Engineered human pluripotent stem cell lines for following differentiation into pancreatic islets and addressing their maturation

Autor: Zanfrini, Elisa

Externí odkaz: https://tud.qucosa.de/id/qucosa%3A89080
https://tud.qucosa.de/api/qucosa%3A89080/attachment/ATT-0/

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Generation of fertile cloned bull knock out for galactose-alpha 1,3-galactose and N-glycolylneuraminic acid antigens

Autor: Perota, Andrea, Lagutina, Irina, Duchi, Roberto, Zanfrini, Elisa, Lazzari, Giovanna, Judor, Jean Paul, Conchon, Sophie, Bach, Jean-Marie, Bottio, Tomaso, Gerosa, Gino, Costa, Cristina, Galiñanes, Manuel, Roussel, Jean Christian, Padler-Karavani, Vered, Cozzi, Emanuele, Soulillou, Jean Paul, Galli, Cesare

Publikováno v: Xenotransplantation
15th Congress of the International-Xenotransplantation-Association (IXA)
15th Congress of the International-Xenotransplantation-Association (IXA), Oct 2019, Munich, Germany. pp.2

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e95754554320ce20bf12336535c98bae
https://hal.inrae.fr/hal-02735245

Introduction of the TLA sequencing analyses for a better identification of the transgene integrations, to select porcine founder animals for breeding

Autor: Perota, Andrea, Mourad, Nizar, Lagutina, Irina, Duchi, Roberto, Zanfrini, Elisa, Lazzari, Giovanna, Gianello, Pierre, Galli, Cesare, 15th Congress of the International Xenotransplantation Association (IXA 2019)

Publikováno v: Xenotransplantation, Vol. 26, no. 5, p. e12553 (48)

Xenotransplantation of modified pig islets could be a possible medical treatment for T1/T2 diabetic patients. Tailored genetic engineering of a genomic safe harbor locus assisted by programmable nucleases (ZFNs, TALENs and CRISPR/Cas9) is making easi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1493::87e1fce372c937e3ae78807b3425db85
https://hdl.handle.net/2078.1/220487

Unexpected impairment of I Na underpins reentrant arrhythmias in a knock-in swine model of Timothy syndrome.

Autor: Porta-Sánchez A; Novel Arrhythmogenic Mechanism Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain., Mazzanti A; Novel Arrhythmogenic Mechanism Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy.; Department of Molecular Medicine, University of Pavia, Pavia, Italy., Tarifa C; Novel Arrhythmogenic Mechanism Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain., Kukavica D; Novel Arrhythmogenic Mechanism Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy.; Department of Molecular Medicine, University of Pavia, Pavia, Italy., Trancuccio A; Novel Arrhythmogenic Mechanism Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy.; Department of Molecular Medicine, University of Pavia, Pavia, Italy., Mohsin M; Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy., Zanfrini E; AVANTEA, Cremona, Italy., Perota A; AVANTEA, Cremona, Italy., Duchi R; AVANTEA, Cremona, Italy., Hernandez-Lopez K; Novel Arrhythmogenic Mechanism Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain., Jáuregui-Abularach ME; Novel Arrhythmogenic Mechanism Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain., Pergola V; Novel Arrhythmogenic Mechanism Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy., Fernandez E; Novel Arrhythmogenic Mechanism Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain., Bongianino R; Novel Arrhythmogenic Mechanism Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy., Tavazzani E; Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy., Gambelli P; Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy., Memmi M; Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy., Scacchi S; Department of Mathematics, University of Milan, Milano, Italy., Pavarino LF; Department of Mathematics, University of Pavia, Pavia, Italy., Franzone PC; Novel Arrhythmogenic Mechanism Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy.; Department of Molecular Medicine, University of Pavia, Pavia, Italy.; AVANTEA, Cremona, Italy.; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.; Department of Mathematics, University of Milan, Milano, Italy.; Department of Mathematics, University of Pavia, Pavia, Italy.; Department of Pharmacology, University of Bari, Bari, Italy.; Cardiovascular Institute, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Madrid, Spain., Lentini G; Department of Pharmacology, University of Bari, Bari, Italy., Filgueiras-Rama D; Novel Arrhythmogenic Mechanism Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Cardiovascular Institute, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Madrid, Spain., Galli C; AVANTEA, Cremona, Italy., Santiago DJ; Novel Arrhythmogenic Mechanism Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain., Priori SG; Novel Arrhythmogenic Mechanism Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.; Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy.; Department of Molecular Medicine, University of Pavia, Pavia, Italy.

Publikováno v: Nature cardiovascular research [Nat Cardiovasc Res] 2023; Vol. 2 (12), pp. 1291-1309. Date of Electronic Publication: 2023 Dec 11.