Unnatural Endotype B PPAPs as Novel Compounds with Activity against Mycobacterium tuberculosis .

Autor: Peslalz P; Chair of Organic Chemistry, Faculty of Chemistry and Food Chemistry, Technical University Dresden, Bergstr. 66, Dresden01069 ,Germany., Grieshober M; Institute for Medical Microbiology and Hygiene, University Hospital Ulm, Albert-Einstein-Allee 11, Ulm D-89081, Germany., Kraus F; Institut für Organische Chemie, Universität Stuttgart,Pfaffenwaldring 55, Stuttgart 70569, Germany., Bleisch A; Chair of Organic Chemistry, Faculty of Chemistry and Food Chemistry, Technical University Dresden, Bergstr. 66, Dresden01069 ,Germany., Izzo F; Institut für Organische Chemie, Universität Stuttgart,Pfaffenwaldring 55, Stuttgart 70569, Germany., Lichtenstein D; Department of Food Safety, German Federal Institute for Risk Assessment, Max-Dohrn-Str. 8-10, Berlin 10589, Germany., Hammer H; SIGNATOPE GmbH, Markwiesenstr. 55, Reutlingen 72770, Germany., Vorbach A; Interfaculty Institute of Microbiology and Infection Medicine, Tübingen 72076, Germany., Momoi K; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology Auerbachstr. 112, University of Tübingen, 70376 Stuttgart, Tübingen 72076, Germany., Zanger UM; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology Auerbachstr. 112, University of Tübingen, 70376 Stuttgart, Tübingen 72076, Germany., Brötz-Oesterhelt H; Interfaculty Institute of Microbiology and Infection Medicine, Tübingen 72076, Germany.; German Center for Infection Research, Partner Site Tübingen, Tübingen 72076, Germany., Braeuning A; Department of Food Safety, German Federal Institute for Risk Assessment, Max-Dohrn-Str. 8-10, Berlin 10589, Germany., Plietker B; Chair of Organic Chemistry, Faculty of Chemistry and Food Chemistry, Technical University Dresden, Bergstr. 66, Dresden01069 ,Germany.; Institut für Organische Chemie, Universität Stuttgart,Pfaffenwaldring 55, Stuttgart 70569, Germany., Stenger S; Institute for Medical Microbiology and Hygiene, University Hospital Ulm, Albert-Einstein-Allee 11, Ulm D-89081, Germany.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2023 Nov 23; Vol. 66 (22), pp. 15073-15083. Date of Electronic Publication: 2023 Oct 12.

Drug metabolism in animal models and humans: Translational aspects and chances for individual therapy.

Autor: Indorf, Patrick¹ (AUTHOR) patrick.indorf@charite.de, Patzak, Andreas¹ (AUTHOR), Lichtenberger, Falk‐Bach¹ (AUTHOR)

Publikováno v: Acta Physiologica. Dec2021, Vol. 233 Issue 4, p1-5. 5p. 1 Diagram, 1 Graph.

Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis.

Autor: Heintze T; Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; Eberhard Karls University, Tübingen, Germany., Wilhelm D; Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany., Schmidlin T; Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; Eberhard Karls University, Tübingen, Germany.; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Hofmann U; Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; Eberhard Karls University, Tübingen, Germany., Zanger UM; Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; Eberhard Karls University, Tübingen, Germany., Schwab M; Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; Departments of Clinical Pharmacology and Biochemistry and Pharmacy, University of Tuebingen, Tübingen, Germany.; Cluster of Excellence IFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany., Klein K; Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; Eberhard Karls University, Tübingen, Germany.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2021 Nov 15; Vol. 12, pp. 769703. Date of Electronic Publication: 2021 Nov 15 (Print Publication: 2021).

Pharmacogenotyping disproves genetic cause of drug-related problems in family history: a case report.

Autor: Bollinger, Anna¹ a.bollinger@unibas.ch, Hersberger, Kurt E.¹, Meyer zu Schwabedissen, Henriette E.¹, Allemann, Samuel S.¹, Stäuble, Céline K.^1,2

Publikováno v: BMC Anesthesiology. 11/15/2024, Vol. 24 Issue 1, p1-9. 9p.

Correction to: Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression.

Autor: Asperger H; Department of Obstetrics and Gynecology, University Hospital and Medical Faculty of the Heinrich-Heine University Duesseldorf, Life Science Center, Merowingerplatz 1A, 40225, Düsseldorf, Germany., Stamm N; Department of Obstetrics and Gynecology, University Hospital and Medical Faculty of the Heinrich-Heine University Duesseldorf, Life Science Center, Merowingerplatz 1A, 40225, Düsseldorf, Germany., Gierke B; NMI TT Pharmaservices, Protein Profiling, Reutlingen, Germany., Pawlak M; NMI TT Pharmaservices, Protein Profiling, Reutlingen, Germany., Hofmann U; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology and University of Tübingen, Stuttgart, Germany., Zanger UM; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology and University of Tübingen, Stuttgart, Germany., Marton A; Institute of Biochemistry, Biological Research Centre, Szeged, Hungary., Katona RL; Institute of Genetics, Biological Research Centre, Szeged, Hungary., Buhala A; Institute of Biochemistry, Biological Research Centre, Szeged, Hungary., Vizler C; Institute of Biochemistry, Biological Research Centre, Szeged, Hungary., Cieslik JP; Department of Obstetrics and Gynecology, University Hospital and Medical Faculty of the Heinrich-Heine University Duesseldorf, Life Science Center, Merowingerplatz 1A, 40225, Düsseldorf, Germany., Kovacevic Z; School of Medical Sciences, Faculty of Medicine and Health, Medical Foundation Building, University of Sydney, Sydney, New South Wales, 2006, Australia., Richardson DR; Centre for Cancer Cell Biology and Drug Discovery, Griffith Institute for Drug Discovery, Griffith University, Brisbane, Queensland, 4111, Australia., Ruckhäberle E; Department of Obstetrics and Gynecology, University Hospital and Medical Faculty of the Heinrich-Heine University Duesseldorf, Life Science Center, Merowingerplatz 1A, 40225, Düsseldorf, Germany., Niederacher D; Department of Obstetrics and Gynecology, University Hospital and Medical Faculty of the Heinrich-Heine University Duesseldorf, Life Science Center, Merowingerplatz 1A, 40225, Düsseldorf, Germany., Fehm T; Department of Obstetrics and Gynecology, University Hospital and Medical Faculty of the Heinrich-Heine University Duesseldorf, Life Science Center, Merowingerplatz 1A, 40225, Düsseldorf, Germany., Neubauer H; Department of Obstetrics and Gynecology, University Hospital and Medical Faculty of the Heinrich-Heine University Duesseldorf, Life Science Center, Merowingerplatz 1A, 40225, Düsseldorf, Germany. Hans.Neubauer@med.uni-duesseldorf.de., Ludescher M; Department of Obstetrics and Gynecology, University Hospital and Medical Faculty of the Heinrich-Heine University Duesseldorf, Life Science Center, Merowingerplatz 1A, 40225, Düsseldorf, Germany.

Publikováno v: Breast cancer research : BCR [Breast Cancer Res] 2021 Jan 28; Vol. 23 (1), pp. 13. Date of Electronic Publication: 2021 Jan 28.