Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Zaneta Sibinska"'
Autor:
Mario Boehm, Norbert Weissmann, Ralph T. Schermuly, Tatyana Novoyatleva, Guido Posern, Xia Tian, Zaneta Sibinska, Himal Luitel, Chris Happé, Amna Sajjad, Hossein Ardeschir Ghofrani, Harm Jan Bogaard, Steven Evans, Baktybek Kojonazarov, Werner Seeger, Friedrich Grimminger, Philipp Kriechling
Publikováno v:
Kojonazarov, B, Novoyatleva, T, Boehm, M, Happe, C, Sibinska, Z, Tian, X, Sajjad, A, Luitel, H, Kriechling, P, Posern, G, Evans, S M, Grimminger, F, Ghofrani, H A, Weissmann, N, Bogaard, H J, Seeger, W & Schermuly, R T 2017, ' P38 mapk inhibition improves heart function in pressure-loaded right ventricular hypertrophy ', American Journal of Respiratory Cell and Molecular Biology, vol. 57, no. 5, pp. 603-614 . https://doi.org/10.1165/rcmb.2016-0374OC
American Journal of Respiratory Cell and Molecular Biology, 57(5), 603-614. American Thoracic Society
American Journal of Respiratory Cell and Molecular Biology, 57(5), 603-614. American Thoracic Society
Although p38 mitogen-activated protein kinase (MAPK) is known to have a role in ischemic heart disease and many other diseases, its contribution to the pathobiology of right ventricular (RV) hypertrophy and failure is unclear. Therefore, we sought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605794b8b375785b16594454ee7eaec8
https://doi.org/10.1165/rcmb.2016-0374oc
https://doi.org/10.1165/rcmb.2016-0374oc
Autor:
David Gray, Katherine Miles, Mohini Gray, Zaneta Sibinska, Jonathan Heaney, John Savill, Donald Salter
Publikováno v:
Miles, K, Heaney, J, Sibinska, Z, Salter, D, Savill, J, Gray, D & Gray, M 2012, ' A tolerogenic role for Toll-like receptor 9 is revealed by B-cell interaction with DNA complexes expressed on apoptotic cells ', Proceedings of the National Academy of Sciences, vol. 109, no. 3, pp. 887-892 . https://doi.org/10.1073/pnas.1109173109
Intracellular protein complexes containing nucleic acids are common targets of autoantibodies in many autoimmune diseases. Central tolerance to these antigens is incomplete, yet nucleosomal DNA is expressed on the surface of cells dying by apoptosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0698b69d9c71c5ef66f6717b915ffdf9
https://doi.org/10.1073/pnas.1109173109
https://doi.org/10.1073/pnas.1109173109
Autor:
Paula E. Beaumont, Donald J. Davidson, Zaneta Sibinska, Mohini Gray, Wuyuan Lu, David Clarke, Tom A. Barr, Dominic J. Campopiano, Katherine Miles
Publikováno v:
Miles, K, Clarke, D J, Lu, W, Sibinska, Z, Beaumont, P E, Davidson, D J, Barr, T A, Campopiano, D J & Gray, M 2009, ' Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins ', Journal of Immunology, vol. 183, no. 3, pp. 2122-2132 . https://doi.org/10.4049/jimmunol.0804187
Neutrophils are recruited to sites of injury but their timely removal is thought to be vital to prevent exacerbating inflammation. In addition, the recognition of apoptotic cells by cells of the innate immune system provides potent anti-inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc69463565b7c87d2cdcda6fd0c5f9c
https://doi.org/10.4049/jimmunol.0804187
https://doi.org/10.4049/jimmunol.0804187
Autor:
Zaneta, Sibinska, Xia, Tian, Martina, Korfei, Baktybek, Kojonazarov, Janina Susanne, Kolb, Walter, Klepetko, Djuro, Kosanovic, Malgorzata, Wygrecka, Hossein Ardeschir, Ghofrani, Norbert, Weissmann, Friedrich, Grimminger, Werner, Seeger, Andreas, Guenther, Ralph T, Schermuly
Publikováno v:
The European respiratory journal. 49(2)
Interstitial lung fibroblast activation coupled with extracellular matrix production is a pathological signature of idiopathic pulmonary fibrosis (IPF), and is governed by transforming growth factor (TGF)-β/Smad signalling. We sought to define the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44e4d9ec4b2d0792d8ca43ddc3099878
https://pubmed.ncbi.nlm.nih.gov/28232414
https://pubmed.ncbi.nlm.nih.gov/28232414
Autor:
Ralph T. Schermuly, Janina Susanne Kolb, Friedrich Grimminger, Walter Klepetko, Zaneta Sibinska, Martina Korfei, Andreas Guenther, Djuro Kosanovic, Norbert Weissmann, Hossein Ardeschir Ghofrani, Xia Tian, Malgorzata Wygrecka, Baktybek Kojonazarov, Werner Seeger
Publikováno v:
European Respiratory Journal. 49:1501941
Interstitial lung fibroblast activation coupled with extracellular matrix production is a pathological signature of idiopathic pulmonary fibrosis (IPF), and is governed by transforming growth factor (TGF)-β/Smad signalling. We sought to define the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5baceff204c423b37b3fb8a8b44e53b0
https://doi.org/10.1183/13993003.01941-2015
https://doi.org/10.1183/13993003.01941-2015
Autor:
Tomasz Rzymski, Mariusz Milik, Renata Windak, Katarzyna Prymula, Marek Cholody, Adrian Zarebski, Agnieszka Klosowska-Wardega, Zaneta Sibinska, Ewa Trebacz, Krzysztof Brzózka, Nicolas Beuzen, Agnieszka Szamborska-Gbur
Publikováno v:
Cancer Research. 72:3845-3845
The mitotic machinery is a validated target for potential drug therapies in cancer. However, anti-mitotic agents are not without complications from various side effects, notably neurological and hematological toxicities. There is much interest in ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00e367417e4ee25d9df884b0cdbd20a9
https://doi.org/10.1158/1538-7445.am2012-3845
https://doi.org/10.1158/1538-7445.am2012-3845
Autor:
Malgorzata Zurawska, Tomasz Rzymski, Piotr Kowalczyk, Marek Cholody, Zaneta Sibinska, Krzysztof Brzózka, Katarzyna Prymula, Nicolas Beuzen, Agnieszka Klosowska-Wardega, Wojciech Czardybon, Monika Guratowska, Renata Windak, Mariusz Milik, Karolina Krawczynska, Aleksandra Sabiniarz, Ewa Trebacz, Agnieszka Szamborska-Gbur
Publikováno v:
Molecular Cancer Therapeutics. 10:A243-A243
The family of Pim kinases emerged as a novel and interesting target with significant potential for therapeutic intervention in cancer. All three members of the family Pim-1, Pim-2 and Pim-3 were shown to be prevent apoptosis, promote protein translat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::749417ba801ee652947aed48d153d228
https://doi.org/10.1158/1535-7163.targ-11-a243
https://doi.org/10.1158/1535-7163.targ-11-a243
Autor:
Krzysztof Brzózka, Agnieszka Klosowska-Wardega, Tomasz Rzymski, Ewa Trebacz, Agnieszka Szamborska-Gbur, Zaneta Sibinska, Katarzyna Prymula, Mariusz Milik, Adrian Zarebski, Wojciech Czardybon, Karolina Krawczynska, Marek Cholody, Renata Windak, Nicolas Beuzen
Publikováno v:
Molecular Cancer Therapeutics. 10:B242-B242
The mitotic machinery is a validated target for potential drug therapies in cancer. Anti-mitotic drugs like vinca alkaloids and taxanes interfering with microtubules are important classes of chemotherapeutical agents. However, these agents are not wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::008a68259871326283f9ac37ef885a23
https://doi.org/10.1158/1535-7163.targ-11-b242
https://doi.org/10.1158/1535-7163.targ-11-b242
Autor:
Beate Schneider, Werner Seeger, Andreas Günther, Roxana Wasnick, Stefanie Hezel, Zaneta Sibinska, Jilada Wilhelm, Ralph T. Schermuly, Salma Dilai, Martina Korfei, Ingrid Henneke, Walter Klepetko, Elie El Agha, Saverio Bellusci, BreAnne MacKenzie, Xia Tian
Publikováno v:
Respiratory Research
Background Recent clinical studies show that tyrosine kinase inhibitors slow the rate of lung function decline and decrease the number of acute exacerbations in patients with Idiopathic Pulmonary Fibrosis (IPF). However, in the murine bleomycin model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d296e4743470cad2f9124be28aaecd7