Interleukin-5 as a pleiotropic cytokine orchestrating airway type 2 inflammation: Effects on and beyond eosinophils.

Autor: Buchheit KM; Division of Allergy and Clinical Immunology, AERD Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA., Shaw D; Department of Respiratory Medicine and Thoracic Surgery, Institute for Lung Health, Glenfield Hospital, Leicester, UK., Chupp G; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA., Lehtimaki L; Faculty of Medicine and Health Technology, Allergy Centre, Tampere University Hospital, Tampere University, Tampere, Finland., Heffler E; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Personalized Medicine, Asthma and Allergy Clinic, IRCCS Humanitas Research Hospital, Milan, Italy., Finney-Hayward T; Global Medical Affairs, Respiratory Specialty Care, GSK, London, UK., Zangrilli J; Clinical Science, GSK, Collegeville, Pennsylvania, USA., Kwiatek J; US Medical Affairs, GSK, Collegeville, Pennsylvania, USA., Siddiqui S; National Heart and Lung Institute, NIHR Imperial Biomedical Research Centre, Imperial College London, London, UK., Roufosse F; Department of Internal Medicine, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium., Thamboo A; Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada., West N; School of Pharmacy and Medical Sciences, Griffith University, Southport, Queensland, Australia., Vichiendilokkul A; Clinical Science, GSK, Collegeville, Pennsylvania, USA., Hellings PW; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium.; Upper Airways Disease Research Unit, University of Ghent, Ghent, Belgium., Peters A; Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Howarth PH; Global Medical Affairs, Respiratory Specialty Care, GSK, London, UK.

Publikováno v: Allergy [Allergy] 2024 Oct; Vol. 79 (10), pp. 2662-2679.

International Severe Asthma Registry Mission Statement

Autor: Canonica, GW, Alacqua, M, Altraja, A, Backer, V, Bel, E, Bjermer, L, Bjornsdottir, U, Bourdin, A, Brusselle, GG, Christoff, GC, Cosio, BG, Costello, RW, FitzGerald, JM, Gibson, PG, Heaney, LG, Heffler, E, Hew, M, Iwanaga, T, Jones, RC, Siyue, MK, Rhee, CK, Lehmann, S, Lehtimaki, LA, Ludviksdottir, D, Maitland-van der Zee, AH, Menzies-Gow, AN, Papadopoulos, NG, Plaza, V, de Llano, LP, Peters, M, Porsbjerg, CM, Sadatsafavi, M, Cho, YS, Tohda, Y, Tran, TN, Wang, E, Zangrilli, J, Bulathsinhala, L, Carter, VA, Chaudhry, I, Eleangovan, N, Hosseini, N, Le, TL, Murray, RB, Price, CA, Price, DB, ISAR Study Grp

Publikováno v: CHEST
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Regional and/or national severe asthma registries provide valuable country-specific information. However, they are often limited in scope within the broader definitions of severe asthma, have insufficient statistical power to answer many research que

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0fe1f55e9ad96a605bdba5eb30b0a866
https://hdl.handle.net/20.500.13003/17248

Safety and Duration of Low-Dose Adjuvant Dexamethasone in Regional Anesthesia for Upper Extremity Surgery: A Prospective, Randomized, Controlled Blinded Study.

Autor: Gouda N; Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA., Zangrilli J; Rowan School of Osteopathic Medicine, Stratford, NJ, USA., Voskerijian A; Jefferson Surgery Center at the Navy Yard, Philadelphia, PA, USA.; United Anesthesia Services, P.C., Bryn Mawr, PA, USA., Wang ML; Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA., Beredjiklian PK; Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA., Rivlin M; Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA.

Publikováno v: Hand (New York, N.Y.) [Hand (N Y)] 2022 Nov; Vol. 17 (6), pp. 1236-1241. Date of Electronic Publication: 2021 Apr 21.

Effect of IL-5, glucocorticoid, and Fas ligation on Bcl-2 homologue expression and caspase activation in circulating human eosinophils.

Autor: Zangrilli, J.¹, Robertson, N.², Shetty, A.¹, Wu, J.¹, Hastie, A.¹, Fish, J. E.¹, Litwack, G.², Peters, S. P.¹

Publikováno v: Clinical & Experimental Immunology. Apr2000, Vol. 120 Issue 1, p12-21. 10p.

Eosinophilic and Noneosinophilic Asthma: An Expert Consensus Framework to Characterize Phenotypes in a Global Real-Life Severe Asthma Cohort.

Autor: Heaney LG; UK Severe Asthma Network and National Registry, Queen's University Belfast, Belfast, United Kingdom., Perez de Llano L; Pneumology Service, Lucus Augusti University Hospital, EOXI Lugo, Monforte, Cervo, Lugo, Biodiscovery Research Group, Health Research Institute of Santiago de Compostela, Spain., Al-Ahmad M; Al-Rashed Allergy Center, Ministry of Health, Microbiology Department, Faculty of Medicine, Kuwait University, Kuwait., Backer V; Centre for Physical Activity Research, Rigshospitalet, Copenhagen University, Copenhagen, Denmark; Department of ENT, Rigshospitalet, Copenhagen University, Copenhagen, Denmark., Busby J; UK Severe Asthma Network and National Registry, Queen's University Belfast, Belfast, United Kingdom., Canonica GW; Personalized Medicine, Asthma and Allergy, Humanitas Clinical and Research Center IRCCS, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Christoff GC; Faculty of Public Health, Medical University - Sofia, Sofia, Bulgaria., Cosio BG; Son Espases University Hospital-IdISBa-Ciberes, Mallorca, Spain., FitzGerald JM; Centre for Lung Health, Vancouver, BC, Canada., Heffler E; Personalized Medicine, Asthma and Allergy, Humanitas Clinical and Research Center IRCCS, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Iwanaga T; Center for General Medical Education and Clinical Training, Kindai University Hospital, Osakasayama, Japan., Jackson DJ; UK Severe Asthma Network and National Registry, Guy's and St Thomas' NHS Trust, London, United Kingdom; School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Menzies-Gow AN; UK Severe Asthma Network and National Registry, Royal Brompton & Harefield Hospitals, London, UK., Papadopoulos NG; Division of Infection, Immunity & Respiratory Medicine, University of Manchester, Manchester, United Kingdom; Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece., Papaioannou AI; 2nd Respiratory Medicine Department, National and Kapodistrian University of Athens Medical School, Attikon University Hospital, Athens, Greece., Pfeffer PE; Department of Respiratory Medicine, Barts Health NHS Trust, The London School of Medicine and Dentistry, Queen Mary University of London, London, UK; UK Severe Asthma Network, Barts Health NHS Trust, London, United Kingdom., Popov TA; University Hospital 'Sv. Ivan Rilski', Sofia, Bulgaria., Porsbjerg CM; Respiratory Research Unit, Bispebjerg University Hospital, Copenhagen, Denmark., Rhee CK; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea., Sadatsafavi M; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada., Tohda Y; Center for General Medical Education and Clinical Training, Kindai University Hospital, Osakasayama, Japan., Wang E; Division of Allergy & Clinical Immunology, Department of Medicine, National Jewish Health, Denver, CO; Division of Allergy & Clinical Immunology, Department of Internal Medicine, University of Colorado School of Medicine, Aurora, CO., Wechsler ME; NJH Cohen Family Asthma Institute, Department of Medicine, National Jewish Health, Denver, CO., Alacqua M; AstraZeneca, Cambridge, United Kingdom., Altraja A; Department of Pulmonary, University of Tartu and Lung Clinic, Tartu University Hospital, Tartu, Estonia., Bjermer L; Respiratory Medicine and Allergology, Department of Clinical Sciences, Skåne University Hospital, Lund University, Lund, Sweden., Björnsdóttir US; Department of Respiratory Medicine and Allergy, Landspitali The University Hospital of Iceland, Reykjavik, Iceland., Bourdin A; PhyMedExp, Univ Montpellier, CNRS, INSERM, CHU Montpellier, Montpellier, France., Brusselle GG; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium; Department of Epidemiology and Respiratory Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands., Buhl R; Pulmonary Department, Mainz University Hospital, Mainz, Germany., Costello RW; Clinical Research Centre, Smurfit Building Beaumont Hospital and Department of Respiratory Medicine, RCSI, Dublin, Ireland., Hew M; Allergy, Asthma & Clinical Immunology Service, Alfred Health, Melbourne, Australia; Public Health and Preventive Medicine, Monash University, Melbourne, Australia., Koh MS; Respiratory & Critical Care Medicine, Singapore General Hospital, Singapore, Republic of Singapore; SingHealth Duke-NUS Lung Centre, Singapore, Republic of Singapore., Lehmann S; Section of Thoracic Medicine, Department of Clinical Science, University of Bergen, Bergen, Norway., Lehtimäki L; Allergy Centre, Tampere University Hospital, and Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Peters M; Department of Thoracic Medicine, Concord Hospital, Sydney, Australia., Taillé C; Department of Respiratory Diseases, Bichat Hospital, AP-HP Nord-Université de Paris; Paris, France., Taube C; Department of Pulmonary Medicine, University Medical Center Essen-Ruhrlandklinik, Essen, Germany., Tran TN; AstraZeneca, Gaithersburg, MD., Zangrilli J; AstraZeneca, Gaithersburg, MD., Bulathsinhala L; Optimum Patient Care, Cambridge, United Kingdom., Carter VA; Optimum Patient Care, Cambridge, United Kingdom., Chaudhry I; Optimum Patient Care, Cambridge, United Kingdom., Eleangovan N; Optimum Patient Care, Cambridge, United Kingdom., Hosseini N; Optimum Patient Care, Cambridge, United Kingdom., Kerkhof M; Optimum Patient Care, Cambridge, United Kingdom., Murray RB; Optimum Patient Care, Cambridge, United Kingdom., Price CA; Optimum Patient Care, Cambridge, United Kingdom., Price DB; Optimum Patient Care, Cambridge, United Kingdom; Centre of Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom; Observational and Pragmatic Research Institute, Singapore, Republic of Singapore. Electronic address: dprice@opri.sg.

Publikováno v: Chest [Chest] 2021 Sep; Vol. 160 (3), pp. 814-830. Date of Electronic Publication: 2021 Apr 19.