Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Zanghellini, P."'
Autor:
Guido Schlögel, Rüdiger Lück, Stefan Kittler, Oliver Spadiut, Julian Kopp, Jürgen Zanghellini, Mathias Gotsmy
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3651-3661 (2024)
Biotechnological production of recombinant molecules relies heavily on fed-batch processes. However, as the cells' growth, substrate uptake, and production kinetics are often unclear, the fed-batches are frequently operated under sub-optimal conditio
Externí odkaz:
https://doaj.org/article/6983b0e5badc40938f42463311c9a8c0
Autor:
Maria Marta Neves de Oliveira Freire, Jerônimo Mendes Ribeiro, Igor Emanuel Vasconcelos e Martins Gomes, Sarah Cristina Zanghellini Rückl, Maria Angélica Antunes Nunes, Christiane Carvalho Ribeiro, Antônio Geraldo da Silva, Joel Rennó Junior
Publikováno v:
Debates em Psiquiatria, Vol 14 (2024)
Introdução: A perda de um filho é uma experiência devastadora, principalmente no período perinatal, com especificidades que a tornam única. Há um importante impacto financeiro no sistema de saúde, com aumento do risco de surgimento de luto co
Externí odkaz:
https://doaj.org/article/296f9427547c48eda901a569473f1eda
MeXposeA Modular Imaging Pipeline for the Quantitative Assessment of Cellular Metal Bioaccumulation
Autor:
Gabriel Braun, Martin Schaier, Paulina Werner, Sarah Theiner, Jürgen Zanghellini, Lukas Wisgrill, Nanna Fyhrquist, Gunda Koellensperger
Publikováno v:
JACS Au, Vol 4, Iss 6, Pp 2197-2210 (2024)
Externí odkaz:
https://doaj.org/article/7e3d0cf0d6e54cbb93058142b0a6e3bc
Autor:
Viktor Laurin Sedlmayr, Diana Széliová, Veerke De Kock, Yannick Gansemans, Filip Van Nieuwerburgh, Eveline Peeters, Julian Quehenberger, Jürgen Zanghellini, Oliver Spadiut
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Overflow metabolism is a well-known phenomenon that describes the seemingly wasteful and incomplete substrate oxidation by aerobic cells, such as yeasts, bacteria, and mammalian cells, even when conditions allow for total combustion via respiration.
Externí odkaz:
https://doaj.org/article/8bfd793e02df4276bf25be5773f88434
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Ribosomes are key to cellular self-fabrication and limit growth rate. While most enzymes are proteins, ribosomes consist of 1/3 protein and 2/3 ribonucleic acid (RNA) (in E. coli). Here, we develop a mechanistic model of a self-fabricating c
Externí odkaz:
https://doaj.org/article/1bd374533e0e4d2e977dac43cd43b214
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 6, p e1012236 (2024)
Genome-scale metabolic models (GSMMs) offer a holistic view of biochemical reaction networks, enabling in-depth analyses of metabolism across species and tissues in multiple conditions. However, comparing GSMMs Against each other poses challenges as
Externí odkaz:
https://doaj.org/article/76f5939ea13c489e9d747553242b679f
Autor:
Mathias Gotsmy, Florian Strobl, Florian Weiß, Petra Gruber, Barbara Kraus, Juergen Mairhofer, Jürgen Zanghellini
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-16 (2023)
Abstract Plasmid DNA (pDNA) is a key biotechnological product whose importance became apparent in the last years due to its role as a raw material in the messenger ribonucleic acid (mRNA) vaccine manufacturing process. In pharmaceutical production pr
Externí odkaz:
https://doaj.org/article/70273fc1ce8e443c95047315ca625696
Metabolic modeling strives to develop modeling approaches that are robust and highly predictive. To achieve this, various modeling designs, including hybrid models, and parameter estimation methods that define the type and number of parameters used i
Externí odkaz:
http://arxiv.org/abs/2104.11624
Autor:
Ana Paula Maia Dal Moro, Gabriella Soecki, Fernanda Schier de Fraga, Ricardo Rasmussen Petterle, Sarah Zanghellini Rückl
Publikováno v:
BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background The fear of childbirth (FOC) harms maternal and fetal health, however it has been little studied in Brazil. This research aimed to determine the prevalence of FOC in a maternity hospital in southern Brazil and identify its associa
Externí odkaz:
https://doaj.org/article/3c3ae628cc8242f7b4685c76ee3aa917
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