Zobrazeno 1 - 10
of 643
pro vyhledávání: '"Zanivan"'
Autor:
Reid, SE, Kay, EJ, Neilson, LJ, Henze, AT, Serneels, J, McGhee, EJ, Dhayade, S, Nixon, C, Mackey, JB, Santi, A, Swaminathan, Karthic, Athineos, D, Papalazarou, V, Patella, F, Roman-Fernandez, A, ElMaghloob, Y, Hernandez-Fernaud, JR, Adams, RH, Ismail, S, Bryant, DM, Salmeron-Sanchez, M, Machesky, LM, Carlin, LM, Blyth, K, Mazzone, M, Zanivan, S
Yes
Tumor progression alters the composition and physical properties of the extracellular matrix. Particularly, increased matrix stiffness has profound effects on tumor growth and metastasis. While endothelial cells are key players in cancer pro
Tumor progression alters the composition and physical properties of the extracellular matrix. Particularly, increased matrix stiffness has profound effects on tumor growth and metastasis. While endothelial cells are key players in cancer pro
Externí odkaz:
http://hdl.handle.net/10454/17727
Autor:
Amy Dawson, Martha M. Zarou, Bodhayan Prasad, Joana Bittencourt-Silvestre, Désirée Zerbst, Ekaterini Himonas, Ya-Ching Hsieh, Isabel van Loon, Giovanny Rodriguez Blanco, Angela Ianniciello, Zsombor Kerekes, Vaidehi Krishnan, Puneet Agarwal, Hassan Almasoudi, Laura McCluskey, Lisa E. M. Hopcroft, Mary T. Scott, Pablo Baquero, Karen Dunn, David Vetrie, Mhairi Copland, Ravi Bhatia, Seth B. Coffelt, Ong Sin Tiong, Helen Wheadon, Sara Zanivan, Kristina Kirschner, G. Vignir Helgason
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Macrophages are fundamental cells of the innate immune system that support normal haematopoiesis and play roles in both anti-cancer immunity and tumour progression. Here we use a chimeric mouse model of chronic myeloid leukaemia (CML) and hu
Externí odkaz:
https://doaj.org/article/8f93c354e91945c2be6407a9da014cb7
Autor:
Lisa J. Neilson, Douglas Cartwright, Maija Risteli, Elina M. Jokinen, Lynn McGarry, Toni Sandvik, Konstantina Nikolatou, Kelly Hodge, Samuel Atkinson, Maria Vias, Emily J. Kay, James D. Brenton, Leo M. Carlin, David M. Bryant, Tuula Salo, Sara Zanivan
Publikováno v:
Matrix Biology Plus, Vol 19, Iss , Pp 100136- (2023)
High-grade serous (HGS) ovarian cancer is the most lethal gynaecological disease in the world and metastases is a major cause. The omentum is the preferential metastatic site in HGS ovarian cancer patients and in vitro models that recapitulate the or
Externí odkaz:
https://doaj.org/article/d4dce9ee5303495aaec66cd09d019f16
Autor:
Neilson, Lisa J., Cartwright, Douglas, Risteli, Maija, Jokinen, Elina M., McGarry, Lynn, Sandvik, Toni, Nikolatou, Konstantina, Hodge, Kelly, Atkinson, Samuel, Vias, Maria, Kay, Emily J., Brenton, James D., Carlin, Leo M., Bryant, David M., Salo, Tuula, Zanivan, Sara
Publikováno v:
In Matrix Biology Plus December 2023 19-20
Publikováno v:
In Current Opinion in Biotechnology December 2023 84
Autor:
Emily J. Kay, Sara Zanivan
Publikováno v:
Molecular Oncology, Vol 17, Iss 4, Pp 541-544 (2023)
Bicarbonate transport is a pre‐existing mechanism of pH regulation in pancreatic ductal cells. In a recent study, Cappellesso et al. demonstrated that pancreatic ductal adenocarcinoma metabolic rewiring creates an acidic environment, enhanced by bi
Externí odkaz:
https://doaj.org/article/209cd0c38096484d835c7aa0bc78cb90
Autor:
Noemi Gioelli, Lisa J. Neilson, Na Wei, Giulia Villari, Wenqian Chen, Bernhard Kuhle, Manuel Ehling, Federica Maione, Sander Willox, Serena Brundu, Daniele Avanzato, Grigorios Koulouras, Massimiliano Mazzone, Enrico Giraudo, Xiang-Lei Yang, Donatella Valdembri, Sara Zanivan, Guido Serini
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Functional vascular tree formation is a key step in many contexts, such as cancer, and Neuropilin1 (NRP1) has been associated with adhesion receptor endocytic turnover. Here, authors show NRP1 and its mini-WARS ligand play a role in reducing endothel
Externí odkaz:
https://doaj.org/article/2f35d1709b354aba9e4278bad5764f45
Autor:
Närvä, Elisa, Taskinen, Maria E., Lilla, Sergio, Isomursu, Aleksi, Pietilä, Mika, Weltner, Jere, Isola, Jorma, Sihto, Harri, Joensuu, Heikki, Zanivan, Sara, Norman, Jim, Ivaska, Johanna
Publikováno v:
In iScience 17 June 2022 25(6)
Autor:
Sergi Marco, Matthew Neilson, Madeleine Moore, Arantxa Perez-Garcia, Holly Hall, Louise Mitchell, Sergio Lilla, Giovani R. Blanco, Ann Hedley, Sara Zanivan, Jim C. Norman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Effective delivery of signals from the cell surface to the nucleus is a key to activate gene transcription. Here, the authors show how endosomes containing EphA2 are transported and captured at the nuclear surface, triggering depletion of G-actin fro
Externí odkaz:
https://doaj.org/article/5026a0dde67b478d8be77b8ddb4c8629
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