
Journal of Neuroscience Research. 92:1775-1784
Poststroke seizures are considered to be the major cause of epilepsy in the elderly. The mechanisms of poststroke seizures remain unclear. A history of diabetes mellitus has been identified as an independent predictor of acute poststroke seizures in
Publikováno v:
Journal of Neurotrauma. 29:235-245
Traumatic brain injury (TBI) is associated with cognitive deficits, memory impairment, and epilepsy. Previous studies have reported neuronal loss and neuronal hyperexcitability in the post-traumatic hippocampus. A-type K+ currents (I(A)) play a criti
Publikováno v:
Brain research. 1643
Seizures are among the most common neurological sequelae of stroke, and ischemic insult in diabetes notably increases the incidence of seizures. Recent studies indicated that autophagy influences the outcome of stroke and involved in epileptogenesis.
Autor:
Min Li, Zhiping P. Pang, Brandon K. Harvey, Barry London, Qiaojie Xiong, Sojin Shikano, Ping Deng, Zao C. Xu, Zhigang Lei, Yun Wang
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 31:1823-1835
Excitotoxicity is the major cause of many neurologic disorders including stroke. Potassium currents modulate neuronal excitability and therefore influence the pathological process. A-type potassium current ( IA) is one of the major voltage-dependent